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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [385]
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- Product number
- 67288-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- Collagen Type I antibody
- Antibody type
- Monoclonal
- Description
- Collagen Type I antibody (Cat. #67288-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, pig and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1E9A7
- Vial size
- 20ul, 150ul
Submitted references Huanggan decoction ameliorates cholestatic hepatic fibrosis in rats via TGF-β1/Smad3 signaling pathway.
Bladder cancer-induced CVD mortality: Role of CAPG protein.
Oxidative modification of skin collagen.
AURKA Activates FOXO3a to Form a Positive Feedback Loop in the Proliferation and Migration of Keloid Fibroblasts.
Ascorbic Acid Modulates Collagen Properties in Glucocorticoid-Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation.
JOSD2 alleviates hypertensive renal disease through deubiquitinating AKT in renal tubular epithelial cells.
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
The m(5)C demethylase TET1 is identified as a key regulator of scleral remodeling in myopia.
WDR63 enhances the chondrogenic differentiation and regenerative potential of stem cell from apical papilla by facilitating vimentin function to promote mitochondrial fission.
Evaluation of a 3,5-diethoxycarbonyl-1,4-dihydrocollidine diet-induced mouse model in a comparative experimental study of portal hypertension.
The CDO1-ACSM3 Axis Mediates Renal Tubule Lipid Deposition and Injury by Causing Mitochondrial Dysfunction in Lupus Nephritis.
Glutamine-dependent changes in fibroblast-derived extracellular matrix dictate cancer cell behavior.
GDF15-Treated iPSC-MSC-Derived Exosomes Alleviate Fibrosis Post-Myocardial Infarction via Repression of the MFAP4/ERK/Drp1 Axis.
Multi-omics and AI-guided discovery and validation of sisomicin as a COPA-targeting agent for pathological scar inhibition.
Class Effect of SGLT2 Inhibitors Against Doxorubicin-Induced Cardiotoxicity via Regulating Adenosine Kinase Mediated-Cardiac Oxidative Stress.
Kaempferide alleviates glucocorticoid-induced osteoporosis by targeting ferroptosis through the GSK3β/Nrf-2/GPX4 pathway.
DNA tetrahedron-mediated vascular targeted delivery of astragaloside IV enhances distraction osteogenesis via PI3K/AKT/FOXO pathway.
Deficiency of Med1 in keratinocytes augments dermal fibrosis and inflammation in scleroderma.
Asymmetrical paravertebral muscles fibrosis causes progression of adolescent idiopathic scoliosis via myostatin signalling in fibro-adipogenic progenitors.
High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE(‑/‑) mice via the NAD(+)‑mediated SIRT1/MFN2 pathway.
Biomimetic nanoplatforms for combined DDR2 inhibition and photothermal therapy in dense breast cancer treatment.
CSB6B attenuates renal inflammation and fibrosis by inhibiting the activation of NLRP3 inflammasome through the NLRP3/Caspase-1/GSDMD/IL-1β signaling pathway.
Yujie recipe attenuates bleomycin-induced pulmonary fibrosis via suppressing NF-κB/NLRP3 signaling in a Nrf2-dependent manner.
Spil-mediated sEH overexpression contributes to the senescence of alveolar epithelial cells during pulmonary fibrosis in mice.
Isolation of Chicken Intestinal Glial Cells and Their Transcriptomic Response to LPS.
Microneedle-delivered ROS-adaptive asiatic acid nanoparticles promote scarless repair via remodeling the pathological microenvironment.
Mechanism of Curcumin in the Treatment of Intrauterine Adhesions Based on Network Pharmacology, Molecular docking, and Experimental Validation.
Synergistic neuroprotective effects of the ROCK inhibitor Y27632 and atorvastatin in optineurin-E50K-mutant mice through inhibition of scleral fibroblast transdifferentiation.
Rabeprazole attenuates fibrosis by modulating SMAD3 linker region phosphorylation.
Oxidative Fragmentation of Collagen in Skin: Relevance to Skin Aging and Skin Diseases.
A Biomimetic Norepinephrine-Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical-Sized Bone Defects.
Integrated network toxicology and multi-omics analysis reveals the role of tobacco-specific carcinogen NNK in idiopathic pulmonary fibrosis pathogenesis.
A pan-cancer single-cell transcriptomic atlas of human bone metastases.
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
EP300 attenuates ferroptosis and stimulates proliferation, migration, and fibrosis of keloid fibroblasts via YY1/GPX4 axis.
Phosphoglucose isomerase directs the inflammatory response, calcium influx and fibroblast migration in keloids.
A translational systems medicine approach to devising nanotherapeutics for targeted intervention of MASLD.
Bioinspired scaffold recapitulating chondrogenic ontogeny and microenvironment for functional cartilage regeneration.
Upregulation of PLOD2 expression promotes the development of psoriasis: A connection between keratinocytes and fibroblasts.
Novel transcription factor zinc finger 514 suppresses lung adenocarcinoma progression and enhances cisplatin sensitivity via transcriptional repression of COL1A1.
Wnt/OPG signaling axis drives ectopic mandibular regeneration: Mechanism mediated by tibial periosteal stem cell sheets.
Vitamin D attenuates the progression of pulmonary fibrosis via inhibiting thymidine kinase 1/PFKFB3-driven glycolysis.
Citicoline Restores Endoplasmic Reticulum Homeostasis by Regulating Oxidative Stress Through CDO1 to Reverse Myopia Progression.
Lipid oxidation reprogramming in cancer-associated fibroblasts enhances CD8(+) T cell cytotoxicity and therapeutic response.
Increased PRSS56 expression is a causal factor and therapeutic target for human axial high myopia.
HE4 Might Participate in Extracellular Matrix Remodeling in Ovarian Cancer via Activation of Fibroblasts.
KLF5 Regulation of Exosome-Derived miR-152-3p From Bone Marrow Stem Cells Improves Ventricular Arrhythmia After Myocardial Infarction.
Tetrahedral Framework Nucleic Acids Inhibit Oxidative Stress and Cardiomyocyte Apoptosis in Doxorubicin-Induced Cardiotoxicity.
NIR-II Imaging Guided Accurate Identification of Paraspinal Muscle Degeneration Through Targeting the Lysosomal Membrane Protein Sidt2.
Salidroside Improves Periodontitis by Mitigating Inflammatory Reactions and Enhancing Osteogenic Differentiation of Human Periodontal Ligament Stem Cells.
Astragaloside IV Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells via Activating PI3K/AKT/eNOS/NO Signaling Pathway: In vitro and in vivo Study.
Irisin Mitigates Doxorubicin-Induced Cardiotoxicity by Reducing Oxidative Stress and Inflammation via Modulation of the PERK-eIF2α-ATF4 Pathway.
Effects of ADRM1 on osteoblast differentiation and mineralization in osteoporosis.
Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes.
2-Dodecyl-6-methoxycyclohexa-2,5-dien-1,4-dione alleviates liver fibrosis and improves intestinal flora and bile acid metabolism.
Dl-3-n-butylphthalide attenuates DOX-induced cardiotoxicity in mice by inhibiting Nrf2/Keap1 complex formation.
An anti-FAP-scFv-functionalized exosome-carrying hydrogel delivers SKI mRNA to fibrotic nucleus pulposus cells to alleviate intervertebral disc degeneration by regulating FOXO3.
Rapid cutaneous wound healing in nude mice by fetal skin-derived stem cells involves enhanced collagen secretion and angiogenesis.
Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis.
Efficacy and safety of pseudolaric acid B against Echinococcus multilocularis in vitro and in a murine infection model.
Spatial discovery of pyrotinib overcoming HER2-positive breast cancer resistance by breaking fibroblast-induced immune barriers.
Dl-3-n-butylphthalide attenuates acute myocardial infarction by inhibiting the binding of Nrf2/Keap1.
METTL3 Silencing Suppresses Cardiac Fibrosis Post Myocardial Infarction via m6A Modification of SMOC2.
Quercetin diminishes scleral ER stress and protein misfolding: High throughput transcriptome analysis in form-deprivation myopia of Guinea pigs.
miR-29a regulates scleral remodelling via TLR7/8-dependent inflammatory signalling in myopia.
Parathyroid glands exhibit reduced parenchymatic chief cells and increased extracellular collagen as a response to a long-term low-phosphorus diet in pigs.
Piezoelectric-IL-4 programmed regulation of immuno-microenvironment-induced mesenchymal stem cell recruitment and differentiation for bone regeneration.
HMGB1-mediated macrophage polarization to M2 phenotype promotes ureteral stricture: therapeutic potential of HMGB1 inhibitors.
Mechanism of Bao Gan Ning decoction in attenuating hepatic fibrosis via modulation of the gut microbiome and PPAR/CYP7A1-mediated bile acid metabolism.
Sustained Mg/Sr ion delivery from injectable silk fibroin hydrogels drives SCAP osteogenic differentiation.
Downregulation of HDAC9 Alleviates Autophagy Dysfunction by Inducing Acetylation of ATG4B in Metabolic Dysfunction-Associated Steatotic Liver Disease.
Farrerol ameliorates diabetic cardiomyopathy by inhibiting ferroptosis via miR-29b-3p/SIRT1 signaling pathway in endothelial cells.
Oxymatrine attenuates pulmonary fibrosis via APE1‑mediated regulation of the PINK1/Parkin pathway.
TGF-β1/IL-11 positive loop between renal tubular epithelial cell and fibroblast promotes the ectopic calcification of renal interstitial fibroblasts in rats.
Rottlerin inhibits PKCδ to attenuate pulmonary fibrosis by suppressing NLRC4/ASC-mediated pyroptosis.
Icariside II attenuates renal fibrosis through mTOR signaling modulation: an integrated approach combining network pharmacology, molecular dynamics, and in vitro validation.
Apelin-13 treats postmenopausal osteoporosis by reducing mitochondrial oxidative phosphorylation and modulating the OPG/RANK/RANKL/IGF-1 pathway.
Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling.
M2-exo promote orthodontic bone remodeling via the MeCP2-TCF20-HDAC1 axis.
A hydrogel tissue adhesive incorporating basic fibroblast growth factor-loaded liposomes accelerates cutaneous wound healing by enhancing cell proliferation, collagen synthesis and angiogenesis.
Injectable protein hydrogel microspheres with reactive oxygen species-responsive nitric oxide release for cardiac protection against ischemia/reperfusion injury.
H3K18 lactylation-hexokinase 2 positive feedback loop promotes osteogenesis of ASPCs in facial infiltrating lipomatosis.
Comprehensive analysis of extracellular matrix remodelling via cyclophilin inhibition in human models of alcohol-related liver fibrosis.
Polycystin-1 Mutant Alters Mechanotransduction in Response to Collagen and Extracellular Matrix Stiffness via Daam1-Dependent Microfilament Remodeling.
From Gene to Scar: Proteome-Wide Causal Insights into Keloid Pathogenesis and Prevention.
The TRPV4-YAP axis mediates cytoskeletal and extracellular matrix remodeling in trabecular meshwork cells as a novel glaucoma mechanism.
Curcumenol exerts anti-pulmonary fibrosis effects through modulation of the immune signature target SPP1: based on comprehensive bioinformatics and experiments validation.
SIRT1 Alleviates Oxidative Stress-Induced Mitochondrial Dysfunction and Mitochondria-Associated Membrane Dysregulation in Stress Urinary Incontinence.
Tryptanthrin alleviate lung fibrosis via suppression of MAPK/NF-κB and TGF-β1/SMAD signaling pathways in vitro and in vivo.
LncRNA NAV2-AS2 is critical for fibroblast-to-myofibroblast transition and cardiac fibrosis.
EFNA2 Mediates Stiffness-Regulated Hypopharyngeal Cancer Progression.
Engineering Antibacterial, Biocompatible, Anti-Oxidant Titanium-Based Implants Using Polyphenols-Chlorhexidine Networks for Bone Regeneration.
TiO(2) Nanotube Implants Modified with Silk Fibroin and Mesoporous Silica Nanocomposite Coatings Enable Efficient Drug Release to Promote Osteogenesis.
Loading tea polyphenols enhances the repair of human umbilical cord mesenchymal stem cell sheet after spinal cord injury.
Hypoxia-inducible factor-1 alpha (HIF-1α) inhibitor AMSP-30 m attenuates CCl(4)-induced liver fibrosis in mice by inhibiting the sonic hedgehog pathway.
Mechanoregulative hydrogel facilitates rapid scarless healing by self-adaptive control of wound niche at different stages.
Asb10 accelerates pathological cardiac remodeling by stabilizing HSP70.
Temporal Proteome Profiling of Anterior Cruciate Ligament Tear Remnants: Secretory Proteins in the Acute Phase Potentially Promote Tissue Repair.
Tetrathiomolybdate alleviates bleomycin-induced pulmonary fibrosis by reducing copper concentration and suppressing EMT.
Urolithin A enhances diabetic wound healing: Insights from parkin-mediated mitophagy in endothelial progenitor cells.
Aggressive characteristics of tumor deposits in colorectal cancer highlight the need for staging refinement in patients with 0-3 metastatic lymph nodes.
LINC00525 promotes cell proliferation and collagen expression through feedforward regulation of TGF-β signaling in hypertrophic scar fibroblasts.
Ergothioneine Ameliorates Liver Fibrosis by Inhibiting Glycerophospholipids Metabolism and TGF-β/Smads Signaling Pathway: Based on Metabonomics and Network Pharmacology.
Sacubitril/valsartan attenuates inflammation and myocardial fibrosis in Takotsubo-like cardiomyopathy.
VHL ameliorates arecoline-induced oral submucosal fibrosis by promoting HDAC6 ubiquitination and blocking NF-κB pathway.
Establishment and characterization of a novel immortalized human aortic valve interstitial cell line.
Cyanidin-3-glucoside upregulated NDRG2 through the PI3K/AKT pathway to alleviate EMT and ECM in renal fibrosis.
Triptolide combined with salvianolic acid B alleviates CCL(4)-induced liver fibrosis by suppressing the Th17/IL-17A axis.
Dietary phytosterol supplementation mitigates renal fibrosis via activating mitophagy and modulating the gut microbiota.
Neddylation of RhoA impairs its protein degradation and promotes renal interstitial fibrosis progression in diabetic nephropathy.
Expression, optimization and biological activity analysis of recombinant type XII collagen in Pichia pastoris.
P4HB, a novel succinated protein, is essential for fumarate-induced cancer metastasis.
Single-cell transcriptomics reveal the effects of chemoimmunotherapy on hypopharyngeal cancer and its tumor microenvironment.
Mast cell tryptase-PAR2 axis promotes ovarian fibrosis through RNF152-mediated stabilization of Bcl-xL.
Construction and validation of a prognostic nomogram model integrating machine learning-pathomics and clinical features in IDH-wildtype glioblastoma.
