Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [3]
- ELISA [1]
- Immunoprecipitation [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN561883 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-MutY Homolog (E. Coli) (MUTYH) (AA 436-535), (partial) antibody
- Antibody type
- Monoclonal
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 436-535, partial
- Isotype
- IgG
- Antibody clone number
- 4D10
- Vial size
- 100 μg
- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Handling
- Aliquot to avoid repeated freezing and thawing.
Submitted references Functional Complementation Assay for 47 MUTYH Variants in a MutY-Disrupted Escherichia coli Strain.
Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer.
Visualization of the physical and functional interaction between hMYH and hRad9 by Dronpa bimolecular fluorescence complementation.
Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells.
Human MutY homolog induces apoptosis in etoposide-treated HEK293 cells.
Effects of base excision repair proteins on mutagenesis by 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) paired with cytosine and adenine.
Immunohistochemistry is not an accurate first step towards the molecular diagnosis of MUTYH-associated polyposis.
Komine K, Shimodaira H, Takao M, Soeda H, Zhang X, Takahashi M, Ishioka C
Human mutation 2015 Jul;36(7):704-11
Human mutation 2015 Jul;36(7):704-11
Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer.
Shinmura K, Goto M, Tao H, Kato H, Suzuki R, Nakamura S, Matsuda T, Yin G, Morita M, Kono S, Sugimura H
Oxidative medicine and cellular longevity 2014;2014:617351
Oxidative medicine and cellular longevity 2014;2014:617351
Visualization of the physical and functional interaction between hMYH and hRad9 by Dronpa bimolecular fluorescence complementation.
Agustina L, Hahm SH, Han SH, Tran AH, Chung JH, Park JH, Park JW, Han YS
BMC molecular biology 2014 Aug 15;15:17
BMC molecular biology 2014 Aug 15;15:17
Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells.
Raetz AG, Xie Y, Kundu S, Brinkmeyer MK, Chang C, David SS
Carcinogenesis 2012 Nov;33(11):2301-9
Carcinogenesis 2012 Nov;33(11):2301-9
Human MutY homolog induces apoptosis in etoposide-treated HEK293 cells.
Hahm SH, Chung JH, Agustina L, Han SH, Yoon IS, Park JH, Kang LW, Park JW, Na JJ, Han YS
Oncology letters 2012 Dec;4(6):1203-1208
Oncology letters 2012 Dec;4(6):1203-1208
Effects of base excision repair proteins on mutagenesis by 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) paired with cytosine and adenine.
Suzuki T, Harashima H, Kamiya H
DNA repair 2010 May 4;9(5):542-50
DNA repair 2010 May 4;9(5):542-50
Immunohistochemistry is not an accurate first step towards the molecular diagnosis of MUTYH-associated polyposis.
van der Post RS, Kets CM, Ligtenberg MJ, van Krieken JH, Hoogerbrugge N
Virchows Archiv : an international journal of pathology 2009 Jan;454(1):25-9
Virchows Archiv : an international journal of pathology 2009 Jan;454(1):25-9
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IP
