Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 645301 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#645301, RRID:AB_2068003
- Product name
- Purified anti-Caspase-7
- Antibody type
- Monoclonal
- Antigen
- P20 of bacterial fusion protein
- Description
- Along with caspase-3 and -6, Caspase-7 is a member of the apoptotic executioner or effector caspases . Caspase-7 is cleaved by granzyme B and caspase-3,-6,-8, and -9. It is suggested that caspase-7 may be an important intrcellular effector of granzyme B-mediated apoptosis and cytotoxic T lymphocytes-induced cell killing in vivo.
- Reactivity
- Human
- Host
- Rat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- Upon receipt, store at 4° C.
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Western blot analysis of untreated Jurkat cells(lane 1) and Jurkat cells treated with 1 µM Etoposide for five hours(lane 2) and anti-Caspase-7 antibody (20F3). GAPDH antibody (poly6314) was used as loading control.
- Conjugate
- Unconjugated