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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- GTX109632 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX109632, RRID:AB_1952609
- Product name
- XRCC4 antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse
- Host
- Rabbit
Submitted references Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes.
Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation.
Homologous recombination is a primary pathway to repair DNA double-strand breaks generated during DNA rereplication.
An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells.
Chakraborty A, Tapryal N, Venkova T, Horikoshi N, Pandita RK, Sarker AH, Sarkar PS, Pandita TK, Hazra TK
Nature communications 2016 Oct 5;7:13049
Nature communications 2016 Oct 5;7:13049
Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation.
Chakraborty A, Wakamiya M, Venkova-Canova T, Pandita RK, Aguilera-Aguirre L, Sarker AH, Singh DK, Hosoki K, Wood TG, Sharma G, Cardenas V, Sarkar PS, Sur S, Pandita TK, Boldogh I, Hazra TK
The Journal of biological chemistry 2015 Oct 9;290(41):24636-48
The Journal of biological chemistry 2015 Oct 9;290(41):24636-48
Homologous recombination is a primary pathway to repair DNA double-strand breaks generated during DNA rereplication.
Truong LN, Li Y, Sun E, Ang K, Hwang PY, Wu X
The Journal of biological chemistry 2014 Oct 17;289(42):28910-23
The Journal of biological chemistry 2014 Oct 17;289(42):28910-23
An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells.
Sousa MM, Zub KA, Aas PA, Hanssen-Bauer A, Demirovic A, Sarno A, Tian E, Liabakk NB, Slupphaug G
PloS one 2013;8(2):e55493
PloS one 2013;8(2):e55493
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ?g of whole cell lysate) A: Jurkat B: K562 C: HL-60 10% SDS PAGE GTX109632 diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using XRCC4(GTX109632) antibody at 1:200 dilution.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- XRCC4 antibody detects XRCC4 protein at nucleus on HBL435 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded HBL435 xenograft. XRCC4 antibody (GTX109632) dilution: 1:500.
