MA5-15159

antibody from Invitrogen Antibodies

Targeting: CASP7 CMH-1, ICE-LAP3, MCH3

Western blot (Data presented on provider website)

Other assay (Supportive data in Antibodypedia)

Antibody Data

Product number

MA5-15159

Provider

Invitrogen Antibodies

Product name

Caspase 7 Monoclonal Antibody (S.606.3)

Antibody type

Monoclonal

Antigen

Recombinant full-length protein

Description

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other caspases.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

S.606.3

Vial size

100 μL

Concentration

140 μg/mL

Storage

-20°C

References

Submitted references

CAMK1D Triggers Immune Resistance of Human Tumor Cells Refractory to Anti-PD-L1 Treatment.

Volpin V, Michels T, Sorrentino A, Menevse AN, Knoll G, Ditz M, Milenkovic VM, Chen CY, Rathinasamy A, Griewank K, Boutros M, Haferkamp S, Berneburg M, Wetzel CH, Seckinger A, Hose D, Goldschmidt H, Ehrenschwender M, Witzens-Harig M, Szoor A, Vereb G, Khandelwal N, Beckhove P
Cancer immunology research 2020 Sep;8(9):1163-1179

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HtrA4 Protease Promotes Chemotherapeutic-Dependent Cancer Cell Death.

Wenta T, Rychlowski M, Jarzab M, Lipinska B
Cells 2019 Sep 20;8(10)

Other assay

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Figure 9 HtrA4 promotes degradation of XIAP and, less efficiently, of beta-tubulin, actin, and pro-caspase 7. The A549 cells with exogenous HtrA4, DeltaN-HtrA4, or their inactive variants (+) induced by adding doxycycline to the medium were treated with 15 uM etoposide for 48 h. Control cells (-) were incubated with etoposide but without doxycycline. The cells and medium were collected and probed with specific antibodies. Representative blots are presented. Densitometric analyses of the immunoblotting results are shown in Figure S5 .