21468-1-AP

antibody from Proteintech Group

Targeting: XRCC1 RCC

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Antibody Data

Product number

21468-1-AP

Provider

Proteintech Group

Product name

XRCC1 antibody

Antibody type

Polyclonal

Description

KD/KO validated XRCC1 antibody (Cat. #21468-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, WB,ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

DNA polymerase beta connects tumorigenicity with the circadian clock in liver cancer through the epigenetic demethylation of Per1.

Chen S, Zhang W, Li X, Cao Z, Liu C
Cell death & disease 2024 Jan 20;15(1):78

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D-type cyclins regulate DNA mismatch repair in the G1 and S phases of the cell cycle, maintaining genome stability.

Rona G, Miwatani-Minter B, Zhang Q, Goldberg HV, Kerzhnerman MA, Howard JB, Simoneschi D, Lane E, Hobbs JW, Sassani E, Wang AA, Keegan S, Laverty DJ, Piett CG, Pongor LS, Xu ML, Andrade J, Thomas A, Sicinski P, Askenazi M, Ueberheide B, Fenyö D, Nagel ZD, Pagano M
bioRxiv : the preprint server for biology 2024 Jan 13;

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CDK-independent role of D-type cyclins in regulating DNA mismatch repair.

Rona G, Miwatani-Minter B, Zhang Q, Goldberg HV, Kerzhnerman MA, Howard JB, Simoneschi D, Lane E, Hobbs JW, Sassani E, Wang AA, Keegan S, Laverty DJ, Piett CG, Pongor LS, Xu ML, Andrade J, Thomas A, Sicinski P, Askenazi M, Ueberheide B, Fenyö D, Nagel ZD, Pagano M
Molecular cell 2024 Apr 4;84(7):1224-1242.e13

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Retrotransposons hijack alt-EJ for DNA replication and eccDNA biogenesis.

Yang F, Su W, Chung OW, Tracy L, Wang L, Ramsden DA, Zhang ZZZ
Nature 2023 Aug;620(7972):218-225

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KDM6B promotes PARthanatos via suppression of O6-methylguanine DNA methyltransferase repair and sustained checkpoint response.

Yang M, Wang C, Zhou M, Bao L, Wang Y, Kumar A, Xing C, Luo W, Wang Y
Nucleic acids research 2022 Jun 24;50(11):6313-6331

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XRCC1 Is a Promising Predictive Biomarker and Facilitates Chemo-Resistance in Gallbladder Cancer.

Wu Z, Miao X, Zhang Y, Li D, Zou Q, Yuan Y, Liu R, Yang Z
Frontiers in molecular biosciences 2020;7:70

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Effects of DNA Damage and Oxidative Stress in Human Bronchial Epithelial Cells Exposed to PM(2.5) from Beijing, China, in Winter.

Niu BY, Li WK, Li JS, Hong QH, Khodahemmati S, Gao JF, Zhou ZX
International journal of environmental research and public health 2020 Jul 6;17(13)

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Berberine attenuates XRCC1-mediated base excision repair and sensitizes breast cancer cells to the chemotherapeutic drugs.

Gao X, Wang J, Li M, Wang J, Lv J, Zhang L, Sun C, Ji J, Yang W, Zhao Z, Mao W
Journal of cellular and molecular medicine 2019 Oct;23(10):6797-6804

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Exosomes Serve as Nanoparticles to Deliver Anti-miR-214 to Reverse Chemoresistance to Cisplatin in Gastric Cancer.

Wang X, Zhang H, Bai M, Ning T, Ge S, Deng T, Liu R, Zhang L, Ying G, Ba Y
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Mar 7;26(3):774-783

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Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis.

Dong H, Shi Q, Song X, Fu J, Hu L, Xu D, Su C, Xia X, Song E, Song Y
Toxicology and applied pharmacology 2015 Jul 1;286(1):10-6