Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- A03637 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Prostate Apoptosis Response Protein-4 PAWR Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for PAR4/PAWR detection. Host: Rabbit.Size: 100μl. Tested applications: IHC. Reactive species: Human. PAR4/PAWR information: Molecular Weight: 36568 MW; Subcellular Localization: Cytoplasm. Nucleus. Mainly cytoplasmic in absence of apoptosis signal and in normal cells. Nuclear in most cancer cell lines. Nuclear entry seems to be essential but not sufficient for apoptosis (By similarity). Nuclear localization includes nucleoplasm and PML nuclear bodies; Tissue Specificity: Widely expressed. Expression is elevated in various neurodegenerative diseases such as amyotrophic lateral sclerosis, Alzheimer, Parkinson and Huntington diseases and stroke. Down-regulated in several cancers.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μl
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- Store at -20°C for one year, at 4°C for one month. We suggest the antibody be aliquoted into small vials and stored frozen at -20°C upon receiving. Avoid repeated freezing and thawing.
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Supportive validation
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- Boster Biological Technology (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from 293 cells(Lane 2), using Prostate Apoptosis Response Protein-4 antiobdy A03637. The lane on the left is treated with synthesized peptide.
- Additional image