ACSL1

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Description

acyl-CoA synthetase long-chain family member 1

Protein family

Enzymes, Mapped to UniProt SWISS-PROT, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

4:q35.1 (184755595 - 184826818)

Ensembl ID

ENSG00000151726  (ver. 84.38)

Orthologs

Mouse Acsl1: ENSMUSG00000018796

UniProt

P33121

neXtProt

NX_P33121

Human splice variants
Mouse splice variants