ABIN319134

antibody from antibodies-online

Targeting: CASP5 ICE(rel)III

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

ABIN319134

Provider

antibodies-online

Product name

anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) antibody

Antibody type

Polyclonal

Antigen

A 14 amino acid peptide from the centre of human Caspase-5.

Description

Antisera to human Caspase-5 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

50 μg

Concentration

1.0 mg/mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma.

Lin XY, Choi MS, Porter AG
The Journal of biological chemistry 2000 Dec 22;275(51):39920-6

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Caspases: the executioners of apoptosis.

Cohen GM
The Biochemical journal 1997 Aug 15;326 ( Pt 1):1-16

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Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE.

Wang S, Miura M, Jung Yk, Zhu H, Gagliardini V, Shi L, Greenberg AH, Yuan J
The Journal of biological chemistry 1996 Aug 23;271(34):20580-7

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Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases.

Munday NA, Vaillancourt JP, Ali A, Casano FJ, Miller DK, Molineaux SM, Yamin TT, Yu VL, Nicholson DW
The Journal of biological chemistry 1995 Jun 30;270(26):15870-6