ABIN1673609

antibody from antibodies-online

Targeting: COL1A1 OI4

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1673609

Provider

antibodies-online

Product name

anti-Collagen, Type I, alpha 1 (COL1A1) (C-Term) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence at the C-terminal of human COL1A1, different from the related rat and mouse sequences by two amino acids.Immunogen affinity purified.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

100 μg

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Mutations near amino end of alpha1(I) collagen cause combined osteogenesis imperfecta/Ehlers-Danlos syndrome by interference with N-propeptide processing.

Cabral WA, Makareeva E, Colige A, Letocha AD, Ty JM, Yeowell HN, Pals G, Leikin S, Marini JC
The Journal of biological chemistry 2005 May 13;280(19):19259-69

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Ocular hypertension in mice with a targeted type I collagen mutation.

Aihara M, Lindsey JD, Weinreb RN
Investigative ophthalmology & visual science 2003 Apr;44(4):1581-5