27155-1-AP

antibody from Proteintech Group

Targeting: CASP7 CMH-1, ICE-LAP3, MCH3

Provider product page for 27155-1-AP

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Immunoprecipitation

Antibody data

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Product number: 27155-1-AP - Provider product page
Provider: Proteintech Group
Product name: Caspase 7/p20 antibody
Antibody type: Polyclonal
Description: KD/KO validated Caspase 7/p20 antibody (Cat. #27155-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IP, WB,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

CASP7 protein structure - 27155-1-AP shown in red.

Submitted references Reactive oxygen species/hypoxia dual-responsive polymers combined with melatonin inhibited PANoptosis of retinal ganglion cells for acute glaucoma treatment.

Meng S, Fang W, Wu Y, Xia Z, Chou T, Xia Y, Ding L, Zhou X, Xia X
Theranostics 2026;16(2):830-851

Targeting methionine-induced pyroptosis enhances anti-tumor immunity.

Lei M, Zhu W, Wang C, Zhang F, Li M, Zhang Y, Qu J, Luo Z, Li J, Li ZX, Yin M, Lei QY
Science China. Life sciences 2026 May;69(5):1604-1619

Febrifugine dihydrochloride restricts porcine epidemic diarrhea virus replication by modulating the IGF1R-driven PI3K/AKT-apoptosis axis.

Yan P, Kyaw ZO, Wang X, Li N, Xu Y, Gao S, Huan C
Journal of virology 2026 May 19;100(5):e0011726

INHBB promotes liver metastasis of colorectal cancer via regulation of TGF-β/Smad signaling, EMT and anoikis resistance.

Yang N, Dai D, Zhao J, Zhao H, Jiang H, Liu J, Liu F, Chen X
Tissue & cell 2026 Apr;99:103258

Integrative analysis and experimental validation unveil TNFSF10 as a key PANoptosis inducer driving preeclampsia pathogenesis.

Mei Z, Li L, Chen J, Yang S, Li Y, Li X, Li M, Chen M, Kong R, Zhao Y, Zhao K, McClements L, Zhang H, Liu C
International immunopharmacology 2026 Apr 15;175:116401

Tubeimoside I Inhibits the Proliferation of Liver Cancer Through Inactivating NF-κB Pathway by Regulating TNFAIP3 Expression.

Zhang Y, Zhou M, Zhu L, Chen L, Zhang H, Huang Z, Zhou H
Drug design, development and therapy 2025;19:1895-1908

ER-α36 prevents high glucose-induced cellular senescence and apoptosis in renal tubular cell.

Yu D, Luo L, Liang Y, Zhou H, Xiao Y, An X, Wang Y, Xu Z, Sun W, Wang W
Frontiers in endocrinology 2025;16:1426854

ESCO2 inhibition induces cell cycle arrest and apoptosis in breast cancer via the P53-CDK1 axis and the BAX/Bcl2/caspase signaling cascade.

Li P, Wei L, Li M, Liu X, Yang H
Frontiers in oncology 2025;15:1585945

β-elemene promotes ferroptosis to improve the sensitivity of imatinib in gastrointestinal stromal tumours by targeting N6AMT1.

Lan J, Zhang W, Zeng K, Li C, He J, Li X, Yang R, Chi J, Hong Z, Wang W, Zhou C, Xiao B, Fan W, Lin J, Ou Q, Fang Y, Pan Z, Peng J, Li W, Wu X
Clinical and translational medicine 2025 Sep;15(9):e70438

MiRNA-634 promotes apoptosis in HEI-OC1 cells by regulating AK4 and AKT/mTOR signaling pathways.

Wang Y, Liu Y
Hearing research 2025 Oct;466:109386

Radioprotective Efficacy of Jujube Aqueous Extract and Arbutin: Synergistic Antioxidant and Anti-Apoptotic Mechanisms in Radiation Injury.