FKBP5 promotes osteogenic differentiation of mesenchymal stem cells through type-I interferon pathway Inhibition.
The KSR1/MEK/ERK signaling pathway promotes the progression of intrauterine adhesions.
Tβ4-Engineered ADSC Extracellular Vesicles Rescue Cell Senescence Through Separable Microneedle Patches for Diabetic Wound Healing.
FABP4 Inhibitor Improves Right Ventricular Fibrosis in Metabolic Syndrome- Related Pulmonary Hypertension due to Left Heart Disease in Mice.
Mechanistic exploration of Dahuang Zhechong Pill against hepatic fibrosis via integrated serum pharmacochemistry, UHPLC-ESI-QTOF-MS/MS, network pharmacology, and molecular docking with cellular and zebrafish validation.
Ameliorating Myocardial Infarction by Concurrent Pyroptosis Suppression and On-Demand Oxygen Production via Functionalized Nanocarrier.
Pannexin1 via P2rx7/amphiregulin contributes to cardiac fibrosis post myocardial infarction.
Timosaponin AIII alleviates type 2 diabetes-induced cardiomyopathy by targeting galectin-3 (LGALS3).
Secreted phosphoprotein 1 promotes the activation of keloid fibroblasts via the CD44/TGF-β1/Smad pathway.
Transcriptional and post-translational mechanisms of ECM remodeling in rotator cuff tendons under hyperlipidemic conditions.
Construction of a prostate adenocarcinoma molecular classification: integrating spatial transcriptomics with retrospective cohort validation.
Improving tendon repair through spatiotemporal modulation of TGF-β1 expression using an ultrasound-responsive hydrogel carrying siRNA-loaded nanoparticles.
Extracellular vesicle-derived lncRNA VIM-AS1 promotes diabetic wound healing by promoting glycolysis and alleviating cellular senescence.
Excessive accumulation of thioredoxin promotes osteogenic differentiation of mesenchymal stem cells of ligament in ankylosing spondylitis by upregulating autophagy levels.
N6-methyladenosine modification of SPOP relieves ferroptosis and diabetic cardiomyopathy by enhancing ubiquitination of VDAC3.
Short-term exposure to low doses of aflatoxin B1 aggravates nonalcoholic steatohepatitis by TLR4-mediated necroptosis.
GDF15 promotes osteogenic differentiation of human dental pulp stem cells by activating the TGF-β/SMAD signaling pathway.
Supplementation with carnosine, a food-derived bioactive dipeptide, alleviates dexamethasone-induced oxidative stress and bone impairment via the NRF2 signaling pathway.
Atractylenolide-III restrains cardiac fibrosis after myocardial infarction via suppression of the RhoA/ROCK1 and ERK1/2 pathway.
A new mechanism of arterial calcification in diabetes: interaction between H3K18 lactylation and CHI3L1.
Extracellular vesicles from adipose-derived stem cell alleviate diabetic cardiomyopathy by regulating Chit1/NLRP3/Caspase-1-Mediated pyroptosis.
Hydrogen sulfide attenuates disturbed flow-induced vascular remodeling by inhibiting LDHB-mediated autophagic flux.
Integrating Network Pharmacology and In Vitro Experimental Verification Revealing Bushenhuoxue Recipe Against Intrauterine Adhesions via PI3K-AKT Signaling Pathway.
Integrated UHPLC-Q-exactive orbitrap HRMS and serum pharmacochemistry for the investigation of anti-hepatic fibrosis effect of Baoganning Decoction.
Cancer-secreted exosomal miR-1246 promotes colorectal cancer liver metastasis by activating hepatic stellate cells.
Astaxanthin Prevents Glucocorticoid-Induced Femoral Head Osteonecrosis by Targeting Ferroptosis through the JAK2/STAT3 Signaling Pathway.
Role of SAA1 in Endometrial Extracellular Matrix Remodeling in Polycystic Ovary Syndrome: Implication for Pregnancy Loss.
WNT inhibitor SP5-mediated SERPING1 suppresses lung adenocarcinoma progression via TSC2/mTOR pathway.
SCGB1D4 downregulation links to fibrosis in intrauterine adhesion patients and rat models†.
PAI-1 deficiency inhibits endometrial fibrosis via modulation of the FAK/Src/ERK and AKT signalling pathways.
EXO/hydrogel system for sequential regulation of endogenous hyaline cartilage regeneration.
Whitlockite-loaded silk fibroin/polyvinyl alcohol hydrogel composited with porous tantalum scaffold enhances bone regeneration and immunomodulation via the TGF-β/NRROS signaling pathway.
Sappanone A, a potential natural inhibitor of PI3K, alleviates metabolic dysfunction-associated steatohepatitis in experimental models.
COL4A2 drives ECM remodeling and stiffness increasing to promote breast cancer metastasis via YAP signaling pathway in dECM induced models.
Heterogeneity of active mast cells, endothelial cells, and fibroblasts in hemophilic arthritis defined by synovial single-cell sequencing.
Lumican from DESC spheroids enhances odontoblastic differentiation of SCAPs.
The NAWG combinatorial strategy activates MAPK signaling to restore extracellular matrix architecture in aging skin.
Serum response factor targets Cyr61 to facilitate chronic progression after ischemic acute kidney injury through renal tubular epithelial-myofibroblast transdifferentiation.
Interleukin-27 is a multitarget regulator of fibroblast remodeling in thyroid-associated ophthalmopathy.
Multi-omics factor analysis identifies the Tensin 1-Fermitin family homologue 2-Fibronectin 1-Integrin signaling axis as a prognostic determinant in colorectal cancer.
Decreased scleral Wnt5a(hi) fibroblasts exacerbate myopia progression by disrupting extracellular matrix homeostasis in mice.
Nucleosome assembly protein-like 1 degradation-dependent novel cardioprotection mechanism of Wnt2 against ischemia‒reperfusion injury.
Improving the Culture of Human Skin Explants for Use in Preclinical Testing of Wound Healing Treatments.
Procyanidin B2 mitigate asthmatic airway remodeling by inhibiting TGF-β1-induced airway smooth muscle proliferation through ROS signaling.
Loss of Trim31 Worsens Cardiac Remodeling in a Mouse Model of Heart Failure by Enhancing the Activation of the NLRP3 Inflammasome.
Kaempferol Remodels Liver Monocyte Populations and Treats Hepatic Fibrosis in Mice by Modulating Intestinal Flora and Metabolic Reprogramming.
Dissolvable microneedle-assisted transdermal administration of diacerein nanoparticles achieved satisfactory therapeutic effects in tendon-bone insertion repair by reducing oxidative stress and inflammation.
From stem cells to skin: ADSCP6 peptide's role in transforming scar therapy.
Platelet-rich plasma-derived exosomes have the novel ability to alleviate insertional Achilles tendinopathy by promoting tenogenesis in tendon stem/progenitor cells.
Tissue-specific composite hydrogel-loaded BMSCs inhibit apoptosis and promote meniscal repair.
Zn-Based Multi-Active Framework Nanoparticles TSA-CAN-Zn Inhibit Skin Glycation via Dual Blockade of HMGB1/RAGE and AGEs/RAGE Pathways.
F-box only protein 10 protects against kidney tubulointerstitial fibrosis by inhibiting ACSL4-mediated lipid peroxidation and ferroptosis.
Folic acid-functionalized PLGA nanomedicines encapsulating echinacoside for liver cancer therapy.
Lymph nodes molecular subtypes unravel lymph nodes heterogeneity and clinical implications in colorectal cancer.
HAS1(high) cancer associated fibroblasts located at the tumor invasion front zone promote oral squamous cell carcinoma invasion via ECM remodeling.
Snhg18 regulates Yap subcellular localization to maintain bone homeostasis.
Irisolidone enhances osteoblast differentiation via the AMPK-ULK1-autophagy Axis to accelerate osteoporotic fracture repair.
Mesenteric adipose-derived exosomal TINAGL1 enhances intestinal fibrosis in Crohn's Disease via SMAD4.
Laboratory investigation of METTL7A driving MSC osteogenic differentiation through YAP1 translation enhancement via eIF4F recruitment.
Copper doped bioactive glass promotes matrix vesicles-mediated biomineralization via osteoblast mitophagy and mitochondrial dynamics during bone regeneration.
GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy.
Fibroblast derived C3 promotes the progression of experimental periodontitis through macrophage M1 polarization and osteoclast differentiation.
Aging and autophagic phenotypic changes in bone marrow mesenchymal stem cells in glucocorticoid-induced osteonecrosis.
Fabrication of 3D Biomimetic Smooth Muscle Using Magnetic Induction and Bioprinting for Tissue Regeneration.
Amlexanox Enforces Osteogenic Differentiation and Bone Homeostasis Through Inhibiting Ubiquitin-Dependent Degradation of β-Catenin.
Col1A1 as a new decoder of clinical features and immune microenvironment in ovarian cancer.
Fibroblasts facilitate lymphatic vessel formation in transplanted heart.
HIF2A mediates lineage transition to aggressive phenotype of cancer-associated fibroblasts in lung cancer brain metastasis.
Role of integrin β1 and tenascin C mediate TGF-SMAD2/3 signaling in chondrogenic differentiation of BMSCs induced by type I collagen hydrogel.
Unraveling the role of MiR-181 in skin fibrosis pathogenesis by targeting NUDT21.
Cyy-272, an indazole derivative, effectively mitigates obese cardiomyopathy as a JNK inhibitor.
Let‑7f‑5p Regulated by Hsa_circ_0000437 Ameliorates Bleomycin-Induced Skin Fibrosis.
Angiotensin receptor blocker attacks armored and cold tumors and boosts immune checkpoint blockade.
Salidroside alleviates simulated microgravity-induced bone loss by activating the Nrf2/HO-1 pathway.
NBQX mediates ventricular fibrillation susceptibility in rat models of anxiety via the Nrf2/HO-1 pathway.
Chitosan/cellulose nanocrystals/graphene oxide scaffolds as a potential pH-responsive wound dressing: Tuning physico-chemical, pro-regenerative and antimicrobial properties.
Protective effect and mechanism of lycium barbarum polysaccharide against UVB-induced skin photoaging.
Nuclear receptor 4A1 ameliorates renal fibrosis by inhibiting vascular endothelial growth factor A induced angiogenesis in UUO rats.
SLAMF8 regulates osteogenesis and adipogenesis of bone marrow mesenchymal stem cells via S100A6/Wnt/β-catenin signaling pathway.
Co-Mn Complex Oxide Nanoparticles as Potential Reactive Oxygen Species Scavenging Agents for Pulmonary Fibrosis Treatment.
The Functional Role of the Long Non-Coding RNA LINCMD1 in Leiomyoma Pathogenesis.
Astragaloside I Promotes Lipophagy and Mitochondrial Biogenesis to Improve Hyperlipidemia by Regulating Akt/mTOR/TFEB Pathway.
Construction of an interactome network among circRNA-miRNA-mRNA reveals new biomarkers in hBMSCs osteogenic differentiation.
NIR-II light based combinatorial management of hypertrophic scar by inducing autophagy in fibroblasts.
Preliminary study of the role of histone deacetylase (HDAC) in steroid-induced avascular necrosis of the femoral head induced by BMSC adipogenic differentiation.
Biodegradable Piezoelectric-Conductive Integrated Hydrogel Scaffold for Repair of Osteochondral Defects.
Nuclear translocation of SIRT4 mediates deacetylation of U2AF2 to modulate renal fibrosis through alternative splicing-mediated upregulation of CCN2.
Granzyme K(+)CD8(+) T cells interact with fibroblasts to promote neutrophilic inflammation in nasal polyps.
Sele-targeted siRNA liposome nanoparticles inhibit pathological scars formation via blocking the cross-talk between monocyte and endothelial cells: a preclinical study based on a novel mice scar model.
Zfp260 choreographs the early stage osteo-lineage commitment of skeletal stem cells.
Tumor microenvironment remodeling after neoadjuvant chemoradiotherapy in local advanced rectal cancer revealed by single-cell RNA sequencing.
Ulinastatin attenuates renal fibrosis by regulating AMPK/HIF-1α signaling pathway-mediated glycolysis.
Alarmin-loaded extracellular lipid droplets induce airway neutrophil infiltration during type 2 inflammation.
Uniaxial static strain enhances osteogenic and angiogenic potential under hypoxic conditions in distraction osteogenesis.
Identification of ROS and KEAP1-related genes and verified targets of α-hederin induce cell death for CRC.
Effects of Nanoparticle-Mediated Dihydromyricetin to Diabetic Wounds: An In Vivo Study.
Human amnion mesenchymal stem cells promote endometrial repair via paracrine, preferentially than transdifferentiation.
The Bioactive Compounds of Epimedium and Their Potential Mechanism of Action in Treating Osteoporosis: A Network Pharmacology and Experimental Validation Study.
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
Lactate facilitated mitochondrial fission-derived ROS to promote pulmonary fibrosis via ERK/DRP-1 signaling.
Neferine mitigates angiotensin II-induced atrial fibrillation and fibrosis via upregulation of Nrf2/HO-1 and inhibition of TGF-β/p-Smad2/3 pathways.
Multi-omics integration highlights the role of ubiquitination in endometriosis fibrosis.
3D Printed Porous Zirconia Biomaterials based on Triply Periodic Minimal Surfaces Promote Osseointegration In Vitro by Regulating Osteoimmunomodulation and Osteo/Angiogenesis.
An immune cell map of human lung adenocarcinoma development reveals an anti-tumoral role of the Tfh-dependent tertiary lymphoid structure.
Revealing PPP1R12B and COL1A1 as piRNA pathway genes contributing to abdominal aortic aneurysm through integrated analysis and experimental validation.
Bicyclol Alleviates Streptozotocin-induced Diabetic Cardiomyopathy By Inhibiting Chronic Inflammation And Oxidative Stress.
CircZfp644-205 inhibits osteoblast differentiation and induces apoptosis of pre-osteoblasts via sponging miR-455-3p and promoting SMAD2 expression.
Bioactive compound schaftoside from Clinacanthus nutans attenuates acute liver injury by inhibiting ferroptosis through activation the Nrf2/GPX4 pathway.
Multiomic analysis of monocyte-derived alveolar macrophages in idiopathic pulmonary fibrosis.
Exosomal miR-17-5p derived from epithelial cells is involved in aberrant epithelium-fibroblast crosstalk and induces the development of oral submucosal fibrosis.
Silibinin attenuates TGF-β2-induced fibrogenic changes in human trabecular meshwork cells by targeting JAK2/STAT3 and PI3K/AKT signaling pathways.
The EPRS-ATF4-COLI pathway axis is a potential target for anaplastic thyroid carcinoma therapy.
Adiponectin inhibits ROS/NLRP3 inflammatory pathway through FOXO3A to ameliorate oral submucosal fibrosis.
