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- References [15]
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- Product number
- 17032-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17032-1-AP, RRID:AB_2115453
- Product name
- GRK5 antibody
- Antibody type
- Polyclonal
- Description
- GRK5 antibody (Cat. #17032-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references GRK phosphorylation drives β-arrestin-independent internalization of chemokine receptor CXCR5.
A GRK5 centered prognostic framework for bladder cancer based on palmitoylation and epigenetic regulation.
Microcystin-LR Exposure Damages Neurons by Inducing α-Syn Aggregation via MAPK4/GATA2/SNCA and PP2A/GRKs Pathways.
Myocardial delivery of miR30d with peptide-functionalized milk-derived extracellular vesicles for targeted treatment of hypertrophic heart failure.
GRK5 as a Novel Therapeutic Target for Immune Evasion in Testicular Cancer: Insights from Multi-Omics Analysis and Immunotherapeutic Validation.
Free fatty acid receptor-4 regulates T-cell-mediated allogeneic reaction through activating an aryl hydrocarbon receptor pathway.
SNX9 family mediates βarrestin-independent GPCR endocytosis.
GRK5 promoted renal fibrosis via HDAC5/Smad3 signaling pathway.
Identification and validation of chemokine system-related genes in idiopathic pulmonary fibrosis.
METTL3-mediated m6A mRNA methylation regulates neutrophil activation through targeting TLR4 signaling.
Genetic Arg-304-His substitution in GRK5 protects against sepsis progression by alleviating NF-κB-mediated inflammation.
Co-Overexpression of GRK5/ACTC1 Correlates With the Clinical Parameters and Poor Prognosis of Epithelial Ovarian Cancer.
G protein-coupled receptor kinase 5 deletion suppresses synovial inflammation in a murine model of collagen antibody-induced arthritis.
Ligand-dependent internalization of Bombyx mori tachykinin-related peptide receptor is regulated by PKC, GRK5 and β-arrestin2/BmKurtz.
GRK5 Inhibition Attenuates Cartilage Degradation via Decreased NF-κB Signaling.
Crecelius JM, Zhuo Y, Manz AR, Drube J, Schulz S, Hoffmann C, Marchese A
The Journal of biological chemistry 2026 Feb;302(2):111114
The Journal of biological chemistry 2026 Feb;302(2):111114
A GRK5 centered prognostic framework for bladder cancer based on palmitoylation and epigenetic regulation.
Liu J, Zhang Z, Huang B, Fang Y, Lin H
Discover oncology 2025 Sep 26;16(1):1735
Discover oncology 2025 Sep 26;16(1):1735
Microcystin-LR Exposure Damages Neurons by Inducing α-Syn Aggregation via MAPK4/GATA2/SNCA and PP2A/GRKs Pathways.
Yan M, Wu H, Wu T, Wang Y, Su C, Li D, Han X
Molecular neurobiology 2025 May;62(5):6195-6211
Molecular neurobiology 2025 May;62(5):6195-6211
Myocardial delivery of miR30d with peptide-functionalized milk-derived extracellular vesicles for targeted treatment of hypertrophic heart failure.
Tong L, Wang Q, Zhang Y, Lai F, Xu J, Yin W, Zhang S, Wei G, Yin J, Yi H, Storm G, Wang Z, Huang R, Xu T, Wang JW
Biomaterials 2025 May;316:122976
Biomaterials 2025 May;316:122976
GRK5 as a Novel Therapeutic Target for Immune Evasion in Testicular Cancer: Insights from Multi-Omics Analysis and Immunotherapeutic Validation.
Xu C, Zhong Q, Yu N, Zhang X, Yang K, Liu H, Cai M, Zheng Y
Biomedicines 2025 Jul 21;13(7)
Biomedicines 2025 Jul 21;13(7)
Free fatty acid receptor-4 regulates T-cell-mediated allogeneic reaction through activating an aryl hydrocarbon receptor pathway.
Duah M, Zheng F, Shen J, Xu Y, Cao S, Yan Z, Lan Q, Wang Y, Xu K, Pan B
Acta pharmaceutica Sinica. B 2025 Jan;15(1):224-238
Acta pharmaceutica Sinica. B 2025 Jan;15(1):224-238
SNX9 family mediates βarrestin-independent GPCR endocytosis.
Robleto VL, Zhuo Y, Crecelius JM, Benzow S, Marchese A
Communications biology 2024 Nov 7;7(1):1455
Communications biology 2024 Nov 7;7(1):1455
GRK5 promoted renal fibrosis via HDAC5/Smad3 signaling pathway.
Xiang H, Huang J, Song A, Liu F, Xiong J, Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23422
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23422
Identification and validation of chemokine system-related genes in idiopathic pulmonary fibrosis.
Zhao T, Wu X, Zhao X, Yao K, Li X, Ni J
Frontiers in immunology 2023;14:1159856
Frontiers in immunology 2023;14:1159856
METTL3-mediated m6A mRNA methylation regulates neutrophil activation through targeting TLR4 signaling.
Luo S, Liao C, Zhang L, Ling C, Zhang X, Xie P, Su G, Chen Z, Zhang L, Lai T, Tang J
Cell reports 2023 Mar 28;42(3):112259
Cell reports 2023 Mar 28;42(3):112259
Genetic Arg-304-His substitution in GRK5 protects against sepsis progression by alleviating NF-κB-mediated inflammation.
Xu M, Shao Y, Lin K, Liu Y, Lin Y, Lin Y, Yang R, Liu L, Yin M, Liao S, Jiang S, He J
International immunopharmacology 2023 Feb;115:109629
International immunopharmacology 2023 Feb;115:109629
Co-Overexpression of GRK5/ACTC1 Correlates With the Clinical Parameters and Poor Prognosis of Epithelial Ovarian Cancer.
Liu L, Lv J, Lin Z, Ning Y, Li J, Liu P, Chen C
Frontiers in molecular biosciences 2021;8:785922
Frontiers in molecular biosciences 2021;8:785922
G protein-coupled receptor kinase 5 deletion suppresses synovial inflammation in a murine model of collagen antibody-induced arthritis.
Toya M, Akasaki Y, Sueishi T, Kurakazu I, Kuwahara M, Uchida T, Tsutsui T, Tsushima H, Yamada H, Lotz MK, Nakashima Y
Scientific reports 2021 May 18;11(1):10481
Scientific reports 2021 May 18;11(1):10481
Ligand-dependent internalization of Bombyx mori tachykinin-related peptide receptor is regulated by PKC, GRK5 and β-arrestin2/BmKurtz.
He X, Yan L, Wu Q, Zhang G, Zhou N
Biochimica et biophysica acta. Molecular cell research 2020 Jun;1867(6):118690
Biochimica et biophysica acta. Molecular cell research 2020 Jun;1867(6):118690
GRK5 Inhibition Attenuates Cartilage Degradation via Decreased NF-κB Signaling.
Sueishi T, Akasaki Y, Goto N, Kurakazu I, Toya M, Kuwahara M, Uchida T, Hayashida M, Tsushima H, Bekki H, Lotz MK, Nakashima Y
Arthritis & rheumatology (Hoboken, N.J.) 2020 Apr;72(4):620-631
Arthritis & rheumatology (Hoboken, N.J.) 2020 Apr;72(4):620-631
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GRK5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GRK5. This antibody recognizes human, mouse, rat antigen. The GRK5 antibody has been validated for the following applications: ELISA, WB analysis.
