Antibody data
- Antibody Data
- Antigen structure
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- Product number
- 381 - Provider product page
- Provider
- YO Proteins AB
- Proper citation
- YO Proteins Cat#381, RRID:AB_2252479
- Product name
- Mouse anti-human urokinase monoclonal antibody, clone PGM2001
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody (clone PGM2001, IgG1 fraction) anti-human urokinase. Binds to human high molecular weight single-chain urokinase type plasminogen activator (HMW-scuPA, 54 kDa), to high molecular weight two-chain urokinase type plasminogen activator (HMW-tcuPA, 52 kDa) and to low molecular weight single-chain urokinase type plasminogen activator (LMW-scuPA, 33kDa) with high affinity (Kd = 0.1 nM) and does inhibit the ability of urokinase to activate plasminogen. Urokinase reaction with synthetic substrate S2444 is not inhibited. Highly specific for urokinase, no cross-reactions were found with other serine proteases (tissue plasminogen activator, plasmin, trypsin, chymotrypsin, elastase, and thrombin). Human plasma or plasma proteins do not interfere with its binding to urokinase
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 1 ml
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