Dendrobine Ameliorates Glucocorticoid-Induced Osteoporosis by Promoting Osteogenesis through JNK/p38 MAPK Pathway Activation and GR Nuclear Translocation Inhibition.
Varied cellular abnormalities in thin vs. normal endometrium in recurrent implantation failure by single-cell transcriptomics.
The miR-15b-5p/miR-379-3p-FOXO axis regulates cell cycle and apoptosis in scleral remodeling during experimental myopia.
Zhen-wu-tang protects against myocardial fibrosis by inhibiting M1 macrophage polarization via the TLR4/NF-κB pathway.
The ANGPTL4-HIF-1α loop: a critical regulator of renal interstitial fibrosis.
Single-Cell RNA Transcriptome of the Human Endometrium Reveals Epithelial Characterizations Associated with Recurrent Implantation Failure.
Uric acid promotes interleukin-17 expression to cause kidney injury.
Metabolic reprogramming driven by EZH2 inhibition depends on cell-matrix interactions.
Lactate accumulation induced by Akt2-PDK1 signaling promotes pulmonary fibrosis.
Biomimetic cryogel promotes the repair of osteoporotic bone defects through altering the ROS niche via down-regulating the ROMO1.
Role of IFITM2 in osteogenic differentiation of C3H10T1/2 mesenchymal stem cells.
Single-Nucleus RNA Sequencing Unravels Early Mechanisms of Human Becker Muscular Dystrophy.
Scaffold loaded LPS-hUCMSC-sEVs promote Osteo/odontogenic differentiation and angiogenic potential of hDPSCs.
Geniposide alleviates heart failure with preserved ejection fraction in mice by regulating cardiac oxidative stress via MMP2/SIRT1/GSK3β pathway.
Calpain-1 Up-Regulation Promotes Bleomycin-Induced Pulmonary Fibrosis by Activating Ferroptosis.
Single-cell RNA transcriptomics reveals Du-Zhong-Wan promotes osteoporotic fracture healing via YAP/β-catenin/VEGF axis in BMSCs.
A 0.2 T-0.4 T Static Magnetic Field Improves the Bone Quality of Mice Subjected to Hindlimb Unloading and Reloading Through the Dual Regulation of BMSCs via Iron Metabolism.
SPDEF ameliorates UUO-induced renal fibrosis by transcriptional activation of NR4A1.
Tubuloside A alleviates postmyocardial infarction cardiac fibrosis by inhibiting TGM2: Involvement of inflammation and mitochondrial pathway apoptosis.
Myricetin Alleviates Silica-Mediated Lung Fibrosis via PPARγ-PGC-1α Loop and Suppressing Mitochondrial Senescence in Epithelial Cells.
Magnetically Induced Anisotropic Microstructures on Polyethylene Glycol Hydrogel Facilitate BMSC Alignment and Osteogenic Differentiation.
Exome-wide association study identifies KDELR3 mutations in extreme myopia.
Expression of insulin-like growth factor binding protein 5 in the vaginal wall tissues of older women with pelvic organ prolapse.
ENG is a Biomarker of Prognosis and Angiogenesis in Liver Cancer, and Promotes the Differentiation of Tumor Cells into Vascular ECs.
Cryptotanshinone alleviates liver fibrosis via inhibiting STAT3/CPT1A-dependent fatty acid oxidation in hepatic stellate cells.
Phosphodiesterase type 5 inhibitor tadalafil reduces prostatic fibrosis via MiR-3126-3p/FGF9 axis in benign prostatic hyperplasia.
System analysis based on weighted gene co-expression analysis identifies SOX7 as a novel regulator of hepatic stellate cell activation and liver fibrosis.
Suppression of NUPR1 in fibroblast-like synoviocytes reduces synovial fibrosis via the Smad3 pathway.
Chronic exposure to BDE-47 aggravates acute pancreatitis and chronic pancreatitis by promoting acinar cell apoptosis and inflammation.
Identification of a circulating three-miRNA panel for the diagnosis of primary open angle glaucoma.
PM2.5 exposure-induced senescence-associated secretory phenotype in airway smooth muscle cells contributes to airway remodeling.
Cellular senescence and metabolic reprogramming model based on bulk/single-cell RNA sequencing reveals PTGER4 as a therapeutic target for ccRCC.
Comparison studies identify mesenchymal stromal cells with potent regenerative activity in osteoarthritis treatment.
Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS.
Downregulation of KIAA1199 alleviated the activation, proliferation, and migration of hepatic stellate cells by the inhibition of epithelial-mesenchymal transition.
GLIS2 Prevents Hepatic Fibrosis by Competitively Binding HDAC3 to Inhibit Hepatic Stellate Cell Activation.
Chrysin ameliorates synovitis and fibrosis of osteoarthritic fibroblast-like synoviocytes in rats through PERK/TXNIP/NLRP3 signaling.
Thymoquinone affects the gemcitabine sensitivity of pancreatic cancer by regulating collagen via hypoxia inducible factor-1α.
A novel signature of aging-related genes associated with lymphatic metastasis for survival prediction in patients with bladder cancer.
Extracellular ATP-induced calcium oscillations regulating the differentiation of osteoblasts through aerobic oxidation metabolism pathways.
α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure.
Photobiomodulation at 660 nm promotes collagen synthesis via downregulation of HIF-1α expression without photodamage in human scleral fibroblasts in vitro in a hypoxic environment.
SIRT3 regulates mitophagy in liver fibrosis through deacetylation of PINK1/NIPSNAP1.
A multifunctional polydopamine/genipin/alendronate nanoparticle licences fibrin hydrogels osteoinductive and immunomodulatory potencies for repairing bone defects.
PDK4 facilitates fibroblast functions and diabetic wound healing through regulation of HIF-1α protein stability and gene expression.
Fu-Zheng-Tong-Luo formula promotes autophagy and alleviates idiopathic pulmonary fibrosis by controlling the Janus kinase 2/signal transducer and activator of transcription 3 pathway.
The Dual-Mode Transition of Myofibroblasts Derived from Hepatic Stellate Cells in Liver Fibrosis.
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
Dihydroartemisinin inhibits the activation and proliferation of hepatic stellate cells by regulating miR‑29b‑3p.
Schistosome egg antigen stimulates the secretion of miR-33-carrying extracellular vesicles from macrophages to promote hepatic stellate cell activation and liver fibrosis in schistosomiasis.
GATA6 triggers fibroblast activation and tracheal fibrosis through the Wnt/β-catenin pathway.
Yishen Tongluo formula alleviates diabetic kidney disease through regulating Sirt6/TGF-β1/Smad2/3 pathway and promoting degradation of TGF-β1.
Taohong Siwu Decoction enhances human bone marrow mesenchymal stem cells proliferation, migration and osteogenic differentiation via VEGF-FAK signaling in vitro.
Hypoxia-Induced Kidney Injury in Newborn Rats.
Tabersonine attenuates obesity-induced renal injury via inhibiting NF-κB-mediated inflammation.
Ellagic acid inhibits CDK12 to increase osteoblast differentiation and alleviate osteoporosis in hindlimb-unloaded and ovariectomized mice.
Silencing of NOTCH3 Signaling in Meniscus Smooth Muscle Cells Inhibits Fibrosis and Exacerbates Degeneration in a HEYL-Dependent Manner.
Macrophage Dectin-1 mediates Ang II renal injury through neutrophil migration and TGF-β1 secretion.
Total flavonoid extract from Dracocephalum moldavica L. improves pulmonary fibrosis by reducing inflammation and inhibiting the hedgehog signaling pathway.
Fibroblast growth factor 10 delays the progression of osteoarthritis by attenuating synovial fibrosis via inhibition of IL-6/JAK2/STAT3 signaling in vivo and in vitro.
LAMP2A regulates the balance of mesenchymal stem cell adipo-osteogenesis via the Wnt/β-catenin/GSK3β signaling pathway.
Identification of Immune Infiltration in Odontogenic Keratocyst by Integrated Bioinformatics Analysis.
Metformin suppressed tendon injury-induced adhesion via hydrogel-nanoparticle sustained-release system.
Atractylenolide III Ameliorates Bile Duct Ligation-Induced Liver Fibrosis by Inhibiting the PI3K/AKT Pathway and Regulating Glutamine Metabolism.
Sodium houttuyfonate against cardiac fibrosis attenuates isoproterenol-induced heart failure by binding to MMP2 and p38.
Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression.
20-Hydroxytetraenoic acid induces hepatic fibrosis via the TGF-β1/Smad3 signaling pathway.
The m6A demethylase FTO promotes keloid formation by up-regulating COL1A1.
Alamandine/MrgD axis prevents TGF-β1-mediated fibroblast activation via regulation of aerobic glycolysis and mitophagy.
Effect of stretch frequency on osteogenesis of periodontium during periodontal ligament distraction.
Autophagy loss impedes cancer-associated fibroblast activation via downregulating proline biosynthesis.
LncRNA H19-EZH2 interaction promotes liver fibrosis via reprogramming H3K27me3 profiles.
Obstructive sleep apnea promotes the progression of lung cancer by modulating cancer cell invasion and cancer-associated fibroblast activation via TGFβ signaling.
Degradation Adaptability Assessment of Semisolid Powder Molded Mg-Zn-Mn Alloys for Orthopedic Applications.
Neuropilin 1 promotes unilateral ureteral obstruction-induced renal fibrosis via RACK1 in renal tubular epithelial cells.
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
Dectin-1 deficiency alleviates diabetic cardiomyopathy by attenuating macrophage-mediated inflammatory response.
LncRNA DGCR5-encoded polypeptide RIP aggravates SONFH by repressing nuclear localization of β-catenin in BMSCs.
Knockdown of FBLN2 suppresses TGF-β1-induced MRC-5 cell migration and fibrosis by downregulating VTN.
P4HA1, transcriptionally activated by STAT1, promotes esophageal cancer progression.
Activation of NRF2 Signaling Pathway Delays the Progression of Hyperuricemic Nephropathy by Reducing Oxidative Stress.
Single-Cell RNA-Sequencing Reveals the Cellular and Genetic Heterogeneity of Skin Scar to Verify the Therapeutic Effects and Mechanism of Action of Dispel-Scar Ointment in Hypertrophic Scar Inhibition.
Cigarette Smoke Exposure Increases Glucose-6-phosphate Dehydrogenase, Autophagy, Fibrosis, and Senescence in Kidney Cells In Vitro and In Vivo.
Mechanism of Action of Zhi Gan Cao Decoction for Atrial Fibrillation and Myocardial Fibrosis in a Mouse Model of Atrial Fibrillation: A Network Pharmacology-Based Study.
miR-486-5p Restrains Extracellular Matrix Production and Oxidative Damage in Human Trabecular Meshwork Cells by Targeting TGF-β/SMAD2 Pathway.
Ganfule capsule alleviates bile duct ligation-induced liver fibrosis in mice by inhibiting glutamine metabolism.
QiShenYiQi Pill Ameliorates Cardiac Fibrosis After Pressure Overload-Induced Cardiac Hypertrophy by Regulating FHL2 and the Macrophage RP S19/TGF-β1 Signaling Pathway.
Beneficial Effect of Edoxaban on Preventing Atrial Fibrillation and Coagulation by Reducing Inflammation via HBG1/HBD Biomarkers.
Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway.
Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics.
Blockade of phosphotyrosine pathways suggesting SH2 superbinder as a novel therapy for pulmonary fibrosis.
LARP6 Regulates Keloid Fibroblast Proliferation, Invasion, and Ability to Synthesize Collagen.
Knockdown of FOXA1 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the ERK1/2 signalling pathway.
Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury.
miR-182-5p attenuates Schistosoma japonicum-induced hepatic fibrosis by targeting tristetraprolin.
Carbon tetrachloride exposure induces ovarian damage through oxidative stress and inflammatory mediated ovarian fibrosis.
Si-Wu-Tang ameliorates bile duct ligation-induced liver fibrosis via modulating immune environment.
Proteogenomic insights into the biology and treatment of pancreatic ductal adenocarcinoma.
Macrophage-targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis.
Intracellular hydroxyproline imprinting following resolution of bleomycin-induced pulmonary fibrosis.
ALKBH5 ameliorated liver fibrosis and suppressed HSCs activation via triggering PTCH1 activation in an m(6)A dependent manner.
Host liver-derived extracellular vesicles deliver miR-142a-3p induces neutrophil extracellular traps via targeting WASL to block the development of Schistosoma japonicum.
Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis.
Masquelet technique: Effects of vancomycin concentration on quality of the induced membrane.
Overexpression of G Protein-Coupled Receptor 40 Protects Obesity-Induced Cardiomyopathy Through the SIRT1/LKB1/AMPK Pathway.
Suppression of the Inhibitory Effect of circ_0036176-Translated Myo9a-208 on Cardiac Fibroblast Proliferation by miR-218-5p.
ZIC5 promotes human hepatocellular carcinoma cell proliferation through upregulating COL1A1.
Patient-derived microphysiological model identifies the therapeutic potential of metformin for thoracic aortic aneurysm.
Hypoxia-Induced Scleral HIF-2α Upregulation Contributes to Rises in MMP-2 Expression and Myopia Development in Mice.
Sustained release of naringin from silk-fibroin-nanohydroxyapatite scaffold for the enhancement of bone regeneration.
Tartrate-resistant acid phosphatase 5 promotes pulmonary fibrosis by modulating β-catenin signaling.
Bmal1 inhibits phenotypic transformation of hepatic stellate cells in liver fibrosis via IDH1/α-KG-mediated glycolysis.
Multi-omics analyses reveal the mechanisms of Arsenic-induced male reproductive toxicity in mice.
Acacetin alleviates myocardial ischaemia/reperfusion injury by inhibiting oxidative stress and apoptosis via the Nrf-2/HO-1 pathway.
Heat shock protein Hspa13 regulates endoplasmic reticulum and cytosolic proteostasis through modulation of protein translocation.
A silk fibroin/chitosan/nanohydroxyapatite biomimetic bone scaffold combined with autologous concentrated growth factor promotes the proliferation and osteogenic differentiation of BMSCs and repair of critical bone defects.
IL-22 inhibits bleomycin-induced pulmonary fibrosis in association with inhibition of IL-17A in mice.
Investigation of the Therapeutic Effect of Total Alkaloids of Corydalis saxicola Bunting on CCl(4)-Induced Liver Fibrosis in Rats by LC/MS-Based Metabolomics Analysis and Network Pharmacology.
Inhibition of BRD4 decreases fibrous scarring after ischemic stroke in rats by inhibiting the phosphorylation of Smad2/3.
Long noncoding RNA GAS5 inhibits LX-2 cells activation by suppressing NF-κB signalling through regulation of the miR-433-3p/TLR10 axis.
CeO(2) nanoparticles induce pulmonary fibrosis via activating S1P pathway as revealed by metabolomics.