Wang L, Yang H, Zhou X, Zhao Y, Li L, Wang N
Food science & nutrition 2025 Oct;13(10):e71073

BCL-2 Inhibitor Regulates Number, Function, and Antitumor Immunity of T Cells by Influencing Glycolysis in AML.

Peng X, Li Y, Tang F, Ma Y, Bai J, Li L, Zhang L
Cancer science 2025 Oct;116(10):2657-2676

A novel non-nad-based PARP1 inhibitor, Japoflavone B, triggered Caspase-3/GSDME-mediated pyroptosis through ROS/p38/p53 pathway in NSCLC.

Wan H, Wei J, Wang Y, Ge L, Hu Q, Li Y, Zhou B, Zeng X
Chemico-biological interactions 2025 Oct 22;420:111693

Panoptosis Targets the Mechanism of PRDX1 Involvement in Acute Myocardial Infarction via ZBP1.

Sun Y, Ji C, Zhang Y, Liu S, Ye Y, Li T, Wu S, Sun T, Yin H, Yan W, Jin W
Journal of cellular biochemistry 2025 Mar;126(3):e70026

Charged multivesicular body protein 4C promotes the progression of cervical cancer through the HPV E6/miR‑543 axis.

Liu RC, Ji YM, Huang J, Du YP, Zhong YM, Sheng XJ
Oncology letters 2025 Jun;29(6):275

Exploration of the Potential Bioactive Compounds and Functional Mechanism of Chaihu Sanshen Capsule in Ameliorating Myocardial Ischaemia-Reperfusion Injury: A Serum Pharmaco-Chemistry With Network Pharmacology Analysis.

Wang W, Zhang Z, Liu R, Zheng Y, Hu Y, Li X, Shen Z, Yuan H, Liu J
Journal of cellular and molecular medicine 2025 Jul;29(14):e70666

Discovery of TNI-97 as a Highly Selective, Orally Bioavailable HDAC6 Inhibitor for the Treatment of Triple-Negative Breast Cancer.

Wang S, Luo M, Xu Q, Guo R, Zhang W, Li B, Qin H, Wei L, Cui Y, Sha J, Shao S, Yu X, Zhao L, Sun P, Bai C, Wen J, Liu D
Journal of medicinal chemistry 2025 Jul 24;68(14):14333-14356

IDO1 inhibits ferroptosis by regulating FTO-mediated m6A methylation and SLC7A11 mRNA stability during glioblastoma progression.

Tian Q, Dan G, Wang X, Zhu J, Chen C, Tang D, Wang Z, Chen D, Lei S, Yang C, Wang H, Guo B, Jin B, Chen T, Tang L
Cell death discovery 2025 Jan 25;11(1):22

Delactylation diminished the growth inhibitory role of CA3 by restoring DUOX2 expression in hepatocellular carcinoma.

Yan J, Zhou Y, Xu J, Dong Y, Yang X, Yang X, Wu A, Chang S, Wang Y, Zhang Q, Ayaka T, Yu L, Zhao L, Meng H, Liu D
Experimental cell research 2025 Jan 15;444(2):114392

Inhibitory effects of the combination of rapamycin with gemcitabine plus paclitaxel on the growth of pancreatic cancer tumors.

Jobu Y, Nishigawa M, Furihata K, Furihata M, Uchida K, Taniuchi K
Human cell 2025 Jan 11;38(2):44

Inhibition Effects and Mechanism Study of rAj-HRP30, a Recombinant Histidine-Rich Peptide from Apostichopus japonicus, on the Viability of Pancreatic Ductal Adenocarcinoma Cells Panc01 and Panc02.

Song Y, Gao S, Jiang J, Zhang Y, Zhang J, Wang X, Lv L, Zhou Z, Wang J
International journal of molecular sciences 2025 Feb 11;26(4)

Dietary cholesterol impairs cognition via gut microbiota-derived deoxycholic acid in obese mice.

