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- Antibody Data
- Antigen structure
- References [23]
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- Product number
- 25142-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- HNRNPA3 antibody
- Antibody type
- Polyclonal
- Description
- HNRNPA3 antibody (Cat. #25142-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ENDOU-1-induced cytoplasmic HnRNPA3 recognizes m6A methylation on the upstream reading frame of human CHOP transcripts to achieve maximal CHOP translation.
A conserved mammalian mecciRNA, mecciATP6, regulates mitochondrial homeostasis through interaction with HNRNPA3.
Mannose Inhibits NSCLC Growth and Inflammatory Microenvironment by Regulating Gut Microbiota and Targeting OGT/hnRNP R/JUN/IL-8 Axis.
Sustained cancer-relevant alternative RNA splicing events driven by PRMT5 in high-risk neuroblastoma.
Characterization and functional analysis of chicken hnRNP protein.
Altered mRNA transport and local translation in i3Neurons with RNA-binding protein knockdown.
Maintenance of p-eIF2α levels by the eIF2B complex is vital for colorectal cancer.
GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy.
Loss-of-function variant in TDRD6 cause male infertility with severe oligo-astheno-teratozoospermia in human and mice.
Altered mRNA transport and local translation in iNeurons with RNA binding protein knockdown.
RNA damage compartmentalization by DHX9 stress granules.
PEDV inhibits HNRNPA3 expression by miR-218-5p to enhance cellular lipid accumulation and promote viral replication.
Heterogeneous nuclear ribonucleoprotein A3 binds to the internal ribosomal entry site of enterovirus A71 and affects virus replication in neural cells.
SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia.
Circ_0114581 promotes osteogenic differentiation of BMSCs via the MiR-155-5p/HNRNPA3 axis.
ALS-linked cytoplasmic FUS assemblies are compositionally different from physiological stress granules and sequester hnRNPA3, a novel modifier of FUS toxicity.
Abnormal expression of HNRNPA3 in multistep hepatocarcinogenesis.
Identification of mecciRNAs and their roles in the mitochondrial entry of proteins.
A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism.
RNA Binding Motif Protein RBM45 Regulates Expression of the 11-Kilodalton Protein of Parvovirus B19 through Binding to Novel Intron Splicing Enhancers.
Novel Long Noncoding RNA, Macrophage Inflammation-Suppressing Transcript (MIST), Regulates Macrophage Activation During Obesity.
Integrated Functional Analysis of the Nuclear Proteome of Classically and Alternatively Activated Macrophages.
Stress granules regulate stress-induced paraspeckle assembly.
Lee HC, Huang YH, Hsieh CC, Ke YN, Tsai HJ
Cellular and molecular life sciences : CMLS 2026 Mar 28;83(1)
Cellular and molecular life sciences : CMLS 2026 Mar 28;83(1)
A conserved mammalian mecciRNA, mecciATP6, regulates mitochondrial homeostasis through interaction with HNRNPA3.
Cao X, Sui J, Shan G, Liu X
Non-coding RNA research 2026 Aug;19:28-39
Non-coding RNA research 2026 Aug;19:28-39
Mannose Inhibits NSCLC Growth and Inflammatory Microenvironment by Regulating Gut Microbiota and Targeting OGT/hnRNP R/JUN/IL-8 Axis.
Jin H, He H, Li J, Liu X, Cai Q, Shi J, Hao Z, He J
International journal of biological sciences 2025;21(4):1566-1584
International journal of biological sciences 2025;21(4):1566-1584
Sustained cancer-relevant alternative RNA splicing events driven by PRMT5 in high-risk neuroblastoma.
Bate-Eya LT, Albayrak G, Carr SM, Shrestha A, Kanapin A, Samsonova A, La Thangue NB
Molecular oncology 2025 Mar;19(3):741-763
Molecular oncology 2025 Mar;19(3):741-763
Characterization and functional analysis of chicken hnRNP protein.
Wang K, Huang M, Zeng Q, Wu H
Poultry science 2025 Mar;104(3):104859
Poultry science 2025 Mar;104(3):104859
Altered mRNA transport and local translation in i3Neurons with RNA-binding protein knockdown.
Dargan R, Mikheenko A, Johnson NL, Packer BE, Li Z, Craig EJ, Como CN, Sarbanes SL, Bereda C, Hao Y, Mehta PR, Keuss M, Nalls MA, Qi YA, Weller CA, Fratta P, Ryan VH
Nucleic acids research 2025 Jul 19;53(14)
Nucleic acids research 2025 Jul 19;53(14)
Maintenance of p-eIF2α levels by the eIF2B complex is vital for colorectal cancer.
Škapik IP, Giacomelli C, Hahn S, Deinlein H, Gallant P, Diebold M, Biayna J, Hendricks A, Olimski L, Otto C, Kastner C, Wolf E, Schülein-Völk C, Maurus K, Rosenwald A, Schleussner N, Jackstadt RF, Schlegel N, Germer CT, Bushell M, Eilers M, Schmidt S, Wiegering A
The EMBO journal 2025 Apr;44(7):2075-2105
The EMBO journal 2025 Apr;44(7):2075-2105
GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy.
Du L, Liu S, Lu Y, Ren D, Yu X, Hu Y, Yang T, Yang Q, Ming J, Zhang J, Yin X, Lu Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2407462
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2407462
Loss-of-function variant in TDRD6 cause male infertility with severe oligo-astheno-teratozoospermia in human and mice.