18beta-glycyrrhetinic acid induces ROS-mediated apoptosis to ameliorate hepatic fibrosis by targeting PRDX1/2 in activated HSCs.
Circ_0047339 promotes the activation of fibroblasts and affects the development of urethral stricture by targeting the miR-4691-5p/TSP-1 axis.
Evaluation of HZX-960, a novel DCN1-UBC12 interaction inhibitor, as a potential antifibrotic compound for liver fibrosis.
Strontium doped mesoporous silica nanoparticles accelerate osteogenesis and angiogenesis in distraction osteogenesis by activation of Wnt pathway.
Weighted correlation network analysis identifies FN1, COL1A1 and SERPINE1 associated with the progression and prognosis of gastric cancer.
Chinese Herbal Medicine Suyin Detoxification Granule Inhibits Pyroptosis and Epithelial-Mesenchymal Transition by Downregulating MAVS/NLRP3 to Alleviate Renal Injury.
Costunolide Loaded in pH-Responsive Mesoporous Silica Nanoparticles for Increased Stability and an Enhanced Anti-Fibrotic Effect.
Macrophage exosomes transfer angiotensin II type 1 receptor to lung fibroblasts mediating bleomycin-induced pulmonary fibrosis.
Ppic modulates CCl(4)-induced liver fibrosis and TGF-β-caused mouse hepatic stellate cell activation and regulated by miR-137-3p.
Identification of collagen genes related to immune infiltration and epithelial-mesenchymal transition in glioma.
Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-βRI/Smad Signaling.
Apigenin protects mice against 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced cholestasis.
Phgdh serves a protective role in Il‑1β induced chondrocyte inflammation and oxidative‑stress damage.
Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats.
Nicotinamide mononucleotide attenuates isoproterenol-induced cardiac fibrosis by regulating oxidative stress and Smad3 acetylation.
Quercetin prevents isoprenaline-induced myocardial fibrosis by promoting autophagy via regulating miR-223-3p/FOXO3.
Radiation‑induced dysfunction of energy metabolism in the heart results in the fibrosis of cardiac tissues.
DNMT1-Induced miR-152-3p Suppression Facilitates Cardiac Fibroblast Activation in Cardiac Fibrosis.
Kaposi's sarcoma-associated herpesvirus vFLIP promotes MEndT to generate hybrid M/E state for tumorigenesis.
Dickkopf 3: a Novel Target Gene of miR-25-3p in Promoting Fibrosis-Related Gene Expression in Myocardial Fibrosis.
Diverging targets mediate the pathological roleof miR-199a-5p and miR-199a-3p by promoting cardiac hypertrophy and fibrosis.
Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.
Expression of collagen type 1 alpha 1 indicates lymph node metastasis and poor outcomes in squamous cell carcinomas of the lung.
Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.
Low-magnitude vibration induces osteogenic differentiation of bone marrow mesenchymal stem cells via miR-378a-3p/Grb2 pathway to promote bone formation in a rat model of age-related bone loss.
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl(4)-induced liver injury mouse model.
Sustained delivery of PlGF-2(123-144*)-fused BMP2-related peptide P28 from small intestinal submucosa/polylactic acid scaffold material for bone tissue regeneration.
Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis.
Novel role of the clustered miR-23b-3p and miR-27b-3p in enhanced expression of fibrosis-associated genes by targeting TGFBR3 in atrial fibroblasts.
Autophagy Attenuates Angiotensin II-Induced Pulmonary Fibrosis by Inhibiting Redox Imbalance-Mediated NOD-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation.
Involvement of Smad3 pathway in atrial fibrosis induced by elevated hydrostatic pressure.
The effect of different hydroxyapatite microparticles on the osteogenic differentiation of MC3T3-E1 preosteoblasts.
LncRNA-ATB/microRNA-200a/β-catenin regulatory axis involved in the progression of HCV-related hepatic fibrosis.
Crucial Role of miR-433 in Regulating Cardiac Fibrosis.
Angiotensin(1-7) attenuated Angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H2O2-activated NLRP3 inflammasome/IL-1β/Smad circuit.
MicroRNA-130a and -130b enhance activation of hepatic stellate cells by suppressing PPARγ expression: A rat fibrosis model study.
Lei Y, Ma X, Jin X, He Y, Yang J, Zhao Y, Chen J, Gao T
PloS one 2026;21(3):e0344168
PloS one 2026;21(3):e0344168
Bladder cancer-induced CVD mortality: Role of CAPG protein.
Shen J, Zhao Z, Li Z, Wang R
PloS one 2026;21(2):e0338101
PloS one 2026;21(2):e0338101
Oxidative modification of skin collagen.
Paculová V, Lenobel R, Prasad A, Pospíšil P
International journal of biological macromolecules 2026 May;363:152174
International journal of biological macromolecules 2026 May;363:152174
AURKA Activates FOXO3a to Form a Positive Feedback Loop in the Proliferation and Migration of Keloid Fibroblasts.
Chu X, Sun J, Dai S, Liang Y, Qian X, Xu J, Zhang J
Advances in wound care 2026 Mar;15(3):168-180
Advances in wound care 2026 Mar;15(3):168-180
Ascorbic Acid Modulates Collagen Properties in Glucocorticoid-Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation.
Curtis M, Kim Y, Patil R, Zhang X, Jayatilake M, Bulgin O, Lialios P, Surrency S, Tarrah S, Lazaris AK, Grafton A, Williams J 4th, Nouraie SB, Bizaki M, Xeron P, Van Keuren E, Seppala JE, Laiakis EC, Kitlinska JB, Alimperti S
Advanced healthcare materials 2026 Mar;15(12):e02606
Advanced healthcare materials 2026 Mar;15(12):e02606
JOSD2 alleviates hypertensive renal disease through deubiquitinating AKT in renal tubular epithelial cells.
Fan S, Zhao Y, Li L, Zhao Q, Fang Z, Xu D, Shao J, Zhao Y, Liang G, He X, Zhu H, Wang Y
Cellular signalling 2026 Mar;139:112330
Cellular signalling 2026 Mar;139:112330
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
Xie X, Bi S, Su B, Zhou R, Li X, Yan Z, Zhou X, Wang F, Yu T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e17257
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e17257
The m(5)C demethylase TET1 is identified as a key regulator of scleral remodeling in myopia.
Jia S, Yang L, Wei P, Yu J, Han G, Wang Y
Clinical epigenetics 2026 Mar 9;18(1)
Clinical epigenetics 2026 Mar 9;18(1)
WDR63 enhances the chondrogenic differentiation and regenerative potential of stem cell from apical papilla by facilitating vimentin function to promote mitochondrial fission.
Zhou J, Cao Y, Sun Z, Huang Y, Zhu M, Fan Z
Stem cell research & therapy 2026 Mar 8;17(1)
Stem cell research & therapy 2026 Mar 8;17(1)
Evaluation of a 3,5-diethoxycarbonyl-1,4-dihydrocollidine diet-induced mouse model in a comparative experimental study of portal hypertension.
Zhao JB, Wu ZH, Lin JY, Luo GQ, Zhang CH, Wu GB, Fan Q, Qi XL, Huo HZ, Yu JW, Li HJ, Zheng L, Luo M
World journal of gastroenterology 2026 Mar 7;32(9):114207
World journal of gastroenterology 2026 Mar 7;32(9):114207
The CDO1-ACSM3 Axis Mediates Renal Tubule Lipid Deposition and Injury by Causing Mitochondrial Dysfunction in Lupus Nephritis.
Zhang Z, Liu J, Liu Y, Wang L, Li Z, Dong Y, Tian Y, Miao X, Liu Q, Zhang W, Guo H, Xing L, Yang L, Feng X, Liu S
Cells 2026 Mar 4;15(5)
Cells 2026 Mar 4;15(5)
Glutamine-dependent changes in fibroblast-derived extracellular matrix dictate cancer cell behavior.
Guillard J, Stradley J, Turan K, Storl-Desmond MR, Lin S, Huang YC, Forti KM, Weber CR, Schwӧrer S
Matrix biology : journal of the International Society for Matrix Biology 2026 Mar 25;
Matrix biology : journal of the International Society for Matrix Biology 2026 Mar 25;
GDF15-Treated iPSC-MSC-Derived Exosomes Alleviate Fibrosis Post-Myocardial Infarction via Repression of the MFAP4/ERK/Drp1 Axis.
Qiu J, Han Q, Shen Y, Yang Q, Li Z, Hong Y, Zhao J, Lin F, Ma K, Hu B, Liang X, Zhang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 15;40(5):e71621
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 15;40(5):e71621
Multi-omics and AI-guided discovery and validation of sisomicin as a COPA-targeting agent for pathological scar inhibition.
Li P, Luo Z, Ali M, Li J, Qi F
Burns : journal of the International Society for Burn Injuries 2026 Jun;52(5):108015
Burns : journal of the International Society for Burn Injuries 2026 Jun;52(5):108015
Class Effect of SGLT2 Inhibitors Against Doxorubicin-Induced Cardiotoxicity via Regulating Adenosine Kinase Mediated-Cardiac Oxidative Stress.
Yan J, Lin K, Dai S, Zhang Y, Zheng R, Shi S, Tang Z, Lai X, Huang W, Su L
Cardiovascular drugs and therapy 2026 Jun;40(3):971-985
Cardiovascular drugs and therapy 2026 Jun;40(3):971-985
Kaempferide alleviates glucocorticoid-induced osteoporosis by targeting ferroptosis through the GSK3β/Nrf-2/GPX4 pathway.
Wu ZH, Han LJ, Zhang JX, Lin YZ, Fang X, Guo YF, Jin C, Guo XS, Chen L
International immunopharmacology 2026 Jun 15;179:116601
International immunopharmacology 2026 Jun 15;179:116601
DNA tetrahedron-mediated vascular targeted delivery of astragaloside IV enhances distraction osteogenesis via PI3K/AKT/FOXO pathway.
Feng Y, Fu H, Zhu P, Hong S, Shang Y, Chen Y, Wei H, Wu H, Huang X, Jiang W, Wang X
Biomaterials 2026 Jul;330:124040
Biomaterials 2026 Jul;330:124040
Deficiency of Med1 in keratinocytes augments dermal fibrosis and inflammation in scleroderma.
Luo J, Kang Y, Zhang Z, Zhang E, Huang J, Zhu Q, Guo Q, Song S, Wang B, Li M, Yuan Q, Li H, Zhao D, Chen H, Wang S, Li Y, Zhang B, He J, Hu L
International immunopharmacology 2026 Jul 15;181:116667
International immunopharmacology 2026 Jul 15;181:116667
Asymmetrical paravertebral muscles fibrosis causes progression of adolescent idiopathic scoliosis via myostatin signalling in fibro-adipogenic progenitors.
Sun H, Huang Y, Zhou H, Chen H, Dai J, Zhao J, Huang X, Cai H, Shen J
Journal of orthopaedic translation 2026 Jan;56:101027
Journal of orthopaedic translation 2026 Jan;56:101027
High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE(‑/‑) mice via the NAD(+)‑mediated SIRT1/MFN2 pathway.
Gao S, Yao W, Yang J, Liu Y, Pei Z
Molecular medicine reports 2026 Jan;33(1)
Molecular medicine reports 2026 Jan;33(1)
Biomimetic nanoplatforms for combined DDR2 inhibition and photothermal therapy in dense breast cancer treatment.
Chen Y, Yu Y, Fan Y, Lu W, Wei Y, Wu J, Ruan B, Wan Z, Zhao Y, Xie K, Jie W, Zheng S
Biomaterials 2026 Jan;324:123497
Biomaterials 2026 Jan;324:123497
CSB6B attenuates renal inflammation and fibrosis by inhibiting the activation of NLRP3 inflammasome through the NLRP3/Caspase-1/GSDMD/IL-1β signaling pathway.
Chen S, Zhu Y, Chen T, Xu Y, Fan Q
Pathology, research and practice 2026 Jan;277:156286
Pathology, research and practice 2026 Jan;277:156286
Yujie recipe attenuates bleomycin-induced pulmonary fibrosis via suppressing NF-κB/NLRP3 signaling in a Nrf2-dependent manner.
Qin L, Zhao B, Xiong Y, Chen L, Qi S, Ma Y, Zeng H, Song Y, Liu W, Tian T, Ge G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157607
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157607
Spil-mediated sEH overexpression contributes to the senescence of alveolar epithelial cells during pulmonary fibrosis in mice.
Zhang CY, Zhong WJ, Yang JT, Qiu YL, Sha HX, Ou AJ, Liu YB, Huang XT, Zhou Y, Duan JX, Guan CX
Journal of molecular medicine (Berlin, Germany) 2026 Jan 7;104(1):25
Journal of molecular medicine (Berlin, Germany) 2026 Jan 7;104(1):25
Isolation of Chicken Intestinal Glial Cells and Their Transcriptomic Response to LPS.
Chen J, Zhang W, Tian X, Zhang F, Xu C
Biology 2026 Jan 25;15(3)
Biology 2026 Jan 25;15(3)
Microneedle-delivered ROS-adaptive asiatic acid nanoparticles promote scarless repair via remodeling the pathological microenvironment.
Zhang Y, Tang X, Ma Y, Qiu Y, Wu X, Wu Y, Zeng L, Chen L, Wu H, Zheng Y, Xie J, Liang G, Yin L
Journal of nanobiotechnology 2026 Jan 24;24(1):171
Journal of nanobiotechnology 2026 Jan 24;24(1):171
Mechanism of Curcumin in the Treatment of Intrauterine Adhesions Based on Network Pharmacology, Molecular docking, and Experimental Validation.
Li Q, Zhang Y, Shen H, Wang Z, Huang J, Tang S, Chen P, Zhi Z
Biochemical genetics 2026 Feb;64(1):591-610
Biochemical genetics 2026 Feb;64(1):591-610
Synergistic neuroprotective effects of the ROCK inhibitor Y27632 and atorvastatin in optineurin-E50K-mutant mice through inhibition of scleral fibroblast transdifferentiation.
Zhu X, Liu X, Xu X, Ding Z, Zhang S, Wang Q, Zhang D, Qiu L, Chen S, Du M, Yuan H, Song W
Experimental eye research 2026 Feb;263:110760
Experimental eye research 2026 Feb;263:110760
Rabeprazole attenuates fibrosis by modulating SMAD3 linker region phosphorylation.
Li L, Liang Z, Fan L, Cao Y, Tang X, Chen J
Biomedical reports 2026 Feb;24(2):25
Biomedical reports 2026 Feb;24(2):25
Oxidative Fragmentation of Collagen in Skin: Relevance to Skin Aging and Skin Diseases.
Paculová V, Prasad A, Pospíšil P
The Journal of investigative dermatology 2026 Feb;146(2):550-554.e2
The Journal of investigative dermatology 2026 Feb;146(2):550-554.e2
A Biomimetic Norepinephrine-Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical-Sized Bone Defects.
