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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [7]
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- Product number
- ABIN499112 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Sphingosine Kinase 1 (SPHK1) (AA 150-200) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide corresponding to unique epitope on Sphk1 selected from Mid-Region, amino acids 150-200. .Remarks: The SPHK1 peptide was post-synthetically covalently modified to achieve desired antigenicity
- Description
- Immobilized-Antigen Affinity Chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- AA 150-200
- Vial size
- 0.1 mg
- Concentration
- 0.64-0.72 mg/mL
- Storage
- Store the antibody undiluted (in aliquots) at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references SphK1 regulates proinflammatory responses associated with endotoxin and polymicrobial sepsis.
CXCL4-induced monocyte survival, cytokine expression, and oxygen radical formation is regulated by sphingosine kinase 1.
Sphingosine kinase-1 is central to androgen-regulated prostate cancer growth and survival.
Sphingosine kinase 1 inhibition sensitizes hormone-resistant prostate cancer to docetaxel.
Sphingosine-1-phosphate: an enigmatic signalling lipid.
An oncogenic role of sphingosine kinase.
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate.
Puneet P, Yap CT, Wong L, Lam Y, Koh DR, Moochhala S, Pfeilschifter J, Huwiler A, Melendez AJ
Science (New York, N.Y.) 2010 Jun 4;328(5983):1290-4
Science (New York, N.Y.) 2010 Jun 4;328(5983):1290-4
CXCL4-induced monocyte survival, cytokine expression, and oxygen radical formation is regulated by sphingosine kinase 1.
Kasper B, Winoto-Morbach S, Mittelstädt J, Brandt E, Schütze S, Petersen F
European journal of immunology 2010 Apr;40(4):1162-73
European journal of immunology 2010 Apr;40(4):1162-73
Sphingosine kinase-1 is central to androgen-regulated prostate cancer growth and survival.
Dayon A, Brizuela L, Martin C, Mazerolles C, Pirot N, Doumerc N, Nogueira L, Golzio M, Teissié J, Serre G, Rischmann P, Malavaud B, Cuvillier O
PloS one 2009 Nov 26;4(11):e8048
PloS one 2009 Nov 26;4(11):e8048
Sphingosine kinase 1 inhibition sensitizes hormone-resistant prostate cancer to docetaxel.
Sauer L, Nunes J, Salunkhe V, Skalska L, Kohama T, Cuvillier O, Waxman J, Pchejetski D
International journal of cancer. Journal international du cancer 2009 Dec 1;125(11):2728-36
International journal of cancer. Journal international du cancer 2009 Dec 1;125(11):2728-36
Sphingosine-1-phosphate: an enigmatic signalling lipid.
Spiegel S, Milstien S
Nature reviews. Molecular cell biology 2003 May;4(5):397-407
Nature reviews. Molecular cell biology 2003 May;4(5):397-407
An oncogenic role of sphingosine kinase.
Xia P, Gamble JR, Wang L, Pitson SM, Moretti PA, Wattenberg BW, D'Andrea RJ, Vadas MA
Current biology : CB 2000 Nov 30;10(23):1527-30
Current biology : CB 2000 Nov 30;10(23):1527-30
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate.
Cuvillier O, Pirianov G, Kleuser B, Vanek PG, Coso OA, Gutkind S, Spiegel S
Nature 1996 Jun 27;381(6585):800-3
Nature 1996 Jun 27;381(6585):800-3
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