Bi X, Jin H, Wan F, Xia Y, Guo H, Chen S, Wang B
Journal of cellular and molecular medicine 2024 Sep;28(18):e18580
Journal of cellular and molecular medicine 2024 Sep;28(18):e18580
Altered mRNA transport and local translation in iNeurons with RNA binding protein knockdown.
Dargan R, Mikheenko A, Johnson NL, Packer B, Li Z, Craig EJ, Sarbanes SL, Bereda C, Mehta PR, Keuss M, Nalls MA, Qi YA, Weller CA, Fratta P, Ryan VH
bioRxiv : the preprint server for biology 2024 Sep 27;
bioRxiv : the preprint server for biology 2024 Sep 27;
RNA damage compartmentalization by DHX9 stress granules.
Zhou Y, Panhale A, Shvedunova M, Balan M, Gomez-Auli A, Holz H, Seyfferth J, Helmstädter M, Kayser S, Zhao Y, Erdogdu NU, Grzadzielewska I, Mittler G, Manke T, Akhtar A
Cell 2024 Mar 28;187(7):1701-1718.e28
Cell 2024 Mar 28;187(7):1701-1718.e28
PEDV inhibits HNRNPA3 expression by miR-218-5p to enhance cellular lipid accumulation and promote viral replication.
Shi X, Zhang Q, Yang N, Wang Q, Zhang Y, Xu X
mBio 2024 Feb 14;15(2):e0319723
mBio 2024 Feb 14;15(2):e0319723
Heterogeneous nuclear ribonucleoprotein A3 binds to the internal ribosomal entry site of enterovirus A71 and affects virus replication in neural cells.
Lin JY, Lin JY, Kuo RL, Huang HI
Journal of cellular biochemistry 2024 Dec;125(12):e30575
Journal of cellular biochemistry 2024 Dec;125(12):e30575
SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia.
Luo YW, Zhou JP, Ji H, Xu D, Zheng A, Wang X, Dai Z, Luo Z, Cao F, Wang XY, Bai Y, Chen D, Chen Y, Wang Q, Yang Y, Zhang X, Chiu S, Peng X, Huang AL, Tang KF
Nature communications 2024 Aug 13;15(1):6964
Nature communications 2024 Aug 13;15(1):6964
Circ_0114581 promotes osteogenic differentiation of BMSCs via the MiR-155-5p/HNRNPA3 axis.
Li H, Wang C, Yao J, Jin Y, Song X, Meng Q, Wu J, Liu Q, Liu M, Sun H
Life sciences 2023 Nov 15;333:122127
Life sciences 2023 Nov 15;333:122127
ALS-linked cytoplasmic FUS assemblies are compositionally different from physiological stress granules and sequester hnRNPA3, a novel modifier of FUS toxicity.
An H, Litscher G, Watanabe N, Wei W, Hashimoto T, Iwatsubo T, Buchman VL, Shelkovnikova TA
Neurobiology of disease 2022 Jan;162:105585
Neurobiology of disease 2022 Jan;162:105585
Abnormal expression of HNRNPA3 in multistep hepatocarcinogenesis.
Ren X, Dong Y, Duan M, Zhang H, Gao P
Oncology letters 2021 Jan;21(1):46
Oncology letters 2021 Jan;21(1):46
Identification of mecciRNAs and their roles in the mitochondrial entry of proteins.
Liu X, Wang X, Li J, Hu S, Deng Y, Yin H, Bao X, Zhang QC, Wang G, Wang B, Shi Q, Shan G
Science China. Life sciences 2020 Oct;63(10):1429-1449
Science China. Life sciences 2020 Oct;63(10):1429-1449
A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism.
Ho JJD, Balukoff NC, Theodoridis PR, Wang M, Krieger JR, Schatz JH, Lee S
Nature communications 2020 May 29;11(1):2677
Nature communications 2020 May 29;11(1):2677
RNA Binding Motif Protein RBM45 Regulates Expression of the 11-Kilodalton Protein of Parvovirus B19 through Binding to Novel Intron Splicing Enhancers.
Wang J, Ganaie SS, Cheng F, Xu P, Ning K, Wang X, Kleiboeker S, Cheng S, Qiu J
mBio 2020 Mar 10;11(2)
mBio 2020 Mar 10;11(2)
Novel Long Noncoding RNA, Macrophage Inflammation-Suppressing Transcript (MIST), Regulates Macrophage Activation During Obesity.
Stapleton K, Das S, Reddy MA, Leung A, Amaram V, Lanting L, Chen Z, Zhang L, Palanivel R, Deiuliis JA, Natarajan R
Arteriosclerosis, thrombosis, and vascular biology 2020 Apr;40(4):914-928
Arteriosclerosis, thrombosis, and vascular biology 2020 Apr;40(4):914-928
Integrated Functional Analysis of the Nuclear Proteome of Classically and Alternatively Activated Macrophages.
Wiktorowicz JE, Chowdhury IH, Stafford S, Choudhuri S, Dey N, Garg NJ
Mediators of inflammation 2019;2019:3481430
Mediators of inflammation 2019;2019:3481430
Stress granules regulate stress-induced paraspeckle assembly.
An H, Tan JT, Shelkovnikova TA
The Journal of cell biology 2019 Dec 2;218(12):4127-4140
The Journal of cell biology 2019 Dec 2;218(12):4127-4140
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 25142-1-AP( HNRNPA3 Antibody) at dilution of 1:1000
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HNRNPA3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human HNRNPA3. This antibody recognizes human, mouse antigen. The HNRNPA3 antibody has been validated for the following applications: ELISA, WB analysis.