Ren Z, Wu Z, Wu A, Zhang H, Lu J, Zhang J, Weng J, Zhang J, Chen S, Tan H, Guo T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e18807
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e18807
Integrated network toxicology and multi-omics analysis reveals the role of tobacco-specific carcinogen NNK in idiopathic pulmonary fibrosis pathogenesis.
Lai Y, Kuang Z, Zhou W, Zhou A, Jiang J, Zhang X, Liu S, Hou L, Li X, Cui W, Wang Z, Duan M, Zhang C, Duan C
Respiratory research 2026 Feb 28;27(1)
Respiratory research 2026 Feb 28;27(1)
A pan-cancer single-cell transcriptomic atlas of human bone metastases.
Wang S, Ma F, Wang D, Yu Q, Zheng H, Chen Z, Zhao S, Xu L, Ye Q, Tan Y, Huang W, Sun Z, Wu Z, Cai W, Fang M, Cheng M, Ji Y, Zhang Y, Gu B, Song S, Chen Y, Zhang J, Shao Y, Yan W, Sun Y
Cell reports. Medicine 2026 Feb 17;7(2):102583
Cell reports. Medicine 2026 Feb 17;7(2):102583
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
Shen Y, Zhang M, Yang T, Wu Y, Qiu Y, Zhang L, Li F, Chen M, Chen Q, Wei W, Li H, Shen Y
Cellular & molecular biology letters 2026 Feb 11;31(1):22
Cellular & molecular biology letters 2026 Feb 11;31(1):22
EP300 attenuates ferroptosis and stimulates proliferation, migration, and fibrosis of keloid fibroblasts via YY1/GPX4 axis.
Jin J, Wang K, Lu C, Yao C, Xie F
Cell cycle (Georgetown, Tex.) 2026 Dec;25(1):1-16
Cell cycle (Georgetown, Tex.) 2026 Dec;25(1):1-16
Phosphoglucose isomerase directs the inflammatory response, calcium influx and fibroblast migration in keloids.
Lu YY, Lu CC, Wang WT, Wu CH
Future science OA 2026 Dec;12(1):2615968
Future science OA 2026 Dec;12(1):2615968
A translational systems medicine approach to devising nanotherapeutics for targeted intervention of MASLD.
Luo Z, Wu J, Xu B, Wu D, Zhong Y, Hao M, Xu Y, Yang J, Wang Y, Lauschke VM, Ying S, Cheng N
Biomaterials 2026 Aug;331:124089
Biomaterials 2026 Aug;331:124089
Bioinspired scaffold recapitulating chondrogenic ontogeny and microenvironment for functional cartilage regeneration.
Yu T, Sun X, Liu Y, Dou Y, Tian Y, Zhang Y, Wang G, Wang L, Han J, Li X, Cheng X, Li H, Pan H, Yang L, Zhao Y, Yang Q
Bioactive materials 2026 Apr;58:531-549
Bioactive materials 2026 Apr;58:531-549
Upregulation of PLOD2 expression promotes the development of psoriasis: A connection between keratinocytes and fibroblasts.
Xian N, Zhang Z, Bai H, Zheng Y
International journal of biological macromolecules 2026 Apr;356:151539
International journal of biological macromolecules 2026 Apr;356:151539
Novel transcription factor zinc finger 514 suppresses lung adenocarcinoma progression and enhances cisplatin sensitivity via transcriptional repression of COL1A1.
Sun S, Ma G, Cheng L, Zhang H, Fan G, Wu L, Zhang X, Xue F, Fu T, Ji X, Wan Q, Liu Y
British journal of cancer 2026 Apr 9;
British journal of cancer 2026 Apr 9;
Wnt/OPG signaling axis drives ectopic mandibular regeneration: Mechanism mediated by tibial periosteal stem cell sheets.
Huang L, Xie R, Pu J, Shao S, Wang W
Tissue & cell 2026 Apr 23;102:103542
Tissue & cell 2026 Apr 23;102:103542
Vitamin D attenuates the progression of pulmonary fibrosis via inhibiting thymidine kinase 1/PFKFB3-driven glycolysis.
Yang H, Zhang L, Han M, Zhu K, Guo X, Yang W, Xu Q
Journal of translational medicine 2026 Apr 22;24(1)
Journal of translational medicine 2026 Apr 22;24(1)
Citicoline Restores Endoplasmic Reticulum Homeostasis by Regulating Oxidative Stress Through CDO1 to Reverse Myopia Progression.
Wu P, He S, Zhang L, Li H, Wu J, Yi K, Sun Q, Hu K, Wan W
Antioxidants & redox signaling 2026 Apr 15;:15230864261443857
Antioxidants & redox signaling 2026 Apr 15;:15230864261443857
Lipid oxidation reprogramming in cancer-associated fibroblasts enhances CD8(+) T cell cytotoxicity and therapeutic response.
Ma Z, Wang Y, Wang W, Sun W, Wang R, Ding X, Chen Z, Li X, Li Z, Ye Y, Mao Y, Yin J, Li G, He RR, Liang X, Liu Z
Cancer cell 2026 Apr 13;44(4):743-759.e8
Cancer cell 2026 Apr 13;44(4):743-759.e8
Increased PRSS56 expression is a causal factor and therapeutic target for human axial high myopia.
Wu B, Zeng W, Tang K, Xiong J, Mo X, Fu Q, Fu D, Chu R, Zhao G, Lu L, Wang Z, Wu L, Yu Z, Zhou X, Wang H
Cell research 2026 Apr 1;
Cell research 2026 Apr 1;
HE4 Might Participate in Extracellular Matrix Remodeling in Ovarian Cancer via Activation of Fibroblasts.
Liu Y, Liu B, Gao H, Wang J, Duan J, Huang X, Liu Y, Huang Y, Liao W, Li R, Linghu H
Oncology research 2025;34(1):18
Oncology research 2025;34(1):18
KLF5 Regulation of Exosome-Derived miR-152-3p From Bone Marrow Stem Cells Improves Ventricular Arrhythmia After Myocardial Infarction.
Wu C, Zou XY, Jiang YW, Lin DW, Jiang F, Wang YS
Stem cells international 2025;2025:5572221
Stem cells international 2025;2025:5572221
Tetrahedral Framework Nucleic Acids Inhibit Oxidative Stress and Cardiomyocyte Apoptosis in Doxorubicin-Induced Cardiotoxicity.
Pan H, Ye Q, Li Y, Ma L, Ni Y
International journal of nanomedicine 2025;20:9275-9289
International journal of nanomedicine 2025;20:9275-9289
NIR-II Imaging Guided Accurate Identification of Paraspinal Muscle Degeneration Through Targeting the Lysosomal Membrane Protein Sidt2.
Piao G, Fan L, Zhang Y, Jiang W, Guo X, Liu R, Wang Q, Jia S, Liang J, Li Y
International journal of nanomedicine 2025;20:7743-7762
International journal of nanomedicine 2025;20:7743-7762
Salidroside Improves Periodontitis by Mitigating Inflammatory Reactions and Enhancing Osteogenic Differentiation of Human Periodontal Ligament Stem Cells.
Li W, Liu Q, Chen S, Zhi M, Yang P, Zhang Y, Wu Z, Zhang J, Feng Q
Drug design, development and therapy 2025;19:8097-8114
Drug design, development and therapy 2025;19:8097-8114
Astragaloside IV Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells via Activating PI3K/AKT/eNOS/NO Signaling Pathway: In vitro and in vivo Study.
Song Y, Hu J, Yang P, Zhang Y, Wu Z, Chen S, Zhang J
Drug design, development and therapy 2025;19:6073-6088
Drug design, development and therapy 2025;19:6073-6088
Irisin Mitigates Doxorubicin-Induced Cardiotoxicity by Reducing Oxidative Stress and Inflammation via Modulation of the PERK-eIF2α-ATF4 Pathway.
Zhang Z, Yu X, Li J, Shen X, Fu W, Liu Y, Dong X, Wang Z
Drug design, development and therapy 2025;19:1067-1081
Drug design, development and therapy 2025;19:1067-1081
Effects of ADRM1 on osteoblast differentiation and mineralization in osteoporosis.
Zhuang H, Lin Y, Lin C, Zheng M, Yao X, Xu Y
American journal of translational research 2025;17(1):416-428
American journal of translational research 2025;17(1):416-428
Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes.
Yan J, Zhao W, Wang H, Zhou L, Li X, Wang G
Hepatic medicine : evidence and research 2025;17:141-159
Hepatic medicine : evidence and research 2025;17:141-159
2-Dodecyl-6-methoxycyclohexa-2,5-dien-1,4-dione alleviates liver fibrosis and improves intestinal flora and bile acid metabolism.
He Y, Hoa Pham TT, Xu J, Hong S, Wang J, Zhai H, Tao Q, Li R, Zhang G, Shi X
Frontiers in pharmacology 2025;16:1581138
Frontiers in pharmacology 2025;16:1581138
Dl-3-n-butylphthalide attenuates DOX-induced cardiotoxicity in mice by inhibiting Nrf2/Keap1 complex formation.
Yan Y, Fang M, Zhao C, Lin X, Tong C, Xiang C, Ran Y, Wang X, Li S, Chen G, Fu L
Frontiers in pharmacology 2025;16:1542296
Frontiers in pharmacology 2025;16:1542296
An anti-FAP-scFv-functionalized exosome-carrying hydrogel delivers SKI mRNA to fibrotic nucleus pulposus cells to alleviate intervertebral disc degeneration by regulating FOXO3.
Li Y, Zhai Y, Wang T, Wang S, Tian Y, Bian Z, Zhang Y, Zhang C, Liu M, Li C
Theranostics 2025;15(9):3877-3899
Theranostics 2025;15(9):3877-3899
Rapid cutaneous wound healing in nude mice by fetal skin-derived stem cells involves enhanced collagen secretion and angiogenesis.
Geng Y, Zhang W, Dun X, Wang Y, Shao Y
Frontiers in medicine 2025;12:1557973
Frontiers in medicine 2025;12:1557973
Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis.
Tan C, Wang J, Ye X, Kasimu K, Li Y, Luo F, Yi H, Luo Y
Frontiers in molecular biosciences 2025;12:1507163
Frontiers in molecular biosciences 2025;12:1507163
Efficacy and safety of pseudolaric acid B against Echinococcus multilocularis in vitro and in a murine infection model.
Dawa ZM, Zhai T, Liu CC, Fan HN
Frontiers in medicine 2025;12:1503472
Frontiers in medicine 2025;12:1503472
Spatial discovery of pyrotinib overcoming HER2-positive breast cancer resistance by breaking fibroblast-induced immune barriers.
Yang C, Xu Y, Lin Z, Zhang A, Li L, Ye Z, Zhang Q, Hu H, Ren G, Cheng P, Wang Z, Wang O
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Sep;82:101261
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Sep;82:101261
Dl-3-n-butylphthalide attenuates acute myocardial infarction by inhibiting the binding of Nrf2/Keap1.
Yan Y, Huang Z, Cheng L, Zhao S, Gao H, Chen K, Huang F, Mou L, Chen G, Fu L, Xu G
Toxicology and applied pharmacology 2025 Sep;502:117424
Toxicology and applied pharmacology 2025 Sep;502:117424
METTL3 Silencing Suppresses Cardiac Fibrosis Post Myocardial Infarction via m6A Modification of SMOC2.
He Y, Pan X, Liu Z, Zuo P, Sheng Z, Hao C, Tao Z, Chen Z, Song J, Ma G, Ling S
Journal of cellular and molecular medicine 2025 Sep;29(17):e70829
Journal of cellular and molecular medicine 2025 Sep;29(17):e70829
Quercetin diminishes scleral ER stress and protein misfolding: High throughput transcriptome analysis in form-deprivation myopia of Guinea pigs.
Lv L, Che D, Zhang Z, Zhang W, Zhou Q, Li F, Zhou J
Experimental eye research 2025 Sep;258:110485
Experimental eye research 2025 Sep;258:110485
miR-29a regulates scleral remodelling via TLR7/8-dependent inflammatory signalling in myopia.
Lv L, Shao Q, Zhou J, Zhu Y
Experimental eye research 2025 Sep;258:110474
Experimental eye research 2025 Sep;258:110474
Parathyroid glands exhibit reduced parenchymatic chief cells and increased extracellular collagen as a response to a long-term low-phosphorus diet in pigs.
Oster M, Reyer H, Hadlich F, Ponsuksili S, Wolf P, Wimmers K, Keiler J
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Sep;22:471-482
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Sep;22:471-482
Piezoelectric-IL-4 programmed regulation of immuno-microenvironment-induced mesenchymal stem cell recruitment and differentiation for bone regeneration.
Zhang J, Wang W, Wang M, Hai H, Li K, Wang L, Lei M, Cui L, Liu H, Guo J, Liu C
Ultrasonics sonochemistry 2025 Sep;120:107431
Ultrasonics sonochemistry 2025 Sep;120:107431
HMGB1-mediated macrophage polarization to M2 phenotype promotes ureteral stricture: therapeutic potential of HMGB1 inhibitors.
Zheng J, Tao L, Liu Y, Zhang Y, Cheng L, Hao Z
European journal of medical research 2025 Sep 29;30(1):893
European journal of medical research 2025 Sep 29;30(1):893
Mechanism of Bao Gan Ning decoction in attenuating hepatic fibrosis via modulation of the gut microbiome and PPAR/CYP7A1-mediated bile acid metabolism.
Li M, Deng K, Zheng R, Li Y, Xiang L, Cheng J, Wang Y, Kuang S, Huang S, Lv Z
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120488
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120488
Sustained Mg/Sr ion delivery from injectable silk fibroin hydrogels drives SCAP osteogenic differentiation.
Chen C, Gao Z, Li Y, Zhou T, Zheng H, Jiang S, Yang Y, Wei Y
iScience 2025 Sep 19;28(9):113353
iScience 2025 Sep 19;28(9):113353
Downregulation of HDAC9 Alleviates Autophagy Dysfunction by Inducing Acetylation of ATG4B in Metabolic Dysfunction-Associated Steatotic Liver Disease.
Ma XH, Liu GP, Liu L, Dou ZY, He X, Chen X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70991
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70991
Farrerol ameliorates diabetic cardiomyopathy by inhibiting ferroptosis via miR-29b-3p/SIRT1 signaling pathway in endothelial cells.
Guo Y, Yu XR, Gu HD, Wang YJ, Yang ZG, Chi JF, Zhang LP, Lin H
World journal of diabetes 2025 Sep 15;16(9):109553
World journal of diabetes 2025 Sep 15;16(9):109553
Oxymatrine attenuates pulmonary fibrosis via APE1‑mediated regulation of the PINK1/Parkin pathway.
