Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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Comment
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- Product number
- ABIN499535 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Caspase Recruitment Domain Family, Member 8 (CARD8) antibody
- Antibody type
- Polyclonal
- Antigen
- Human CARD8 / Cardinal / TUCAN Peptide (AP30184°CP-N)
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C.
Submitted references TUCAN/CARDINAL and DRAL participate in a common pathway for modulation of NF-kappaB activation.
CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis.
TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer.
DRAL is a p53-responsive gene whose four and a half LIM domain protein product induces apoptosis.
Stilo R, Leonardi A, Formisano L, Di Jeso B, Vito P, Liguoro D
FEBS letters 2002 Jun 19;521(1-3):165-9
FEBS letters 2002 Jun 19;521(1-3):165-9
CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis.
Razmara M, Srinivasula SM, Wang L, Poyet JL, Geddes BJ, DiStefano PS, Bertin J, Alnemri ES
The Journal of biological chemistry 2002 Apr 19;277(16):13952-8
The Journal of biological chemistry 2002 Apr 19;277(16):13952-8
TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer.
Pathan N, Marusawa H, Krajewska M, Matsuzawa S, Kim H, Okada K, Torii S, Kitada S, Krajewski S, Welsh K, Pio F, Godzik A, Reed JC
The Journal of biological chemistry 2001 Aug 24;276(34):32220-9
The Journal of biological chemistry 2001 Aug 24;276(34):32220-9
DRAL is a p53-responsive gene whose four and a half LIM domain protein product induces apoptosis.
Scholl FA, McLoughlin P, Ehler E, de Giovanni C, Schäfer BW
The Journal of cell biology 2000 Oct 30;151(3):495-506
The Journal of cell biology 2000 Oct 30;151(3):495-506
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of CARD8 expression in K562 cell lysate with AP30184PU-N CARD8 antibody at (A) 2 and (B) 4 ?g /ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of CARD8 in K562 cells with AP30184PU-N CARD8 antibody at 10 ?g/ml.