Tissue expression
Cell line expression

CASP5

gene product
ICE(rel)III 
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]
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550 antibodies from 39 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
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antibodies-online
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8 antibodies
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5 antibodies
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NSJ Bioreagents
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HUABIO Research
1 antibody
GeneTex
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Affinity Biosciences
2 antibodies
LifeSpan BioSciences, Inc.
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8 antibodies
Arigo
1 antibody
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Cell Signaling Technology, Inc
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RabMAbs
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ProSci
4 antibodies
Creative Diagnostics
8 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Bioworld Technology, Inc
2 antibodies
MyBioSource
10 antibodies
Rockland Immunochemicals, Inc.
3 antibodies
Atlas Antibodies
1 antibody
United States Biological
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Abbexa
11 antibodies
Leading Biology
4 antibodies
Abbiotec
2 antibodies
Proteintech Group
1 antibody
RayBiotech, Inc.
3 antibodies
GenWay
8 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
Exalpha Biologicals, Inc.
2 antibodies
EMD Millipore
1 antibody
Creative Biolabs
5 antibodies