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LIG1
DNA ligase 1This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Top validated antibodies |
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| Novus Biologicals |  NB100-119 |
27 references | Monoclonal |
WB
ICC
IP
RA
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| antibodies-online | ABIN1526063 |
Monoclonal |
WB
ICC
IP
IHC
FC
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| Acris Antibodies GmbH | AM26565AF-N |
Monoclonal |
WB
ICC
IP
IHC
FC
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| Invitrogen Antibodies | 18051-1-AP |
Polyclonal |
WB
IP
IHC
OA
|
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| Proteintech Group | 18051-1-AP |
Polyclonal |
WB
EL
IP
IHC
|
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