COL1A1

gene product
OI4
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
545 antibodies from 36 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
76 antibodies
GeneTex
14 antibodies
Boster Biological Technology
5 antibodies
Invitrogen Antibodies
14 antibodies
Acris Antibodies GmbH
39 antibodies
Rockland Immunochemicals, Inc.
8 antibodies
Abnova Corporation
11 antibodies
NSJ Bioreagents
5 antibodies
LifeSpan BioSciences, Inc.
75 antibodies
OriGene
30 antibodies
R&D Systems
2 antibodies
Biorbyt
54 antibodies
NovoPro Bioscience Inc.
3 antibodies
Aviva Systems Biology
22 antibodies
Arigo
2 antibodies
antibodies-online
30 antibodies
Abgent
4 antibodies
Abbiotec
7 antibodies
St John's Laboratory
10 antibodies
YO Proteins AB
7 antibodies
PhosphoSolutions
2 antibodies
Cell Signaling Technology, Inc
1 antibody
ProSci
6 antibodies
Creative Diagnostics
11 antibodies
GenWay
27 antibodies
EMD Millipore
14 antibodies
Atlas Antibodies
2 antibodies
Creative Biolabs
5 antibodies
Bioworld Technology, Inc
1 antibody
MyBioSource
16 antibodies
Abbkine Scientific Co.Ltd.
6 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
20 antibodies
Sigma-Aldrich
2 antibodies
RabMAbs
1 antibody