Tissue expression
Cell line expression
Protein structure

CASP4

Caspase 4
ICE(rel)II, ICH-2, TX 
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
More gene data

All Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antigen sequence

Epitope

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
826 antibodies from 43 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
2 antibodies
antibodies-online
193 antibodies
Invitrogen Antibodies
28 antibodies
NSJ Bioreagents
4 antibodies
Boster Biological Technology
3 antibodies
Biorbyt
106 antibodies
Novus Biologicals
47 antibodies
Acris Antibodies GmbH
20 antibodies
Arigo
4 antibodies
OriGene
21 antibodies
Cusabio Biotech Co., Ltd
8 antibodies
Aviva Systems Biology
12 antibodies
Enzo Life Sciences
4 antibodies
GeneTex
13 antibodies
St John's Laboratory
7 antibodies
FineTest Biotech
1 antibody
Signalway Antibody LLC
1 antibody
Abnova Corporation
9 antibodies
ProSci
5 antibodies
Abgent
8 antibodies
Affinity Biosciences
2 antibodies
NovoPro Bioscience Inc.
1 antibody
Atlas Antibodies
1 antibody
Bioworld Technology, Inc
2 antibodies
Everest Biotech
1 antibody
Antibodies.com
1 antibody
QED Bioscience
1 antibody
Abbkine Scientific Co.Ltd.
3 antibodies
Creative Biolabs
16 antibodies
MyBioSource
16 antibodies
RabMAbs
4 antibodies
Creative Diagnostics
6 antibodies
Abbexa
13 antibodies
Leading Biology
5 antibodies
Abbiotec
1 antibody
Cell Signaling Technology, Inc
1 antibody
United States Biological
41 antibodies
GenWay
8 antibodies
RayBiotech, Inc.
6 antibodies
MilliporeSigma / Merck KGaA
6 antibodies
Rockland Immunochemicals, Inc.
2 antibodies