Tissue expression
Cell line expression

TIRAP

gene product
Mal, wyatt 
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
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531 antibodies from 39 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
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Antibodies.com
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MilliporeSigma / Merck KGaA
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Affinity Biosciences
1 antibody
Cell Signaling Technology, Inc
1 antibody
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Aviva Systems Biology
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MyBioSource
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RabMAbs
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Abbexa
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Creative Biolabs
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eBioscience, An Affymetrix Company
2 antibodies
GenWay
1 antibody
Rockland Immunochemicals, Inc.
1 antibody