ABIN358036

antibody from antibodies-online

Targeting: FEN1 FEN-1, MF1, RAD2

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN358036

Provider

antibodies-online

Product name

anti-Flap Structure-Specific Endonuclease 1 (FEN1) (Center) antibody

Antibody type

Polyclonal

Antigen

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human FEN1.

Description

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Epitope

Center

Vial size

0.4 mL

Concentration

0.25 mg/mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

The DNA repair endonuclease XPG binds to proliferating cell nuclear antigen (PCNA) and shares sequence elements with the PCNA-binding regions of FEN-1 and cyclin-dependent kinase inhibitor p21.

Gary R, Ludwig DL, Cornelius HL, MacInnes MA, Park MS
The Journal of biological chemistry 1997 Sep 26;272(39):24522-9

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Sequence of human FEN-1, a structure-specific endonuclease, and chromosomal localization of the gene (FEN1) in mouse and human.

Hiraoka LR, Harrington JJ, Gerhard DS, Lieber MR, Hsieh CL
Genomics 1995 Jan 1;25(1):220-5

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Structural and functional homology between mammalian DNase IV and the 5'-nuclease domain of Escherichia coli DNA polymerase I.

Robins P, Pappin DJ, Wood RD, Lindahl T
The Journal of biological chemistry 1994 Nov 18;269(46):28535-8