67398-1-Ig

antibody from Proteintech Group

Targeting: CASP4 ICE(rel)II, ICH-2, TX

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

67398-1-Ig

Provider

Proteintech Group

Product name

Caspase 4 antibody

Antibody type

Monoclonal

Description

Caspase 4 antibody (Cat. #67398-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1D1E12

Vial size

20ul, 150ul

References

Submitted references

Irradiated Tumor Cell-Derived Microparticles Activate Systemic Anti-Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils.

Hu Y, Wang J, Che M, Yang Z, Meng J, Yang X, Deng Y, Zhou Z, Wang Y, Wei W, Zhang Z, Wu B, Qin Y, Yang K, Jin H, Huang F, Sun Y, Wen L, Wan C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e14390

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HMGB1 impairs nasal mucosa epithelial barrier function in allergic rhinitis by promoting BECN1-mediating autophagy.

Ma Z, Tu L, Yang X, Mao M, Chen G, Chen F, Liao L, Xu Y
Biochemistry and biophysics reports 2025 Dec;44:102351

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Cardiolipin inhibits the non-canonical inflammasome by preventing LPS binding to caspase-4/11.

Pizzuto M, Monteleone M, Burgener SS, Began J, Kurera M, Chia JR, Frampton E, Crawford J, Oliveira M, Kenney KM, Coombs JR, Yamamoto M, Man SM, Broz P, Pelegrin P, Schroder K
The EMBO journal 2025 Aug;44(16):4419-4442

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Pyroptosis-related gene GSDMC indicates poor prognosis and promotes tumor progression by activating the AKT/mTOR pathway in lung squamous cell carcinoma.

Zhang Y, Wang Y, Weng J, Chen J, Zheng Y, Xia Y, Huang Z, Zhao L, Chen X, Tang H, Huang Y
Molecular carcinogenesis 2024 Nov;63(11):2218-2236

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Hypoxanthine Produces Rapid Antidepressant Effects by Suppressing Inflammation in Serum and Hippocampus.

Wu L, Chen J, Yu Q, Lu C, Shu Y
ACS chemical neuroscience 2024 Nov 6;15(21):3970-3980

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Caspase-4 dimerisation and D289 auto-processing elicit an interleukin-1β-converting enzyme.

Chan AH, Burgener SS, Vezyrgiannis K, Wang X, Acklam J, Von Pein JB, Pizzuto M, Labzin LI, Boucher D, Schroder K
Life science alliance 2023 Oct;6(10)

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Pyroptosis: a novel signature to predict prognosis and immunotherapy response in gliomas.

He G, Chen Z, Zhuo S, Tang J, Hao W, Yang K, Yang C
Human cell 2022 Nov;35(6):1976-1992