13989-1-AP

antibody from Proteintech Group

Targeting: ACSL1 ACS1, FACL1, FACL2, LACS, LACS1, LACS2

Provider product page for 13989-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [83]
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Validations
Western blot [1]

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Product number: 13989-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#13989-1-AP, RRID:AB_2257870
Product name: ACSL1 antibody
Antibody type: Polyclonal
Description: KD/KO validated ACSL1 antibody (Cat. #13989-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

ACSL1 protein structure - 13989-1-AP shown in red.

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Oxidative medicine and cellular longevity 2020;2020:5849794

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Cell chemical biology 2019 Mar 21;26(3):420-432.e9

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Zhou L, Wang Z, Hu C, Zhang C, Kovatcheva-Datchary P, Yu D, Liu S, Ren F, Wang X, Li Y, Hou X, Piao H, Lu X, Zhang Y, Xu G
Journal of proteome research 2019 Mar 1;18(3):960-969

Fe(3)O(4)@OA@Poloxamer nanoparticles lower triglyceride in hepatocytes through liposuction effect and nano-enzyme effect.

Sun Y, Shi F, Niu Y, Zhang Y, Xiong F
Colloids and surfaces. B, Biointerfaces 2019 Dec 1;184:110528

Mesenchymal glioblastoma constitutes a major ceRNA signature in the TGF-β pathway.

Wang Q, Cai J, Fang C, Yang C, Zhou J, Tan Y, Wang Y, Li Y, Meng X, Zhao K, Yi K, Zhang S, Zhang J, Jiang C, Zhang J, Kang C
Theranostics 2018;8(17):4733-4749

Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomics for the investigation of the effect of Hugan Qingzhi on non-alcoholic fatty liver disease in rats.

Yao X, Xia F, Tang W, Xiao C, Yang M, Zhou B
Journal of ethnopharmacology 2018 Feb 15;212:208-215

PPARγ maintains the metabolic heterogeneity and homeostasis of renal tubules.

Lyu Z, Mao Z, Li Q, Xia Y, Liu Y, He Q, Wang Y, Zhao H, Lu Z, Zhou Q
EBioMedicine 2018 Dec;38:178-190

Aspirin suppresses the abnormal lipid metabolism in liver cancer cells via disrupting an NFκB-ACSL1 signaling.

Yang G, Wang Y, Feng J, Liu Y, Wang T, Zhao M, Ye L, Zhang X
Biochemical and biophysical research communications 2017 May 6;486(3):827-832

HBXIP up-regulates ACSL1 through activating transcriptional factor Sp1 in breast cancer.

Wang Y, Cai X, Zhang S, Cui M, Liu F, Sun B, Zhang W, Zhang X, Ye L
Biochemical and biophysical research communications 2017 Mar 11;484(3):565-571

Protective effects of glycyrrhizic acid from edible botanical glycyrrhiza glabra against non-alcoholic steatohepatitis in mice.

Wang C, Duan X, Sun X, Liu Z, Sun P, Yang X, Sun H, Liu K, Meng Q
Food & function 2016 Sep 14;7(9):3716-23

Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients.

Wang MD, Wu H, Fu GB, Zhang HL, Zhou X, Tang L, Dong LW, Qin CJ, Huang S, Zhao LH, Zeng M, Wu MC, Yan HX, Wang HY
Hepatology (Baltimore, Md.) 2016 Apr;63(4):1272-86

Long noncoding RNA HULC modulates abnormal lipid metabolism in hepatoma cells through an miR-9-mediated RXRA signaling pathway.

Cui M, Xiao Z, Wang Y, Zheng M, Song T, Cai X, Sun B, Ye L, Zhang X
Cancer research 2015 Mar 1;75(5):846-57

Potent effects of dioscin against obesity in mice.

Liu M, Xu L, Yin L, Qi Y, Xu Y, Han X, Zhao Y, Sun H, Yao J, Lin Y, Liu K, Peng J
Scientific reports 2015 Jan 22;5:7973

HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.

Huang D, Li T, Li X, Zhang L, Sun L, He X, Zhong X, Jia D, Song L, Semenza GL, Gao P, Zhang H
Cell reports 2014 Sep 25;8(6):1930-1942

Protective effects of dioscin against alcohol-induced liver injury.

Xu T, Zheng L, Xu L, Yin L, Qi Y, Xu Y, Han X, Peng J
Archives of toxicology 2014 Mar;88(3):739-53

MiR-205 modulates abnormal lipid metabolism of hepatoma cells via targeting acyl-CoA synthetase long-chain family member 1 (ACSL1) mRNA.

Cui M, Wang Y, Sun B, Xiao Z, Ye L, Zhang X
Biochemical and biophysical research communications 2014 Feb 7;444(2):270-5

Chinese medicine formula lingguizhugan decoction improves Beta-oxidation and metabolism of Fatty Acid in high-fat-diet-induced rat model of Fatty liver disease.

Liu T, Yang LL, Zou L, Li DF, Wen HZ, Zheng PY, Xing LJ, Song HY, Tang XD, Ji G
Evidence-based complementary and alternative medicine : eCAM 2013;2013:429738

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The ACSL1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ACSL1. This antibody recognizes human,mouse,rat antigen. The ACSL1 antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 13989-1-AP.pdf

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