TIRAP

gene product
Mal, wyatt
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
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492 antibodies from 36 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
8 antibodies
Abnova Corporation
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OriGene
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antibodies-online
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Novus Biologicals
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Enzo Life Sciences
2 antibodies
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NovoPro Bioscience Inc.
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ProSci
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St John's Laboratory
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Arigo
3 antibodies
Atlas Antibodies
1 antibody
Bioworld Technology, Inc
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
Antibodies.com
2 antibodies
Sigma-Aldrich
5 antibodies
Affinity Biosciences
1 antibody
Cell Signaling Technology, Inc
1 antibody
Everest Biotech
2 antibodies
NSJ Bioreagents
2 antibodies
Abbkine Scientific Co.Ltd.
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Aviva Systems Biology
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Creative Biolabs
13 antibodies
MyBioSource
6 antibodies
RabMAbs
4 antibodies
RayBiotech, Inc.
3 antibodies
Boster Biological Technology
1 antibody
United States Biological
51 antibodies
Creative Diagnostics
3 antibodies
eBioscience, An Affymetrix Company
2 antibodies
GenWay
1 antibody