Tissue expression
Cell line expression
XRCC1
gene productRCC
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Featured antibodies
![]() |
![]() |
2 references | Monoclonal |
WB
ICC IP
IHC |
![]() |
![]() |
0 references | Polyclonal |
WB
ICC IHC
|