Xu W, Xie T, Zhang B, Zhao J, Zhang L, Zheng Y, Ding Y
Molecular medicine reports 2025 Oct;32(4)
Molecular medicine reports 2025 Oct;32(4)
TGF-β1/IL-11 positive loop between renal tubular epithelial cell and fibroblast promotes the ectopic calcification of renal interstitial fibroblasts in rats.
Zhong J, Duan X, Yang H, Liu Z, Zhong W, Zhang Z, Huang Y, Zeng H, Zhao H, Liu Y, Liu Y, Zeng G, Zhao Z
Biochemical pharmacology 2025 Oct;240:117074
Biochemical pharmacology 2025 Oct;240:117074
Rottlerin inhibits PKCδ to attenuate pulmonary fibrosis by suppressing NLRC4/ASC-mediated pyroptosis.
Wang Y, Zhang T, Gou X, Yuan W, He S, Zhang S, Chen Z, Xu G, Wu D, Xu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157154
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157154
Icariside II attenuates renal fibrosis through mTOR signaling modulation: an integrated approach combining network pharmacology, molecular dynamics, and in vitro validation.
Ding P, Pan JC, Tian WJ, Yang YJ, Feng YH, Gao G, Wu CL, Xin ZC
Translational andrology and urology 2025 Oct 31;14(10):3159-3180
Translational andrology and urology 2025 Oct 31;14(10):3159-3180
Apelin-13 treats postmenopausal osteoporosis by reducing mitochondrial oxidative phosphorylation and modulating the OPG/RANK/RANKL/IGF-1 pathway.
Meng X, Meng D, Xiang C, Pu L, Yin X, Yang J
Biochemical and biophysical research communications 2025 Oct 30;786:152738
Biochemical and biophysical research communications 2025 Oct 30;786:152738
Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling.
Huang B, Medina P, He J, Zeng Z, Kim S, Romo J, Koppitch K, Zhang CC, Gyarmati G, Park Y, Bohovyk R, N'Guetta PY, Guo J, Ma T, Schreiber ME, Xu C, Pham J, Parvez RK, Su J, Xia MW, Liu Z, Perin L, El-Nachef D, Murry CE, Kumar S, O'Brien L, Zimmerman KA, Ichida J, Lindström NO, Pastor-Soler NM, Hallows KR, Staruschenko A, Peti-Peterdi J, Jiang C, McMahon AP, Li Z
Cell stem cell 2025 Oct 2;32(10):1614-1633.e13
Cell stem cell 2025 Oct 2;32(10):1614-1633.e13
M2-exo promote orthodontic bone remodeling via the MeCP2-TCF20-HDAC1 axis.
Chen M, Li Y, Yang Z, Chen M, Li J, Bao G, Ma L, Hu J
Stem cell research & therapy 2025 Oct 15;16(1):569
Stem cell research & therapy 2025 Oct 15;16(1):569
A hydrogel tissue adhesive incorporating basic fibroblast growth factor-loaded liposomes accelerates cutaneous wound healing by enhancing cell proliferation, collagen synthesis and angiogenesis.
Geng Y, Gao Y, Qi D, Wang Z, Zou Z, Zhang Z, Lian J, Zhang Z, He C, Shao Y
Acta biomaterialia 2025 Oct 1;205:242-259
Acta biomaterialia 2025 Oct 1;205:242-259
Injectable protein hydrogel microspheres with reactive oxygen species-responsive nitric oxide release for cardiac protection against ischemia/reperfusion injury.
Zheng H, Jia F, Gao Y, Deng K, Shen L, Zheng C, Xie X, Gao C, Ren T, Zhu Y
Acta biomaterialia 2025 Oct 1;205:176-192
Acta biomaterialia 2025 Oct 1;205:176-192
H3K18 lactylation-hexokinase 2 positive feedback loop promotes osteogenesis of ASPCs in facial infiltrating lipomatosis.
Chen H, Hua C, Chang SJ, Qiu Y, Lin X, Sun B
Stem cell research & therapy 2025 Oct 1;16(1):538
Stem cell research & therapy 2025 Oct 1;16(1):538
Comprehensive analysis of extracellular matrix remodelling via cyclophilin inhibition in human models of alcohol-related liver fibrosis.
Rastovic U, Campinoti S, Wei L, Almeida B, Bozzano SF, Amiri R, Harris N, Ajayi O, Koay TS, Kerins C, Kenny FN, Zamalloa A, Adofina L, Miquel R, Zen Y, Srinivasan P, Menon K, Heaton N, Luni C, Gentleman E, Shaw T, Ure D, Chokshi S, Urbani L, Palma E
British journal of pharmacology 2025 Nov;182(22):5647-5669
British journal of pharmacology 2025 Nov;182(22):5647-5669
Polycystin-1 Mutant Alters Mechanotransduction in Response to Collagen and Extracellular Matrix Stiffness via Daam1-Dependent Microfilament Remodeling.
Zhou J, Deng Y, Mei J, Wan M, Xue N, Zong X, Zhou J, Ding J, Yan T, Jiang Y, Xia T, Zheng P, Zhu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e09846
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e09846
From Gene to Scar: Proteome-Wide Causal Insights into Keloid Pathogenesis and Prevention.
Xu Y, Liu JC, Jiang Z, Zhang J, He R, Wan M, Zhao S
Advances in wound care 2025 Nov 5;
Advances in wound care 2025 Nov 5;
The TRPV4-YAP axis mediates cytoskeletal and extracellular matrix remodeling in trabecular meshwork cells as a novel glaucoma mechanism.
Xu J, Liu K, Wang F, Su Y
Scientific reports 2025 Nov 24;15(1):41644
Scientific reports 2025 Nov 24;15(1):41644
Curcumenol exerts anti-pulmonary fibrosis effects through modulation of the immune signature target SPP1: based on comprehensive bioinformatics and experiments validation.
Li C, Wen R, Xiong Y, Tan QW, Zhai XY, Xiong Y, Dai LS
International immunopharmacology 2025 Nov 14;165:115469
International immunopharmacology 2025 Nov 14;165:115469
SIRT1 Alleviates Oxidative Stress-Induced Mitochondrial Dysfunction and Mitochondria-Associated Membrane Dysregulation in Stress Urinary Incontinence.
Chen L, Tang J, Zuo X, Li B, Liu C, Hong S, Min J, Hu M, Li S, Zhou M, Chen M, He Y, Xiao Y, Huang X, Hong L
Cell proliferation 2025 May;58(5):e70009
Cell proliferation 2025 May;58(5):e70009
Tryptanthrin alleviate lung fibrosis via suppression of MAPK/NF-κB and TGF-β1/SMAD signaling pathways in vitro and in vivo.
Niu M, Wang YZ, Deng XM, Wu X, Hua ZY, Lv TT
Toxicology and applied pharmacology 2025 May;498:117285
Toxicology and applied pharmacology 2025 May;498:117285
LncRNA NAV2-AS2 is critical for fibroblast-to-myofibroblast transition and cardiac fibrosis.
Rong R, Yuan T, Yan Z, Tan L, Wei X, Li G, Gao H, Zhang J, Zhao X, Zhang Z, Wang M, Liu G, Xia F, Kong X, Zhu L, Cai H, Chen J, Qin W
International journal of biological macromolecules 2025 May;306(Pt 1):141400
International journal of biological macromolecules 2025 May;306(Pt 1):141400
EFNA2 Mediates Stiffness-Regulated Hypopharyngeal Cancer Progression.
Hu S, Liu Y, Cheng M, Xu M, Liu H, Shan Y, Ni H, Xia T, Zhang Q, Zhang Z, You B
Clinical and experimental otorhinolaryngology 2025 May;18(2):188-199
Clinical and experimental otorhinolaryngology 2025 May;18(2):188-199
Engineering Antibacterial, Biocompatible, Anti-Oxidant Titanium-Based Implants Using Polyphenols-Chlorhexidine Networks for Bone Regeneration.
Wang Y, Hong B, Yin B, Li Y, Huang L, Tan S, Gao T, Maitz MF, Zhang J, Zheng S, Huang C, Qiu H, Chen J, Li X
Advanced healthcare materials 2025 May;14(14):e2404958
Advanced healthcare materials 2025 May;14(14):e2404958
TiO(2) Nanotube Implants Modified with Silk Fibroin and Mesoporous Silica Nanocomposite Coatings Enable Efficient Drug Release to Promote Osteogenesis.
Mu Y, Li M, Zhao X, Gong C, Luo Z, Li B, Zhang W, Ge X, Chen S, Zhou J
ACS applied materials & interfaces 2025 May 28;17(21):30600-30612
ACS applied materials & interfaces 2025 May 28;17(21):30600-30612
Loading tea polyphenols enhances the repair of human umbilical cord mesenchymal stem cell sheet after spinal cord injury.
Zhao Y, Ye C, Wang H, Chen C, Lu Y, Yang C, Xu T, Zhou Y, Wu Z, Song X, Zhu Z, Yang Z, Chen X
Stem cell research & therapy 2025 May 28;16(1):264
Stem cell research & therapy 2025 May 28;16(1):264
Hypoxia-inducible factor-1 alpha (HIF-1α) inhibitor AMSP-30 m attenuates CCl(4)-induced liver fibrosis in mice by inhibiting the sonic hedgehog pathway.
Lu L, Ma Y, Tao Q, Xie J, Liu X, Wu Y, Zhang Y, Xie X, Liu M, Jin Y
Chemico-biological interactions 2025 May 25;413:111480
Chemico-biological interactions 2025 May 25;413:111480
Mechanoregulative hydrogel facilitates rapid scarless healing by self-adaptive control of wound niche at different stages.
Shu H, Zhang T, Jiang Y, Diao Z, Xu Y, Long J, Chen T, Zhang M, Zhang Z, Chen J, Huang S, Zhang L
Science advances 2025 May 23;11(21):eadv9895
Science advances 2025 May 23;11(21):eadv9895
Asb10 accelerates pathological cardiac remodeling by stabilizing HSP70.
Lin K, Wei W, Chen S, Gong Y, Wang X, Wang M, Li R, Zhao Y, Xu S, Jin C, Jiang C, Fu G, Li Q
Cell death & disease 2025 May 22;16(1):409
Cell death & disease 2025 May 22;16(1):409
Temporal Proteome Profiling of Anterior Cruciate Ligament Tear Remnants: Secretory Proteins in the Acute Phase Potentially Promote Tissue Repair.
Liu Y, Li B, Zhang J, Zhao B, Chen L, Chen B
Journal of proteome research 2025 May 2;24(5):2302-2313
Journal of proteome research 2025 May 2;24(5):2302-2313
Tetrathiomolybdate alleviates bleomycin-induced pulmonary fibrosis by reducing copper concentration and suppressing EMT.
Wang Y, Chen S, Zhou Z, Jiang J, Chen S
European journal of medical research 2025 May 19;30(1):394
European journal of medical research 2025 May 19;30(1):394
Urolithin A enhances diabetic wound healing: Insights from parkin-mediated mitophagy in endothelial progenitor cells.
Fang X, Shao Z, Ding H, Xu H, Tu Z, Wang H, Li D, Huang C, Jiang C
International immunopharmacology 2025 May 16;155:114572
International immunopharmacology 2025 May 16;155:114572
Aggressive characteristics of tumor deposits in colorectal cancer highlight the need for staging refinement in patients with 0-3 metastatic lymph nodes.
Hu X, Xie S, Yang Z, Zhao X, Gong L, Yang P, Yang L, Wang S, Bao G, He X
International journal of cancer 2025 May 1;156(9):1826-1839
International journal of cancer 2025 May 1;156(9):1826-1839
LINC00525 promotes cell proliferation and collagen expression through feedforward regulation of TGF-β signaling in hypertrophic scar fibroblasts.
Chen L, Yin Y, Li J, Li Q, Zhu Z, Li J
Burns : journal of the International Society for Burn Injuries 2025 Mar;51(2):107353
Burns : journal of the International Society for Burn Injuries 2025 Mar;51(2):107353
Ergothioneine Ameliorates Liver Fibrosis by Inhibiting Glycerophospholipids Metabolism and TGF-β/Smads Signaling Pathway: Based on Metabonomics and Network Pharmacology.
Mao Y, Xie Z, Zhang X, Fu Y, Yu X, Deng L, Zhang X, Hou B, Wang X, Ma M, Ren F
Journal of applied toxicology : JAT 2025 Mar;45(3):514-530
Journal of applied toxicology : JAT 2025 Mar;45(3):514-530
Sacubitril/valsartan attenuates inflammation and myocardial fibrosis in Takotsubo-like cardiomyopathy.
Kuang J, Jia Z, Chong TK, Chen J, Liu K, Wang X, Li Z, Zhang J, Kong Y, Deng L, Cadieras M, Sun Y, Sun R, Lu Q, Liu Y
Journal of molecular and cellular cardiology 2025 Mar;200:24-39
Journal of molecular and cellular cardiology 2025 Mar;200:24-39
VHL ameliorates arecoline-induced oral submucosal fibrosis by promoting HDAC6 ubiquitination and blocking NF-κB pathway.
Sun H, Yang C, Yin X, Chen S, Huang Y, Kuang H, Luo W
Scientific reports 2025 Mar 4;15(1):7563
Scientific reports 2025 Mar 4;15(1):7563
Establishment and characterization of a novel immortalized human aortic valve interstitial cell line.
Wang Z, Rao Z, Wang Y, Dong N
Scientific reports 2025 Mar 29;15(1):10917
Scientific reports 2025 Mar 29;15(1):10917
Cyanidin-3-glucoside upregulated NDRG2 through the PI3K/AKT pathway to alleviate EMT and ECM in renal fibrosis.
Lu Q, Liu J, Xiong Y, Jian J, Wang J, Chen Z, Wan S, Liu X, Wang L
Scientific reports 2025 Mar 28;15(1):10695
Scientific reports 2025 Mar 28;15(1):10695
Triptolide combined with salvianolic acid B alleviates CCL(4)-induced liver fibrosis by suppressing the Th17/IL-17A axis.
Jiang S, Jiang Y, Feng J, Hou J, Qin Z, Wang Y, Yang K, Li J
International immunopharmacology 2025 Mar 26;150:114300
International immunopharmacology 2025 Mar 26;150:114300
Dietary phytosterol supplementation mitigates renal fibrosis via activating mitophagy and modulating the gut microbiota.
Yang F, Gao Y, Xie S, Yang W, Wang Q, Ye W, Sun L, Zhou J, Feng X
Food & function 2025 Mar 17;16(6):2316-2334
Food & function 2025 Mar 17;16(6):2316-2334
Neddylation of RhoA impairs its protein degradation and promotes renal interstitial fibrosis progression in diabetic nephropathy.
Li XQ, Jin B, Liu SX, Zhu Y, Li N, Zhang QY, Wan C, Feng Y, Xing YX, Ma KL, Liu J, Jiang CM, Lu J
Acta pharmacologica Sinica 2025 Jun;46(6):1692-1705
Acta pharmacologica Sinica 2025 Jun;46(6):1692-1705
Expression, optimization and biological activity analysis of recombinant type XII collagen in Pichia pastoris.
