CASP7

gene product
CMH-1, ICE-LAP3, MCH3
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
1015 antibodies from 40 providers.

Antibody properties

General

Applications

or Cancel
Antibody
GeneTex
13 antibodies
antibodies-online
357 antibodies
Novus Biologicals
31 antibodies
Enzo Life Sciences
4 antibodies
Abnova Corporation
23 antibodies
LifeSpan BioSciences, Inc.
166 antibodies
Affinity Biosciences
3 antibodies
Biorbyt
55 antibodies
Cell Signaling Technology, Inc
6 antibodies
OriGene
24 antibodies
Bioworld Technology, Inc
5 antibodies
Acris Antibodies GmbH
26 antibodies
Boster Biological Technology
5 antibodies
St John's Laboratory
7 antibodies
Aviva Systems Biology
11 antibodies
Abgent
12 antibodies
Arigo
3 antibodies
NSJ Bioreagents
2 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
R&D Systems
2 antibodies
Invitrogen Antibodies
16 antibodies
ProSci
5 antibodies
RabMAbs
4 antibodies
Abbkine Scientific Co.Ltd.
5 antibodies
Creative Diagnostics
5 antibodies
Creative Biolabs
41 antibodies
MyBioSource
17 antibodies
GenWay
11 antibodies
BioLegend
1 antibody
EMD Millipore
1 antibody
United States Biological
116 antibodies
RayBiotech, Inc.
9 antibodies
Abbiotec
1 antibody
Abiocode, Inc.
1 antibody
Sigma-Aldrich
4 antibodies
Exalpha Biologicals, Inc.
3 antibodies
eBioscience, An Affymetrix Company
2 antibodies
Active Motif
1 antibody
Abbexa
3 antibodies