Tissue expression
Cell line expression
Protein structure
XRCC1
X-ray repair cross complementing 1RCC
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Atlas Antibodies | ![]() |
1 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
7 references | Monoclonal |
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LSBio | ![]() |
Monoclonal |
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antibodies-online | ![]() |
2 references | Polyclonal |
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GeneTex | ![]() |
2 references | Monoclonal |
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