Liu Y, Wang Z, Zhang Y, Zhao T, Zhang Q, Huang W, Lu B
Gut microbes 2025 Dec;17(1):2537753

Porcine cGAS-STING signalling induced apoptosis negatively regulates STING downstream IFN response and autophagy via different mechanisms.

Xia N, Liu A, Han H, Jiang S, Cao Q, Luo J, Zhang J, Hao W, Sun Z, Chen N, Zhang H, Zheng W, Zhu J
Virulence 2025 Dec;16(1):2496436

Mechanism of lncRNA WARS2-IT1 promoting angiogenesis of glioma through miR-299-3P/VEGFA axis and activating PI3K/AKT signaling pathway.

Hu M, Gu W, Huai Y, Wang C, Mei J
Cytotechnology 2025 Aug;77(4):157

Leber's hereditary optic neuropathy-associated ND1 3733G>C mutation ameliorates the mitochondrial quality control and cellular homeostasis.

Yasheng M, Ji Y, He Y, Yi Q, Zhang H, Shan W, Wang K, Zhang J, Li Y, Meng F, Zhang M, Mo JQ, Wei S, Guan MX
The Journal of biological chemistry 2025 Aug;301(8):110464

Circulating metabolomics reveals guanosine monophosphate synthetase (GMPS) as a novel therapeutic target in lung adenocarcinoma.

Yu M, Yang D, Zhu D, Wang Y, Cao M, Zhu J, Zhu W, Wang G, Aa J
The Journal of pathology 2025 Aug;266(4-5):465-480

Yeast culture in weaned lamb feed: a proteomic journey into enhanced rumen health and growth.

Li X, Yang X, Chen H, Liu S, Hao P, Ning J, Wu Y, Liang X, Zhang Y, Liu D
Journal of animal science and biotechnology 2025 Aug 1;16(1):107

Molecular mechanisms of antiproliferative and pro-apoptotic effects of essential oil active constituents in MCF7 and T24 cancer cell lines: in vitro insights and in silico modelling of proapoptotic gene product-compound interactions.

Saini D, Chaudhary PK, Chaudhary JK, Kaur H, Verma GK, Pramanik SD, Roy P, Mirza-Shariff AA, Prasad R
Apoptosis : an international journal on programmed cell death 2025 Apr;30(3-4):805-825

Structurally diverse tetrahydroxanthone analogues from Paraconiothyrium sp. AC31 with pyroptosis induction through targeted inhibition of PARP1 in hepatocellular carcinoma cells.

Zhang MK, Hu QQ, He LM, Li M, Chen WC, Zhu KK, Yuan RY, Wu XY, Gao P, Zeng XB, Cai YS
Bioorganic chemistry 2025 Apr;157:108310

Synthesis and biological evaluation of novel isatin-phenol hybrids as potential antitumor agents.

Chen Z, Guo Y, Peng Y, Tan X, Chen H, Luo D, Luo K, Wu D, Huang Z, Yu Z, Tao C
Bioorganic chemistry 2025 Apr;157:108232

Targeted Regulation of HSP70 by the ARP2/3 Complex in Mammary Epithelial Cells and Its Impact on Host Cell Apoptosis.

Yang T, Fang B, Chen Y, Bao D, Zhang J, Liu P, Duan Z, He Y, Zhao X, Zhang QW, Dong WT, Zhang Y
Biomolecules 2025 Apr 7;15(4)

Mitigating inflammation and fibrosis: the therapeutic potential of quercetin liposomes in COPD.

Yin C, Tian Y, Yan A, Wang H, Lu F, Li X, Li X, Han S, Miao R, Chen H, Li D, Hou H, Hu Q
Frontiers in pharmacology 2024;15:1503283

Caspase-mediated AURKA cleavage at Asp(132) is essential for paclitaxel to elicit cell apoptosis.

