SPHK1

gene product
SPHK
The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
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669 antibodies from 43 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
36 antibodies
R&D Systems
3 antibodies
antibodies-online
227 antibodies
Abgent
10 antibodies
GeneTex
8 antibodies
Abnova Corporation
16 antibodies
Biorbyt
26 antibodies
Aviva Systems Biology
8 antibodies
LifeSpan BioSciences, Inc.
101 antibodies
NSJ Bioreagents
6 antibodies
OriGene
17 antibodies
Boster Biological Technology
2 antibodies
Invitrogen Antibodies
14 antibodies
Bioworld Technology, Inc
1 antibody
NovoPro Bioscience Inc.
10 antibodies
ProSci
6 antibodies
Affinity Biosciences
2 antibodies
Antibodies.com
1 antibody
Arigo
4 antibodies
Acris Antibodies GmbH
21 antibodies
Proteintech Group
2 antibodies
Atlas Antibodies
2 antibodies
St John's Laboratory
4 antibodies
Everest Biotech
2 antibodies
FabGennix
3 antibodies
Bethyl Laboratories
2 antibodies
Cell Signaling Technology, Inc
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
RabMAbs
5 antibodies
BioLegend
1 antibody
United States Biological
74 antibodies
MyBioSource
14 antibodies
Creative Biolabs
7 antibodies
Abiocode, Inc.
1 antibody
Sigma-Aldrich
7 antibodies
Abbiotec
1 antibody
EMD Millipore
1 antibody
Exalpha Biologicals, Inc.
1 antibody
Abbexa
3 antibodies
RayBiotech, Inc.
3 antibodies
Creative Diagnostics
1 antibody
GenWay
1 antibody