APR03850G

antibody from Leading Biology

Targeting: MMP13 CLG3

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APR03850G

Provider

Leading Biology

Product name

MMP13 Antibody (Center)

Antibody type

Polyclonal

Description

Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The protein encoded by this genecleaves type II collagen more efficiently than types I and III. Itmay be involved in articular cartilage turnover and cartilagepathophysiology associated with osteoarthritis. The gene is part ofa cluster of MMP genes which localize to chromosome 11q22.3.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.