Chen X, Du S, Zhang Y, Peng K, Liu L, Wang T, Zhang H, Cai S, Zhu C, Li Y, Tuo W, Wang Y, Wei F, Cai Q
Theranostics 2024;14(10):3909-3926

Neoadjuvant immunotherapy plus chemotherapy for squamous cell carcinoma of the paranasal sinus: a case report.

Sun Y, Yang G, Sun R, Cao F
Frontiers in oncology 2024;14:1462993

Bimetallic peroxide nanoparticles induce PANoptosis by disrupting ion homeostasis for enhanced immunotherapy.

Hou G, Chen Y, Lei H, Lu Y, Liu L, Han Z, Sun S, Li J, Cheng L
Science advances 2024 Nov 8;10(45):eadp7160

Selective Organ-Targeting Hafnium Oxide Nanoparticles with Multienzyme-Mimetic Activities Attenuate Radiation-Induced Tissue Damage.

Liu D, Cao F, Xu Z, Zhao C, Liu Z, Pang J, Liu ZX, Moghiseh M, Butler A, Liang S, Fan W, Yang J
Advanced materials (Deerfield Beach, Fla.) 2024 May;36(19):e2308098

TH-4000, a hypoxia-activated pan-HER inhibitor, shows excellent preclinical efficacy for the treatment of HER2(+) breast cancer.

Shao X, Yang D, Shan L, Yan X, Xu D, Li L, Sun Y, Yu Q, Zhou H, Ding Y, Tang J
Archives of toxicology 2024 Mar;98(3):865-881

Effect of lipopolysaccharide on TAK1-mediated hepatocyte PANoptosis through Toll-like receptor 4 during acute liver failure.

Li W, Zhang W, Zhang D, Shi C, Wang Y
International immunopharmacology 2024 Mar 10;129:111612

Design, synthesis and biological evaluation of indoline-maleimide conjugates as potential antitumor agents for the treatment of colorectal cancer.

Tang J, Zhang Y, Zhou L, Song X, Wei Y, Qi J, Wu J, Song Z, Zhan L
Bioorganic & medicinal chemistry 2024 Jun 15;108:117786

Arsenic-induced downregulation of BRWD3 suppresses proliferation and induces apoptosis in lung adenocarcinoma cells through the p53 and p65 pathways.

Zhu Y, Xiao M, Zhao R, Yang X, Wu K, Liu X, Chen X, Guo L, Liu J, Chen X, Liu N, He Y, Zhang Y
Human & experimental toxicology 2024 Jan-Dec;43:9603271241279166

Wnt/β-catenin signalling activates IMPDH2-mediated purine metabolism to facilitate oxaliplatin resistance by inhibiting caspase-dependent apoptosis in colorectal cancer.

Huang Y, Chan S, Chen S, Liu X, Li M, Zheng L, Dong Z, Yang Z, Liu Z, Zhou D, Zhang X, Zhang B
Journal of translational medicine 2024 Feb 3;22(1):133

Pasteurella multocida activates apoptosis via the FAK-AKT-FOXO1 axis to cause pulmonary integrity loss, bacteremia, and eventually a cytokine storm.

Zhao G, Tang Y, Dan R, Xie M, Zhang T, Li P, He F, Li N, Peng Y
Veterinary research 2024 Apr 8;55(1):46

Identification of molecular subtypes based on PANoptosis-related genes and construction of a signature for predicting the prognosis and response to immunotherapy response in hepatocellular carcinoma.

Zhu J, Huang Q, Peng X, Luo C, Liu Z, Liu D, Yuan H, Yuan R, Cheng X
Frontiers in immunology 2023;14:1218661

Choroidal circulation disturbance is an initial factor in outer retinal degeneration in rats under simulated weightlessness.

Mu Y, Wei D, Yao L, Xu X, Li S, Cao R, Chen T, Zhang Z
Frontiers in physiology 2023;14:1198862

A novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of nonalcoholic steatohepatitis.

