MUTYH

gene product
MYH
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
312 antibodies from 37 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Novus Biologicals
8 antibodies
antibodies-online
104 antibodies
Abnova Corporation
6 antibodies
Atlas Antibodies
1 antibody
Biorbyt
14 antibodies
LifeSpan BioSciences, Inc.
36 antibodies
OriGene
10 antibodies
Acris Antibodies GmbH
5 antibodies
Abgent
3 antibodies
Affinity Biosciences
2 antibodies
NovoPro Bioscience Inc.
2 antibodies
Invitrogen Antibodies
6 antibodies
Bioworld Technology, Inc
2 antibodies
Proteintech Group
2 antibodies
Aviva Systems Biology
3 antibodies
St John's Laboratory
5 antibodies
GeneTex
2 antibodies
ProSci
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Antibodies.com
1 antibody
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
MyBioSource
6 antibodies
Arigo
1 antibody
SICGEN
1 antibody
United States Biological
63 antibodies
RabMAbs
3 antibodies
Cell Signaling Technology, Inc
2 antibodies
Creative Biolabs
6 antibodies
RayBiotech, Inc.
2 antibodies
Abiocode, Inc.
1 antibody
Boster Biological Technology
1 antibody
Sigma-Aldrich
3 antibodies
Creative Diagnostics
2 antibodies
Abbiotec
1 antibody
EMD Millipore
1 antibody
GenWay
1 antibody