Gao Q, Zhang Z, Fu R, Zhu C, Yuwen W, Xu R, Duan Z, Fan D
International journal of biological macromolecules 2025 Jun;311(Pt 4):143720
International journal of biological macromolecules 2025 Jun;311(Pt 4):143720
P4HB, a novel succinated protein, is essential for fumarate-induced cancer metastasis.
Song X, Rao H, Huang C, Huang M, Ma Y, Xin J, Hou J, Hu Z, He L, Pan F, Yang L, Guo Z
International journal of biological macromolecules 2025 Jun;311(Pt 3):143885
International journal of biological macromolecules 2025 Jun;311(Pt 3):143885
Single-cell transcriptomics reveal the effects of chemoimmunotherapy on hypopharyngeal cancer and its tumor microenvironment.
Zhu X, Xu H, Zhao Y, Diao W, Yan F, Zhu Y, Zhao T, Chen X
Oral oncology 2025 Jun;165:107347
Oral oncology 2025 Jun;165:107347
Mast cell tryptase-PAR2 axis promotes ovarian fibrosis through RNF152-mediated stabilization of Bcl-xL.
Zhang X, Zhang J, Wang C
Journal of ovarian research 2025 Jun 5;18(1):122
Journal of ovarian research 2025 Jun 5;18(1):122
Construction and validation of a prognostic nomogram model integrating machine learning-pathomics and clinical features in IDH-wildtype glioblastoma.
Li Y, Ouyang P, Zheng Z, Deng J, Guo A, Wang W, Liu Y, Peng Y, Liao Y, Wang X, Wang H, Wang Z, Mo Z, Weng J, Xv H, Zheng X, Liu J, Wang Y, Cao Y, Huang G, Zhang X, Qi S
Journal of translational medicine 2025 Jun 3;23(1):618
Journal of translational medicine 2025 Jun 3;23(1):618
FKBP5 promotes osteogenic differentiation of mesenchymal stem cells through type-I interferon pathway Inhibition.
Tang J, Li M, Chen Y, Liang Y, Yan W, Ning Q, Deng H, Liu H, Li Y, Huang L
Cellular and molecular life sciences : CMLS 2025 Jun 14;82(1):236
Cellular and molecular life sciences : CMLS 2025 Jun 14;82(1):236
The KSR1/MEK/ERK signaling pathway promotes the progression of intrauterine adhesions.
Wu S, Chen Q, Yang X, Zhang L, Huang X, Huang J, Wu J, Sun C, Zhang W, Wang J
Cellular signalling 2025 Jul;131:111730
Cellular signalling 2025 Jul;131:111730
Tβ4-Engineered ADSC Extracellular Vesicles Rescue Cell Senescence Through Separable Microneedle Patches for Diabetic Wound Healing.
Ding Y, Wang J, Li J, Cheng Y, Zhou S, Zhang Y, Zhao Y, Zhou M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(26):e2505009
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(26):e2505009
FABP4 Inhibitor Improves Right Ventricular Fibrosis in Metabolic Syndrome- Related Pulmonary Hypertension due to Left Heart Disease in Mice.
Qiu H, Chen W, Chen J, Jun L, Chen Y, Tan Y, Wang T, Li J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70833
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70833
Mechanistic exploration of Dahuang Zhechong Pill against hepatic fibrosis via integrated serum pharmacochemistry, UHPLC-ESI-QTOF-MS/MS, network pharmacology, and molecular docking with cellular and zebrafish validation.
Li M, Deng K, Li Y, Xiang L, Wang Y, Shi H, Kuang S, Wen J, Zhou C, Lv Z, Huang S
Journal of ethnopharmacology 2025 Jul 24;351:120102
Journal of ethnopharmacology 2025 Jul 24;351:120102
Ameliorating Myocardial Infarction by Concurrent Pyroptosis Suppression and On-Demand Oxygen Production via Functionalized Nanocarrier.
Zhu W, Lu Y, Zong B, Chen Z, Ma Y, Wang H, Cao P, Han B
ACS applied materials & interfaces 2025 Jul 23;17(29):41626-41636
ACS applied materials & interfaces 2025 Jul 23;17(29):41626-41636
Pannexin1 via P2rx7/amphiregulin contributes to cardiac fibrosis post myocardial infarction.
Deng N, You L, Guo H, Wei Y, Xu F, Chen D, Luo S, Huang S, Zuo S, Li W, Si X
Journal of molecular histology 2025 Jul 15;56(4):230
Journal of molecular histology 2025 Jul 15;56(4):230
Timosaponin AIII alleviates type 2 diabetes-induced cardiomyopathy by targeting galectin-3 (LGALS3).
Yin J, Yu C, Zhang Z, Cong J
Experimental cell research 2025 Jul 15;450(2):114665
Experimental cell research 2025 Jul 15;450(2):114665
Secreted phosphoprotein 1 promotes the activation of keloid fibroblasts via the CD44/TGF-β1/Smad pathway.
Tu Y, Xiong Y, Liu O, Peng Y
Experimental cell research 2025 Jul 15;450(2):114658
Experimental cell research 2025 Jul 15;450(2):114658
Transcriptional and post-translational mechanisms of ECM remodeling in rotator cuff tendons under hyperlipidemic conditions.
Rajalekshmi R, Agrawal DK
Life sciences 2025 Jul 1;372:123647
Life sciences 2025 Jul 1;372:123647
Construction of a prostate adenocarcinoma molecular classification: integrating spatial transcriptomics with retrospective cohort validation.
Lu B, Liu Y, Ji G, Yao Y, Yang Z, Zhu B, Wang L, Dong K, Li Y, Shi J, He J, Huang R, Zhou W, Cui X, Pan X, Cui X
Journal of translational medicine 2025 Jul 1;23(1):717
Journal of translational medicine 2025 Jul 1;23(1):717
Improving tendon repair through spatiotemporal modulation of TGF-β1 expression using an ultrasound-responsive hydrogel carrying siRNA-loaded nanoparticles.
Liu C, Sun J, Tan Y, Yu Shi J, Hong AZ, Ju F, Chen QZ, Zhang C, Li J, Zhang L, Yang QQ, Zhou YL
Acta biomaterialia 2025 Jul 1;201:485-500
Acta biomaterialia 2025 Jul 1;201:485-500
Extracellular vesicle-derived lncRNA VIM-AS1 promotes diabetic wound healing by promoting glycolysis and alleviating cellular senescence.
Liang F, Huang N, Tian Y, Fang Y, Huang C, Qiu B, Lu T, Zheng L, Cheng J, Zhu B, Zhao J
Stem cell research & therapy 2025 Jul 1;16(1):341
Stem cell research & therapy 2025 Jul 1;16(1):341
Excessive accumulation of thioredoxin promotes osteogenic differentiation of mesenchymal stem cells of ligament in ankylosing spondylitis by upregulating autophagy levels.
Qiao J, Zhou B, Han C, Xu Q, Feng X, Xu W
Biochemical and biophysical research communications 2025 Jan;745:151255
Biochemical and biophysical research communications 2025 Jan;745:151255
N6-methyladenosine modification of SPOP relieves ferroptosis and diabetic cardiomyopathy by enhancing ubiquitination of VDAC3.
Meng W, Li L
Free radical biology & medicine 2025 Jan;226:216-229
Free radical biology & medicine 2025 Jan;226:216-229
Short-term exposure to low doses of aflatoxin B1 aggravates nonalcoholic steatohepatitis by TLR4-mediated necroptosis.
Zeng J, Chen L, Tang J, Xue J, Wang Q, Feng X, Chen X, Huang K, Gan F
Free radical biology & medicine 2025 Jan;226:129-142
Free radical biology & medicine 2025 Jan;226:129-142
GDF15 promotes osteogenic differentiation of human dental pulp stem cells by activating the TGF-β/SMAD signaling pathway.
Deng P, Yang B, Huang C, Li Y, Mei Z, Li Y, Li J
Journal of tissue engineering 2025 Jan-Dec;16:20417314251357752
Journal of tissue engineering 2025 Jan-Dec;16:20417314251357752
Supplementation with carnosine, a food-derived bioactive dipeptide, alleviates dexamethasone-induced oxidative stress and bone impairment via the NRF2 signaling pathway.
Li XY, Gu XY, Li XM, Yan JG, Mao XL, Yu Q, Du YL, Kurihara H, Yan CY, Li WX
Journal of the science of food and agriculture 2025 Jan 30;105(2):1091-1104
Journal of the science of food and agriculture 2025 Jan 30;105(2):1091-1104
Atractylenolide-III restrains cardiac fibrosis after myocardial infarction via suppression of the RhoA/ROCK1 and ERK1/2 pathway.
Li X, Zhu X, Jiang S, Yang W, Zhang F, Guo X, Wei Y
International immunopharmacology 2025 Jan 3;145:113825
International immunopharmacology 2025 Jan 3;145:113825
A new mechanism of arterial calcification in diabetes: interaction between H3K18 lactylation and CHI3L1.
Zhu Y, Chen JC, Zhang JL, Wang FF, Liu RP
Clinical science (London, England : 1979) 2025 Jan 29;139(2):115-130
Clinical science (London, England : 1979) 2025 Jan 29;139(2):115-130
Extracellular vesicles from adipose-derived stem cell alleviate diabetic cardiomyopathy by regulating Chit1/NLRP3/Caspase-1-Mediated pyroptosis.
Zhang Y, Zhang L, Li P, Qiu L, Qu Y, Wu Y, Song H
International immunopharmacology 2025 Jan 27;146:113860
International immunopharmacology 2025 Jan 27;146:113860
Hydrogen sulfide attenuates disturbed flow-induced vascular remodeling by inhibiting LDHB-mediated autophagic flux.
Wang X, Huang X, Zhang Y, Huo H, Zhou G, Shen L, Li L, He B
Redox biology 2025 Feb;79:103456
Redox biology 2025 Feb;79:103456
Integrating Network Pharmacology and In Vitro Experimental Verification Revealing Bushenhuoxue Recipe Against Intrauterine Adhesions via PI3K-AKT Signaling Pathway.
Wang L, Zhuang L, Lu Y, Jia J, Chen C, Zhang Y, Hong Z, Wang X
Biochemical genetics 2025 Feb;63(1):686-697
Biochemical genetics 2025 Feb;63(1):686-697
Integrated UHPLC-Q-exactive orbitrap HRMS and serum pharmacochemistry for the investigation of anti-hepatic fibrosis effect of Baoganning Decoction.
Deng K, Li M, Xiang L, Wang Y, Li Y, Wen J, Li Y, Kuang S, Wen J, Zhou C, Huang S, Lv Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156363
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156363
Cancer-secreted exosomal miR-1246 promotes colorectal cancer liver metastasis by activating hepatic stellate cells.
Liu X, Liu J, Wang X, Zou Y, Tao X, Li J, Ye M, Xu W, Deng Y, Liu L, Sun J, Zhang Q
Molecular medicine (Cambridge, Mass.) 2025 Feb 20;31(1):68
Molecular medicine (Cambridge, Mass.) 2025 Feb 20;31(1):68
Astaxanthin Prevents Glucocorticoid-Induced Femoral Head Osteonecrosis by Targeting Ferroptosis through the JAK2/STAT3 Signaling Pathway.
Lin YZ, Chen ZH, Yang JF, Han LJ, Yu YT, Zhan JN, Tan GC, Liu LY, Xie CL, Shan P, Jin C, Liu HX
Journal of agricultural and food chemistry 2025 Feb 19;73(7):4270-4287
Journal of agricultural and food chemistry 2025 Feb 19;73(7):4270-4287
Role of SAA1 in Endometrial Extracellular Matrix Remodeling in Polycystic Ovary Syndrome: Implication for Pregnancy Loss.
Zhu Q, Wang Y, Xu L, Shi M, Meng Y, Shao C, Lu Y, He Y, Huang J, Li X, Li B, Long Y, Ding Y, Qi J, Wang W, Du Y, Sun Y
The Journal of clinical endocrinology and metabolism 2025 Feb 18;110(3):658-667
The Journal of clinical endocrinology and metabolism 2025 Feb 18;110(3):658-667
WNT inhibitor SP5-mediated SERPING1 suppresses lung adenocarcinoma progression via TSC2/mTOR pathway.
Shen Y, Dong X, Li X, Shi Z, Shao T, Jiang J, Song J
Cell death & disease 2025 Feb 17;16(1):103
Cell death & disease 2025 Feb 17;16(1):103
SCGB1D4 downregulation links to fibrosis in intrauterine adhesion patients and rat models†.
Zhao J, Wang Y, Ma C, Feng Y, Wang Y, Sun S
Biology of reproduction 2025 Feb 14;112(2):273-285
Biology of reproduction 2025 Feb 14;112(2):273-285
PAI-1 deficiency inhibits endometrial fibrosis via modulation of the FAK/Src/ERK and AKT signalling pathways.
Zhao H, Wang X, Liu J, Yu M, Bao H
Reproductive biomedicine online 2025 Dec;51(6):105120
Reproductive biomedicine online 2025 Dec;51(6):105120
EXO/hydrogel system for sequential regulation of endogenous hyaline cartilage regeneration.
Wu K, Gong R, Gao T, Hu Y, Wang H, Zhang W, Wang X, Wang Y, Zhang N
Materials today. Bio 2025 Dec;35:102598
Materials today. Bio 2025 Dec;35:102598
Whitlockite-loaded silk fibroin/polyvinyl alcohol hydrogel composited with porous tantalum scaffold enhances bone regeneration and immunomodulation via the TGF-β/NRROS signaling pathway.
Ge B, Jiao H, Xu J, Wu D, Xie Q, Zheng G, Cao F, Yin G, Zhao D, Li J
Materials today. Bio 2025 Dec;35:102532
Materials today. Bio 2025 Dec;35:102532
Sappanone A, a potential natural inhibitor of PI3K, alleviates metabolic dysfunction-associated steatohepatitis in experimental models.
Qiao X, Li Q, Fan R, Cheng Y, Zeng Q, Xue H, Zhang X, Zhang Y, Liu Y
Biochemical pharmacology 2025 Dec;242(Pt 3):117305
Biochemical pharmacology 2025 Dec;242(Pt 3):117305
COL4A2 drives ECM remodeling and stiffness increasing to promote breast cancer metastasis via YAP signaling pathway in dECM induced models.
Peng J, Zhu W, Zhang C, Yin S, Ye J, Mao H, Li M, Zhao J
Biomaterials advances 2025 Dec;177:214430
Biomaterials advances 2025 Dec;177:214430
Heterogeneity of active mast cells, endothelial cells, and fibroblasts in hemophilic arthritis defined by synovial single-cell sequencing.