Guo Q, Xin M, Lu Q, Feng D, Yang V, Peng LF, Whelan KA, Hu W, Wu S, Yang X, Wang H, Rothberg BS, Gamero AM, Gerhard GS, Gao B, Yang L
Theranostics 2023;13(7):2210-2225

HSP90B1-mediated plasma membrane localization of GLUT1 promotes radioresistance of glioblastomas.

Li Y, Ge Y, Zhao M, Ding F, Wang X, Shi Z, Ge X, Wang X, Qian X
Journal of biomedical research 2023 Sep 28;37(5):326-339

Targeting HSP90 with picropodophyllin suppresses gastric cancer tumorigenesis by disrupting the association of HSP90 and AKT.

Li X, Wang G, Zhou X, Zhao H, Chen X, Cui Q, Li M, Gao X, Wei X, Ye L, Li D, Hong P
Phytotherapy research : PTR 2023 Oct;37(10):4740-4754

Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation.

Ge Z, Xu M, Ge Y, Huang G, Chen D, Ye X, Xiao Y, Zhu H, Yin R, Shen H, Ma G, Qi L, Wei G, Li D, Wei S, Zhu M, Ma H, Shi Z, Wang X, Ge X, Qian X
Cell reports 2023 Nov 28;42(11):113417

p52-ZER6: a determinant of tumor cell sensitivity to MDM2-p53 binding inhibitors.

Li WF, Alfason L, Huang C, Tang Y, Qiu L, Miyagishi M, Wu SR, Kasim V
Acta pharmacologica Sinica 2023 Mar;44(3):647-660

Cytotoxic steroidal glycosides from the rhizomes of Paris polyphylla var. yunnanensis.

Liu Y, Liu MY, Bi LL, Tian YY, Qiu PC, Qian XY, Wang MC, Tang HF, Lu YY, Zhang BL
Phytochemistry 2023 Mar;207:113577

GSDMD knockdown exacerbates hippocampal damage and seizure susceptibility by crosstalk between pyroptosis and apoptosis in kainic acid-induced temporal lobe epilepsy.

Lin A, Guo Y, Zhang H, Lin P, Tao K, Jiang L, Xu D, Chen B
Biochimica et biophysica acta. Molecular basis of disease 2023 Jun;1869(5):166687

Proteasomal inhibitors induce myeloma cell pyroptosis via the BAX/GSDME pathway.

Liang JP, He YM, Cui YL, Sun YN, He GS, Zhu ZG, Mao XL
Acta pharmacologica Sinica 2023 Jul;44(7):1464-1474

Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.

Hu M, Li T, Ma X, Liu S, Li C, Huang Z, Lin Y, Wu R, Wang S, Lu D, Lu T, Men X, Shen S, Huang H, Liu Y, Song K, Jian B, Jiang Y, Qiu W, Liu Q, Lu Z, Cai W
Nature communications 2023 Jul 4;14(1):3945

6-Methoxydihydrosanguinarine induces apoptosis and autophagy in breast cancer MCF-7 cells by accumulating ROS to suppress the PI3K/AKT/mTOR signaling pathway.

Zhang L, Zhang X, Che D, Zeng L, Zhang Y, Nan K, Zhang X, Zhang H, Guo Z
Phytotherapy research : PTR 2023 Jan;37(1):124-139

METTL14-dependent maturation of pri-miR-17 regulates mitochondrial homeostasis and induces chemoresistance in colorectal cancer.

Sun K, Chen L, Li Y, Huang B, Yan Q, Wu C, Lai Q, Fang Y, Cai J, Liu Y, Chen J, Wang X, Zhu Y, Dong S, Tan J, Li A, Liu S, Zhang Y
Cell death & disease 2023 Feb 21;14(2):148

Towards Developing Novel Prostate Cancer Recurrence Suppressors: Acute Toxicity of Pseurotin A, an Orally Active PCSK9 Axis-Targeting Small-Molecule in Swiss Albino Mice.

