TAAR1

The protein encoded by this gene is a G-protein coupled receptor activated by trace amines. The encoded protein responds little or not at all to dopamine, serotonin, epinephrine, or histamine, but responds well to beta-phenylethylamine, p-tyramine, octopamine, and tryptamine. While primarily functioning in neurologic systems, there is evidence that this gene is involved in blood cell and immunologic functions as well. This gene is thought to be intronless. [provided by RefSeq, Nov 2015]

Description

Trace amine associated receptor 1

Tissue specificity

Tissue enriched (stomach)

Predicted location

Membrane

Protein family

FDA approved drug targets
G-protein coupled receptors
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins

Chromosome

6 (132644898 - 132646051)

Ensembl ID

ENSG00000146399  (ver. 103.38)

Orthologs

Mouse Taar1: ENSMUSG00000056379

UniProt

Q96RJ0

neXtProt

NX_Q96RJ0

Human splice variants
Mouse splice variants

Protein structure