CASP5

gene product
ICE(rel)III
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]
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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
22 antibodies
antibodies-online
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Biorbyt
25 antibodies
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Abgent
7 antibodies
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Boster Biological Technology
3 antibodies
NSJ Bioreagents
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LifeSpan BioSciences, Inc.
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2 antibodies
Aviva Systems Biology
8 antibodies
Arigo
1 antibody
Abnova Corporation
5 antibodies
Rockland Immunochemicals, Inc.
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Cell Signaling Technology, Inc
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RabMAbs
2 antibodies
ProSci
4 antibodies
Creative Biolabs
11 antibodies
Creative Diagnostics
8 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Bioworld Technology, Inc
2 antibodies
MyBioSource
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Atlas Antibodies
1 antibody
United States Biological
65 antibodies
St John's Laboratory
2 antibodies
Abbiotec
2 antibodies
RayBiotech, Inc.
3 antibodies
GenWay
8 antibodies
Sigma-Aldrich
3 antibodies
Exalpha Biologicals, Inc.
2 antibodies
EMD Millipore
1 antibody
Abbexa
3 antibodies