Tissue expression
Cell line expression
Protein structure
BAIAP2
BAR/IMD domain containing adaptor protein 2BAP2, IRSp53, WAML
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2009]
Top validated antibodies |
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Proteintech Group | ![]() |
8 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Monoclonal |
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OriGene | ![]() |
Monoclonal |
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antibodies-online | ![]() |
Monoclonal |
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