POLR1B

Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]). [supplied by OMIM, Mar 2008]

Description

RNA polymerase I subunit B

Protein family

Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Peptideatlas), RNA polymerase related proteins

Chromosome

2:q14.1 (112541915 - 112579818)

Ensembl ID

ENSG00000125630  (ver. 99.38)

Orthologs

Mouse Polr1b: ENSMUSG00000027395

UniProt

Q9H9Y6

neXtProt

NX_Q9H9Y6

Human splice variants
Mouse splice variants