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- Antigen structure
- References [3]
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- Validations
- Immunocytochemistry [3]
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- Product number
- ALX-210-539-R100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-210-539-R100, RRID:AB_2052834
- Product name
- XRCC1 (human) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length protein
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 100 μl
- Storage
- +4°C
Submitted references Radiation-induced mitotic catastrophe in PARG-deficient cells.
XRCC1 is phosphorylated by DNA-dependent protein kinase in response to DNA damage.
XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage.
Amé JC, Fouquerel E, Gauthier LR, Biard D, Boussin FD, Dantzer F, de Murcia G, Schreiber V
Journal of cell science 2009 Jun 15;122(Pt 12):1990-2002
Journal of cell science 2009 Jun 15;122(Pt 12):1990-2002
XRCC1 is phosphorylated by DNA-dependent protein kinase in response to DNA damage.
Lévy N, Martz A, Bresson A, Spenlehauer C, de Murcia G, Ménissier-de Murcia J
Nucleic acids research 2006;34(1):32-41
Nucleic acids research 2006;34(1):32-41
XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage.
Masson M, Niedergang C, Schreiber V, Muller S, Menissier-de Murcia J, de Murcia G
Molecular and cellular biology 1998 Jun;18(6):3563-71
Molecular and cellular biology 1998 Jun;18(6):3563-71
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis of endogenous and recombinant XRCC1 using PAb to XRCC1 (human) (Prod. No. ALX-210-539). Lane 1: HeLa cells. Lane 2: Recombinant human XRCC1 (10ng).
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunocytochemistry of endogenous XRCC1 in HeLa cells using PAb to XRCC1 (human) (Prod. No. ALX-210-539) (1:1'000).
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunoprecipitation of endogenous XRCC1 from HeLa cells. Lane 1: PAb to XRCC1 (human) (Prod. No. ALX-210-304) (5µl). Lane 2: PAb to XRCC1 (human) (Prod. No. ALX-210-304) (10µl). Lane 3: PAb to XRCC1 (human) (Prod. No. ALX-210-539) (5µl). Lane 4: PAb to XRCC1 (human) (Prod. No. ALX-210-539) (10µl). Lane 5: Pre-immune serum.
