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Protein structure
ABCD4
ATP binding cassette subfamily D member 4EST352188, P70R, PMP69, PXMP1L
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in several protein-coding and non-protein-coding variants. [provided by RefSeq, Jul 2017]
Top validated antibodies |
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| Acris Antibodies GmbH |  AP50020PU-N |
Polyclonal |
WB
EL
IHC
FC
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| Affinity Biosciences | DF3814 |
Polyclonal |
WB
EL
ICC
IHC
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| GeneTex | GTX114690 |
Polyclonal |
WB
ICC
IHC
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| LSBio | LS-B11429 |
Polyclonal |
WB
EL
IHC
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| Biorbyt | orb155557 |
Polyclonal |
WB
EL
ICC
IHC
|
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