CARD8

gene product
CARDINAL, Dakar, KIAA0955, NDPP, TUCAN
The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
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295 antibodies from 31 providers.

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Novus Biologicals
8 antibodies
antibodies-online
108 antibodies
Abnova Corporation
8 antibodies
Acris Antibodies GmbH
6 antibodies
Atlas Antibodies
2 antibodies
LifeSpan BioSciences, Inc.
38 antibodies
Invitrogen Antibodies
6 antibodies
Biorbyt
14 antibodies
Affinity Biosciences
1 antibody
Boster Biological Technology
1 antibody
NovoPro Bioscience Inc.
1 antibody
OriGene
6 antibodies
GeneTex
4 antibodies
Rockland Immunochemicals, Inc.
1 antibody
Bioworld Technology, Inc
1 antibody
Abgent
3 antibodies
ProSci
1 antibody
Proteintech Group
1 antibody
Creative Biolabs
10 antibodies
MyBioSource
5 antibodies
Arigo
1 antibody
Aviva Systems Biology
1 antibody
United States Biological
45 antibodies
Abbexa
1 antibody
RabMAbs
1 antibody
St John's Laboratory
1 antibody
Sigma-Aldrich
3 antibodies
Creative Diagnostics
2 antibodies
RayBiotech, Inc.
2 antibodies
GenWay
1 antibody