CABT-BL4895

antibody from Creative Diagnostics

Targeting: IBTK BTBD26, BTKI, DKFZP564B116

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-BL4895

Provider

Creative Diagnostics

Product name

Anti-IBTK (aa 589-617) polyclonal antibody

Antibody type

Polyclonal

Description

Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTKs kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 _g

Storage

Store at 4°C (up to 6 months). For long term storage store at -20°C