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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [7]
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- Product number
- ABIN401056 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide corresponding to a region near the carboxy terminus of mouse TIRAPprotein
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml (by UV absorbance at 280 nm)
- Storage
- Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Submitted references The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction.
Toll-like receptors.
The Toll-IL-1 receptor adaptor family grows to five members.
TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression.
Innate immune recognition.
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors.
Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.
McGettrick AF, O'Neill LA
Molecular immunology 2004 Jul;41(6-7):577-82
Molecular immunology 2004 Jul;41(6-7):577-82
Toll-like receptors.
Takeda K, Kaisho T, Akira S
Annual review of immunology 2003;21:335-76
Annual review of immunology 2003;21:335-76
The Toll-IL-1 receptor adaptor family grows to five members.
O'Neill LA, Fitzgerald KA, Bowie AG
Trends in immunology 2003 Jun;24(6):286-90
Trends in immunology 2003 Jun;24(6):286-90
TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression.
Vogel SN, Fitzgerald KA, Fenton MJ
Molecular interventions 2003 Dec;3(8):466-77
Molecular interventions 2003 Dec;3(8):466-77
Innate immune recognition.
Janeway CA Jr, Medzhitov R
Annual review of immunology 2002;20:197-216
Annual review of immunology 2002;20:197-216
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors.
Horng T, Barton GM, Flavell RA, Medzhitov R
Nature 2002 Nov 21;420(6913):329-33
Nature 2002 Nov 21;420(6913):329-33
Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.
Yamamoto M, Sato S, Hemmi H, Sanjo H, Uematsu S, Kaisho T, Hoshino K, Takeuchi O, Kobayashi M, Fujita T, Takeda K, Akira S
Nature 2002 Nov 21;420(6913):324-9
Nature 2002 Nov 21;420(6913):324-9
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