Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B10571 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human LITAF monoclonal antibody, clone BU2G0
- Antibody type
- Monoclonal
- Description
- Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Pagets disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2014]
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- BU2G0
- Vial size
- 100 _l
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
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