Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations [0]
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- Product number
- MAB511 - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-Human MMP-13 Monoclonal Antibody (Clone 87512)
- Antibody type
- Monoclonal
- Antigen
- Chinese hamster ovary cell line CHO-derived recombinant human MMP-13, Leu20-Cys471
- Description
- Protein A or G purified from hybridoma culture supernatant
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
P45452
- Isotype
- IgG
- Vial size
- 500 µg
Submitted references Diverse matrix metalloproteinase functions regulate cancer amoeboid migration.
Toll-like receptor 9 ligands enhance mesenchymal stem cell invasion and expression of matrix metalloprotease-13.
Chondrocytes from patients with osteoarthritis express typical extracellular matrix molecules once grown onto a three-dimensional hyaluronan-based scaffold.
Expression pattern and circulating levels of endostatin in patients with pancreas cancer.
Ecto-5'-nucleotidase (CD73) -mediated extracellular adenosine production plays a critical role in hepatic fibrosis.
Chondrocyte hypertrophy and apoptosis induced by GROalpha require three-dimensional interaction with the extracellular matrix and a co-receptor role of chondroitin sulfate and are associated with the mitochondrial splicing variant of cathepsin B.
Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase Cdelta pathways in human adult articular chondrocytes.
The inhibition of subchondral bone resorption in the early phase of experimental dog osteoarthritis by licofelone is associated with a reduction in the synthesis of MMP-13 and cathepsin K.
Orgaz JL, Pandya P, Dalmeida R, Karagiannis P, Sanchez-Laorden B, Viros A, Albrengues J, Nestle FO, Ridley AJ, Gaggioli C, Marais R, Karagiannis SN, Sanz-Moreno V
Nature communications 2014 Jun 25;5:4255
Nature communications 2014 Jun 25;5:4255
Toll-like receptor 9 ligands enhance mesenchymal stem cell invasion and expression of matrix metalloprotease-13.
Nurmenniemi S, Kuvaja P, Lehtonen S, Tiuraniemi S, Alahuhta I, Mattila RK, Risteli J, Salo T, Selander KS, Nyberg P, Lehenkari P
Experimental cell research 2010 Oct 1;316(16):2676-82
Experimental cell research 2010 Oct 1;316(16):2676-82
Chondrocytes from patients with osteoarthritis express typical extracellular matrix molecules once grown onto a three-dimensional hyaluronan-based scaffold.
Cavallo C, Desando G, Facchini A, Grigolo B
Journal of biomedical materials research. Part A 2010 Apr;93(1):86-95
Journal of biomedical materials research. Part A 2010 Apr;93(1):86-95
Expression pattern and circulating levels of endostatin in patients with pancreas cancer.
Ohlund D, Ardnor B, Oman M, Naredi P, Sund M
International journal of cancer 2008 Jun 15;122(12):2805-10
International journal of cancer 2008 Jun 15;122(12):2805-10
Ecto-5'-nucleotidase (CD73) -mediated extracellular adenosine production plays a critical role in hepatic fibrosis.
Peng Z, Fernandez P, Wilder T, Yee H, Chiriboga L, Chan ES, Cronstein BN
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 Jul;22(7):2263-72
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 Jul;22(7):2263-72
Chondrocyte hypertrophy and apoptosis induced by GROalpha require three-dimensional interaction with the extracellular matrix and a co-receptor role of chondroitin sulfate and are associated with the mitochondrial splicing variant of cathepsin B.
Olivotto E, Vitellozzi R, Fernandez P, Falcieri E, Battistelli M, Burattini S, Facchini A, Flamigni F, Santi S, Facchini A, Borzi' RM
Journal of cellular physiology 2007 Feb;210(2):417-27
Journal of cellular physiology 2007 Feb;210(2):417-27
Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase Cdelta pathways in human adult articular chondrocytes.
Im HJ, Muddasani P, Natarajan V, Schmid TM, Block JA, Davis F, van Wijnen AJ, Loeser RF
The Journal of biological chemistry 2007 Apr 13;282(15):11110-21
The Journal of biological chemistry 2007 Apr 13;282(15):11110-21
The inhibition of subchondral bone resorption in the early phase of experimental dog osteoarthritis by licofelone is associated with a reduction in the synthesis of MMP-13 and cathepsin K.
Pelletier JP, Boileau C, Brunet J, Boily M, Lajeunesse D, Reboul P, Laufer S, Martel-Pelletier J
Bone 2004 Mar;34(3):527-38
Bone 2004 Mar;34(3):527-38
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