GTX70293

antibody from GeneTex

Targeting: XRCC4

Western blot (Recommended by provider)

Antibody Data

Product number

GTX70293

Provider

GeneTex

Proper citation

GeneTex Cat#GTX70293, RRID:AB_373301

Product name

XRCC4 antibody

Antibody type

Polyclonal

Antigen

Recombinant protein encoding full-length XRCC4 purified from E. coli.

Description

Mouse polyclonal antiserum to human XRCC4

Reactivity

Human

Host

Mouse

Isotype

IgG

Vial size

50 µl

Concentration

Antiserum

Storage

Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.

References

Submitted references

Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing.

Kusumoto R, Dawut L, Marchetti C, Wan Lee J, Vindigni A, Ramsden D, Bohr VA
Biochemistry 2008 Jul 15;47(28):7548-56

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Up-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks.

Sallmyr A, Tomkinson AE, Rassool FV
Blood 2008 Aug 15;112(4):1413-23

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Radiosensitization of MDA-MB-231 breast tumor cells by adenovirus-mediated overexpression of a fragment of the XRCC4 protein.

Jones KR, Gewirtz DA, Yannone SM, Zhou S, Schatz DG, Valerie K, Povirk LF
Molecular cancer therapeutics 2005 Oct;4(10):1541-7

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Adenovirus-mediated wild-type p53 radiosensitizes human tumor cells by suppressing DNA repair capacity.

Sah NK, Munshi A, Nishikawa T, Mukhopadhyay T, Roth JA, Meyn RE
Molecular cancer therapeutics 2003 Nov;2(11):1223-31