McGehee OC, Ebrahim HY, Rad AH, Abdelwahed KS, Mudhish EA, King JA, Helal IE, Meyer SA, El Sayed KA
Molecules (Basel, Switzerland) 2023 Feb 2;28(3)

Ionizing Radiation Triggers the Antitumor Immunity by Inducing Gasdermin E-Mediated Pyroptosis in Tumor Cells.

Cao W, Chen G, Wu L, Yu KN, Sun M, Yang M, Jiang Y, Jiang Y, Xu Y, Peng S, Han W
International journal of radiation oncology, biology, physics 2023 Feb 1;115(2):440-452

Inorganic arsenic-mediated upregulation of TUG1 promotes apoptosis in human bronchial epithelial cells by activating the p53 signaling pathway.

Chen Q, Sun M, Cheng H, Qi J, Tan J, Gu Y, Yu T, Li M, Xu H, He Y, Wen W
Toxicology and industrial health 2023 Dec;39(12):700-711

Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule.

Lu D, Liu Y, Huang H, Hu M, Li T, Wang S, Shen S, Wu R, Cai W, Lu T, Lu Z
Translational stroke research 2023 Dec;14(6):910-928

Sinapine thiocyanate exhibited anti-colorectal cancer effects by inhibiting KRT6A/S100A2 axis.

Yang Y, Zeng Z, Li L, Lei S, Wu Y, Chen T, Zhang J
Cancer biology & therapy 2023 Dec 31;24(1):2249170

RCN2 promotes Nasopharyngeal carcinoma progression by curbing Calcium flow and Mitochondrial apoptosis.

Yao H, Zhang S, Xie H, Fan Y, Miao M, Zhu R, Yuan L, Gu M, You Y, You B
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):1031-1048

Oxoglutarate dehydrogenase-like inhibits the progression of hepatocellular carcinoma by inducing DNA damage through non-canonical function.

Jiang X, Peng J, Xie Y, Xu Y, Liu Q, Cheng C, Yan P, Xu S, Wang Y, Zhang L, Li H, Li Y, Li B, Han J, Yu D
Cell death and differentiation 2023 Aug;30(8):1931-1942

Sinapic Acid Alleviates Acute Pancreatitis in Association with Attenuation of Inflammation, Pyroptosis, and the AMPK/NF-[Formula: see text]B Signaling Pathway.

Huang ZW, Tan P, Yi XK, Chen H, Sun B, Shi H, Mou ZQ, Cheng YL, Li TX, Li Q, Fu WG
The American journal of Chinese medicine 2022;50(8):2185-2197

Aberrant Expression of BUB1B Contributes to the Progression of Thyroid Carcinoma and Predicts Poor Outcomes for Patients.

Yan HC, Xiang C
Journal of Cancer 2022;13(7):2336-2351

Lysophosphatidic acid suppresses apoptosis of high-grade serous ovarian cancer cells by inducing autophagy activity and promotes cell-cycle progression via EGFR-PI3K/Aurora-A(Thr288)-geminin dual signaling pathways.

Zhao H, Jia P, Nanding K, Wu M, Bai X, Morigen M, Fan L
Frontiers in pharmacology 2022;13:1046269

Harpagoside Protects Against Doxorubicin-Induced Cardiotoxicity via P53-Parkin-Mediated Mitophagy.

Li W, Wang X, Liu T, Zhang Q, Cao J, Jiang Y, Sun Q, Li C, Wang W, Wang Y
Frontiers in cell and developmental biology 2022;10:813370

TRIM36 inhibits tumorigenesis through the Wnt/β-catenin pathway and promotes caspase-dependent apoptosis in hepatocellular carcinoma.

Tong Q, Yi M, Kong P, Xu L, Huang W, Niu Y, Gan X, Zhan H, Tian R, Yan D
Cancer cell international 2022 Sep 6;22(1):278

chi-miR-99b-3p Regulates the Proliferation of Goat Skeletal Muscle Satellite Cells In Vitro by Targeting Caspase-3 and NCOR1.

