Tissue expression
Cell line expression
Protein structure
XRCC4
X-ray repair cross complementing 4The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternate transcript variants such as NM_022406 are unlikely to be expressed in some individuals due to a polymorphism (rs1805377) in the last splice acceptor site. [provided by RefSeq, Oct 2019]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
1 references | Polyclonal |
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Proteintech Group | ![]() |
11 references | Polyclonal |
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Atlas Antibodies | ![]() |
4 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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