AGTO-L071L

antibody from Creative Biolabs

Targeting: PLAU UPA, URK

No application information provided.

Antibody Data

Product number

AGTO-L071L

Provider

Creative Biolabs

Product name

uPAcs-Luffin-¦Â immunotoxin

Antibody type

Monoclonal

Description

This immunotoxin was achieved by conjugating/fusing the uPAcs to loofah toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to lung cancer cells and the toxin enters cells by receptor-mediated endocytosis. Then loofah toxin inhibits protein synthesis by damaging the 60S subunit of mammalian ribosomes. It was designed for treatment of lung cancer.

Reactivity

Human

Host

Human