Liao R, Lv Y, Dai J, Zhang D, Zhu L, Lin Y
Animals : an open access journal from MDPI 2022 Sep 11;12(18)

Derepression of the USP22-FASN axis by p53 loss under oxidative stress drives lipogenesis and tumorigenesis.

Han Z, Liu M, Xie Y, Zeng K, Zhan Z, Chen Y, Wang L, Chen X, Luo Y, Zeng Y, Zhan H, Lin Y, Zhang K, Zhu X, Liu S, Luo X, Zhou A
Cell death discovery 2022 Nov 4;8(1):445

The expression profile of lung long non-coding RNAs and mRNAs in a mouse model of smoke inhalation injury.

Jiang ZY, Liu MZ, Fu ZH, Liao XC, Xu B, Shi LL, Li JQ, Guo GH
Bioengineered 2022 Mar;13(3):4978-4990

Ubiquitin conjugating enzyme E2 C (UBE2C) may play a dual role involved in the progression of thyroid carcinoma.

Xiang C, Yan HC
Cell death discovery 2022 Mar 24;8(1):130

Hexachlorophene, a selective SHP2 inhibitor, suppresses proliferation and metastasis of KRAS-mutant NSCLC cells by inhibiting RAS/MEK/ERK and PI3K/AKT signaling pathways.

Fu NJ, Xi RY, Shi XK, Li RZ, Zhang ZH, Li LY, Zhang GL, Wang F
Toxicology and applied pharmacology 2022 Apr 15;441:115988

ATIC inhibits autophagy in hepatocellular cancer through the AKT/FOXO3 pathway and serves as a prognostic signature for modeling patient survival.

Zhang H, Xia P, Liu J, Chen Z, Ma W, Yuan Y
International journal of biological sciences 2021;17(15):4442-4458

Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.

Yang M, Li WY, Xie J, Wang ZL, Wen YL, Zhao CC, Tao L, Li LF, Tian Y, Sheng J
Frontiers in pharmacology 2021;12:639256

SNHG9, a Papillary Thyroid Cancer Cell Exosome-Enriched lncRNA, Inhibits Cell Autophagy and Promotes Cell Apoptosis of Normal Thyroid Epithelial Cell Nthy-ori-3 Through YBOX3/P21 Pathway.

Wen D, Liu WL, Lu ZW, Cao YM, Ji QH, Wei WJ
Frontiers in oncology 2021;11:647034

3-Epipachysamine B suppresses proliferation and induces apoptosis of breast cancer cell via PI3K/AKT/mTOR signaling pathway.

Zhang L, Zheng Y, Zeng L, Zhang F, Che D, Cao Z, Huang C, Xian L, Zhang X, Zhang H, Guo Z
Life sciences 2021 Nov 15;285:119995

GPR12 inhibits migration and promotes apoptosis in esophageal cancer and hypopharyngeal cancer cells.

Zhang M, Yang X, Chen S, Jia W, Ma X, Wang J, Qian Y, Lei D, Liu H, Pan X
Thoracic cancer 2021 May;12(10):1525-1535

Psychosocial and behavioral problems of children and adolescents in the early stage of reopening schools after the COVID-19 pandemic: a national cross-sectional study in China.

Wang L, Zhang Y, Chen L, Wang J, Jia F, Li F, Froehlich TE, Hou Y, Hao Y, Shi Y, Deng H, Zhang J, Huang L, Xie X, Fang S, Xu L, Xu Q, Guan H, Wang W, Shen J, Qian Y, Wang X, Shan L, Tan C, Yu Y, Wang X, Chen F, Zhang L, Li X, Shi X, Ke X, Li T
Translational psychiatry 2021 Jun 3;11(1):342

Self-assembled polymeric nanocarrier-mediated co-delivery of metformin and doxorubicin for melanoma therapy.

Song M, Xia W, Tao Z, Zhu B, Zhang W, Liu C, Chen S
Drug delivery 2021 Dec;28(1):594-606

Tianma Gouteng Decoction Exerts Cardiovascular Protection by Upregulating OPG and TRAIL in Spontaneously Hypertensive Rats.

Deng LH, Li L, Zhai Y, Michael S, Yang CY, Guo R, Chen SF, Fan GW, Zhao YQ, Liu W
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3439191

A novel antisense lncRNA NT5E promotes progression by modulating the expression of SYNCRIP and predicts a poor prognosis in pancreatic cancer.

Zhang P, Cao M, Zhang Y, Xu L, Meng F, Wu X, Xia T, Chen Q, Shi G, Wu P, Chen L, Lu Z, Yin J, Cai B, Cao S, Miao Y, Jiang K
Journal of cellular and molecular medicine 2020 Sep;24(18):10898-10912

Bismuth Porphyrin Antagonizes Cisplatin-Induced Nephrotoxicity via Unexpected Metallothionein-Independent Mechanisms.

Wang R, Wang S, Chan S, Wang Y, Zhang Y, Zuo Z, Chi-Fung Chan G, Li H, Sun H
iScience 2020 May 22;23(5):101054

Camellia oil (Camellia oleifera Abel.) attenuates CCl(4)-induced liver fibrosis via suppressing hepatocyte apoptosis in mice.

Lei X, Liu Q, Liu Q, Cao Z, Zhang J, Kuang T, Fang Y, Liu G, Qian K, Fu J, Du H, Liu Z, Xiao Z, Li C, Xu X
Food & function 2020 May 1;11(5):4582-4590

Long noncoding RNA UBE2R2-AS1 promotes glioma cell apoptosis via targeting the miR-877-3p/TLR4 axis.

Xu W, Hu GQ, Da Costa C, Tang JH, Li QR, Du L, Pan YW, Lv SQ
OncoTargets and therapy 2019;12:3467-3480

Regulation of host cell pyroptosis and cytokines production by Mycobacterium tuberculosis effector PPE60 requires LUBAC mediated NF-κB signaling.

Gong Z, Kuang Z, Li H, Li C, Ali MK, Huang F, Li P, Li Q, Huang X, Ren S, Li J, Xie J
Cellular immunology 2019 Jan;335:41-50

Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression.

Zhang Y, Li Q, Yu S, Zhu C, Zhang Z, Cao H, Xu J
Biochemical and biophysical research communications 2019 Feb 12;509(3):753-762

Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway.

Xu H, Li Y, Han B, Li Z, Wang B, Jiang P, Zhang J, Ma W, Zhou D, Li X, Ye X
Journal of agricultural and food chemistry 2018 Sep 19;66(37):9704-9718

RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma.

Wang X, Liu W, Wang P, Li S
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2018 Nov;47(10):930-937

Polybrominated Diphenyl Ethers Quinone Induced Parthanatos-like Cell Death through a Reactive Oxygen Species-Associated Poly(ADP-ribose) Polymerase 1 Signaling.

Dong W, Yang B, Wang Y, Yuan J, Fan Y, Song E, Song Y
Chemical research in toxicology 2018 Nov 19;31(11):1164-1171

Role of Daucosterol Linoleate on Breast Cancer: Studies on Apoptosis and Metastasis.

Han B, Jiang P, Liu W, Xu H, Li Y, Li Z, Ma H, Yu Y, Li X, Ye X
Journal of agricultural and food chemistry 2018 Jun 20;66(24):6031-6041

Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production.

Zhang W, Xiao D, Shan L, Zhao J, Mao Q, Xia H
Biotechnology and bioengineering 2017 Nov;114(11):2539-2549

Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways.

Gao Y, Xiao X, Zhang C, Yu W, Guo W, Zhang Z, Li Z, Feng X, Hao J, Zhang K, Xiao B, Chen M, Huang W, Xiong S, Wu X, Deng W
Journal of pineal research 2017 Mar;62(2)

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