Lin K, Fan S, Yang X, Hou W, Zhang J, Liao J, Han L, Peng P, Xiao F, Fang W, He X, Tian J, Lu S, Yang F, Wei Q, He M
Scientific reports 2025 Dec 8;15(1):43350
Scientific reports 2025 Dec 8;15(1):43350
Lumican from DESC spheroids enhances odontoblastic differentiation of SCAPs.
Zhang Q, Huang S, Liu X, Zhang M, Sun J, Liu M, Nie H, Lei L
Stem cell research & therapy 2025 Dec 7;17(1):27
Stem cell research & therapy 2025 Dec 7;17(1):27
The NAWG combinatorial strategy activates MAPK signaling to restore extracellular matrix architecture in aging skin.
Zhang M, Pan L, Ren T, Du X, Mu Y, Liu S, Bao Y, Ma L, Luo J, Li F, Zheng F, Cao S, Yue H
Medicine 2025 Dec 5;104(49):e46335
Medicine 2025 Dec 5;104(49):e46335
Serum response factor targets Cyr61 to facilitate chronic progression after ischemic acute kidney injury through renal tubular epithelial-myofibroblast transdifferentiation.
Che L, Xu L, Li C, Guan C, Bu Q, Luo C, Luan H, Zhou B, Yang C, Man X, Zhang H, Xu Y, Zhao L
European journal of medical research 2025 Dec 24;31(1):148
European journal of medical research 2025 Dec 24;31(1):148
Interleukin-27 is a multitarget regulator of fibroblast remodeling in thyroid-associated ophthalmopathy.
Zhang P, Wang X, Lu N, Nie Y, Zhang X, Liu L
iScience 2025 Dec 19;28(12):113982
iScience 2025 Dec 19;28(12):113982
Multi-omics factor analysis identifies the Tensin 1-Fermitin family homologue 2-Fibronectin 1-Integrin signaling axis as a prognostic determinant in colorectal cancer.
Chen T, Yang Y, Shi J, Dong F, Xie L, Shan Y, Wang X
Molecular biomedicine 2025 Dec 17;6(1):141
Molecular biomedicine 2025 Dec 17;6(1):141
Decreased scleral Wnt5a(hi) fibroblasts exacerbate myopia progression by disrupting extracellular matrix homeostasis in mice.
Zhu H, Chen W, Ling X, Jiao S, Yu L, Liu H, Ding M, Zhang F, Zhou Y, Pan Y, Zhou Z, Qu J, Zhao F, Zhao F, Zhou X
Nature communications 2025 Dec 16;17(1):554
Nature communications 2025 Dec 16;17(1):554
Nucleosome assembly protein-like 1 degradation-dependent novel cardioprotection mechanism of Wnt2 against ischemia‒reperfusion injury.
Wang Y, Chen L, Lin J, Liu X, Jin K, Huang C, Wang H, Jia J, Wu J, Ding Z, Gao P, Ge J, Gong H, Zou Y
Signal transduction and targeted therapy 2025 Dec 16;10(1):403
Signal transduction and targeted therapy 2025 Dec 16;10(1):403
Improving the Culture of Human Skin Explants for Use in Preclinical Testing of Wound Healing Treatments.
Guo X, Hüging M, Mirastschijski U, Blume-Peytavi U, Vogt A, Schaudinn C, Rancan F
Pharmaceutics 2025 Dec 15;17(12)
Pharmaceutics 2025 Dec 15;17(12)
Procyanidin B2 mitigate asthmatic airway remodeling by inhibiting TGF-β1-induced airway smooth muscle proliferation through ROS signaling.
Liang W, Zhang M, Wang H, Feng L, Li D, Hao R, Xie W, Zeng X, Ma Y
Tissue & cell 2025 Aug;95:102863
Tissue & cell 2025 Aug;95:102863
Loss of Trim31 Worsens Cardiac Remodeling in a Mouse Model of Heart Failure by Enhancing the Activation of the NLRP3 Inflammasome.
Duan F, Li H, Lu B, Wang X, Xu X
Inflammation 2025 Aug;48(4):2650-2662
Inflammation 2025 Aug;48(4):2650-2662
Kaempferol Remodels Liver Monocyte Populations and Treats Hepatic Fibrosis in Mice by Modulating Intestinal Flora and Metabolic Reprogramming.
Zhu Z, Zhu Z, Shi Z, Wang C, Chen F
Inflammation 2025 Aug;48(4):2198-2216
Inflammation 2025 Aug;48(4):2198-2216
Dissolvable microneedle-assisted transdermal administration of diacerein nanoparticles achieved satisfactory therapeutic effects in tendon-bone insertion repair by reducing oxidative stress and inflammation.
Sun J, Chen QZ, Hong AZ, Ju F, Wang HL, Zhang B, Liu W, Sun YC, Tan J, Yang QQ, Zhou YL
Materials today. Bio 2025 Aug;33:101999
Materials today. Bio 2025 Aug;33:101999
From stem cells to skin: ADSCP6 peptide's role in transforming scar therapy.
Li J, Zeng S, Zhou B, Yan Q, Sun Y, Chen L, Zhang E, Li J
Biochemical pharmacology 2025 Aug;238:116980
Biochemical pharmacology 2025 Aug;238:116980
Platelet-rich plasma-derived exosomes have the novel ability to alleviate insertional Achilles tendinopathy by promoting tenogenesis in tendon stem/progenitor cells.
Zhang AY, Xie QZ, Guo SZ, Liu X, Yu YH, Tang H, Yao H, Guo L, Xu SB, Bian XT, Tao X
Biomaterials advances 2025 Aug;173:214272
Biomaterials advances 2025 Aug;173:214272
Tissue-specific composite hydrogel-loaded BMSCs inhibit apoptosis and promote meniscal repair.
Meng J, Deng L, Lu J, Jiang C, Wang H, Yao J
Biomaterials advances 2025 Aug;173:214258
Biomaterials advances 2025 Aug;173:214258
Zn-Based Multi-Active Framework Nanoparticles TSA-CAN-Zn Inhibit Skin Glycation via Dual Blockade of HMGB1/RAGE and AGEs/RAGE Pathways.
Yao C, Wang H, Han J, Yang K, Lin T, Jin J, Zhu C, Liu H
Advanced healthcare materials 2025 Aug;14(21):e2500664
Advanced healthcare materials 2025 Aug;14(21):e2500664
F-box only protein 10 protects against kidney tubulointerstitial fibrosis by inhibiting ACSL4-mediated lipid peroxidation and ferroptosis.
Hu J, Ma F, Chen X, Lu X, Lu Y, Jiang Y
Cellular signalling 2025 Aug;132:111841
Cellular signalling 2025 Aug;132:111841
Folic acid-functionalized PLGA nanomedicines encapsulating echinacoside for liver cancer therapy.
Han Y, Fan J, Xia W, Dong X, Ye Y
Biochemical and biophysical research communications 2025 Aug 8;774:152049
Biochemical and biophysical research communications 2025 Aug 8;774:152049
Lymph nodes molecular subtypes unravel lymph nodes heterogeneity and clinical implications in colorectal cancer.
Guan X, Zhang Y, Sun R, Wang G, Bi X, Zhang Z, Zan L, Meng Y, Liu Y, Guo J, Ma J, Li J, Hu H, Zhang Y, Zhang X, Liu M, Jiang B, Liu H, Zou S, Xi Y, Zhou H, Bai W, Wu D, Wang X
Nature communications 2025 Aug 22;16(1):7834
Nature communications 2025 Aug 22;16(1):7834
HAS1(high) cancer associated fibroblasts located at the tumor invasion front zone promote oral squamous cell carcinoma invasion via ECM remodeling.
Jin W, Yu Q, Yu L, Zhou T, Wang X, Lu W, Zhang X, Ding L, Hu Q, Ni Y
Journal of experimental & clinical cancer research : CR 2025 Aug 14;44(1):238
Journal of experimental & clinical cancer research : CR 2025 Aug 14;44(1):238
Snhg18 regulates Yap subcellular localization to maintain bone homeostasis.
Huang J, Weng Y, Feng Y, Wu D, Chen Y, Li Z, Jiang X, Wang H, Wang Z
Nature communications 2025 Aug 14;16(1):7543
Nature communications 2025 Aug 14;16(1):7543
Irisolidone enhances osteoblast differentiation via the AMPK-ULK1-autophagy Axis to accelerate osteoporotic fracture repair.
Lao Z, Liu Z, Ji W, Chen X, Yang W, Qian Y
Biochemical pharmacology 2025 Aug 13;242(Pt 1):117234
Biochemical pharmacology 2025 Aug 13;242(Pt 1):117234
Mesenteric adipose-derived exosomal TINAGL1 enhances intestinal fibrosis in Crohn's Disease via SMAD4.
Chen Y, Li J, Zhang X, Li S, Cheng Y, Fu X, Li J, Zhu L
Journal of advanced research 2025 Apr;70:139-158
Journal of advanced research 2025 Apr;70:139-158
Laboratory investigation of METTL7A driving MSC osteogenic differentiation through YAP1 translation enhancement via eIF4F recruitment.
Cui L, Mai Z, Lu Y, Zheng J, Lin P, Chen X, Zheng Y, Lin Y, Guo B, Zhao X
International endodontic journal 2025 Apr;58(4):587-603
International endodontic journal 2025 Apr;58(4):587-603
Copper doped bioactive glass promotes matrix vesicles-mediated biomineralization via osteoblast mitophagy and mitochondrial dynamics during bone regeneration.
Ling Z, Ge X, Jin C, Song Z, Zhang H, Fu Y, Zheng K, Xu R, Jiang H
Bioactive materials 2025 Apr;46:195-212
Bioactive materials 2025 Apr;46:195-212
GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy.
Du L, Liu S, Lu Y, Ren D, Yu X, Hu Y, Yang T, Yang Q, Ming J, Zhang J, Yin X, Lu Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2407462
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2407462
Fibroblast derived C3 promotes the progression of experimental periodontitis through macrophage M1 polarization and osteoclast differentiation.
Ren F, Zheng S, Luo H, Yu X, Li X, Song S, Bu W, Sun H
International journal of oral science 2025 Apr 17;17(1):30
International journal of oral science 2025 Apr 17;17(1):30
Aging and autophagic phenotypic changes in bone marrow mesenchymal stem cells in glucocorticoid-induced osteonecrosis.
Cao R, Li H, Liu G, Yan P, Zhang J, Chen Y, Duan X, Zhao Y, Lei Y, Liu C, Guan H, Xing F, Li Y, Wang K, Kong N, Tian R, Yang P
International immunopharmacology 2025 Apr 16;152:114389
International immunopharmacology 2025 Apr 16;152:114389
Fabrication of 3D Biomimetic Smooth Muscle Using Magnetic Induction and Bioprinting for Tissue Regeneration.
Luo Y, Hu Z, Ni R, Xu R, Zhao J, Feng P, Zhu T, Chen Y, Yao J, Yao Y, Yang L, Zhang H, Zhu Y
Biomaterials research 2024;28:0076
Biomaterials research 2024;28:0076
Amlexanox Enforces Osteogenic Differentiation and Bone Homeostasis Through Inhibiting Ubiquitin-Dependent Degradation of β-Catenin.
He Q, Liu Z, Xia X, Zeng J, Liu Y, Xun J, Liu M, Mei Y, Dai R
International journal of biological sciences 2024;20(13):5254-5271
International journal of biological sciences 2024;20(13):5254-5271
Col1A1 as a new decoder of clinical features and immune microenvironment in ovarian cancer.
Xiao X, Long F, Yu S, Wu W, Nie D, Ren X, Li W, Wang X, Yu L, Wang P, Wang G
Frontiers in immunology 2024;15:1496090
Frontiers in immunology 2024;15:1496090
Fibroblasts facilitate lymphatic vessel formation in transplanted heart.
Gong H, Wang T, Sun X, Zhang Y, Qiu Y, Sun W, Zhang Y, Teng P, Hu Y, Hu X, Ma L, Xu Q, Zhao H
Theranostics 2024;14(5):1886-1908
Theranostics 2024;14(5):1886-1908
HIF2A mediates lineage transition to aggressive phenotype of cancer-associated fibroblasts in lung cancer brain metastasis.
You M, Fu M, Shen Z, Feng Y, Zhang L, Zhu X, Zhuang Z, Mao Y, Hua W
Oncoimmunology 2024;13(1):2356942
Oncoimmunology 2024;13(1):2356942
Role of integrin β1 and tenascin C mediate TGF-SMAD2/3 signaling in chondrogenic differentiation of BMSCs induced by type I collagen hydrogel.
Huang Y, Sun M, Lu Z, Zhong Q, Tan M, Wei Q, Zheng L
Regenerative biomaterials 2024;11:rbae017
Regenerative biomaterials 2024;11:rbae017
Unraveling the role of MiR-181 in skin fibrosis pathogenesis by targeting NUDT21.
Mills TW, Wu M, Alonso J, Puente H, Charles J, Chen Z, Yoo SH, Mayes MD, Assassi S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Sep;38(17):e70022
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Sep;38(17):e70022
Cyy-272, an indazole derivative, effectively mitigates obese cardiomyopathy as a JNK inhibitor.
Liu X, Cheng LT, Ye QR, Gao HC, Zhu JW, Zhao K, Liu HM, Wang YJ, Alinejad T, Zhang XH, Chen GZ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117172
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117172
Let‑7f‑5p Regulated by Hsa_circ_0000437 Ameliorates Bleomycin-Induced Skin Fibrosis.
Liu B, Li C, Bo Y, Tian G, Yang L, Si J, Zhang L, Yan Y
Journal of cellular biochemistry 2024 Sep;125(9):e30629
Journal of cellular biochemistry 2024 Sep;125(9):e30629
Angiotensin receptor blocker attacks armored and cold tumors and boosts immune checkpoint blockade.
Mei J, Chu J, Yang K, Luo Z, Yang J, Xu J, Li Q, Zhang Y, Zhang Q, Wan M, Xue N, Ding J, Zhu Y, Cai Y, Yin Y
Journal for immunotherapy of cancer 2024 Sep 6;12(9)
Journal for immunotherapy of cancer 2024 Sep 6;12(9)
Salidroside alleviates simulated microgravity-induced bone loss by activating the Nrf2/HO-1 pathway.
Wang N, Zuo Z, Meng T, Liu Y, Zheng X, Ma Y
Journal of orthopaedic surgery and research 2024 Sep 2;19(1):531
Journal of orthopaedic surgery and research 2024 Sep 2;19(1):531
NBQX mediates ventricular fibrillation susceptibility in rat models of anxiety via the Nrf2/HO-1 pathway.
Hu Y, Qu C, Zou Y, Liu X, Zhang C, Yang B
Heliyon 2024 Sep 15;10(17):e37358
Heliyon 2024 Sep 15;10(17):e37358
Chitosan/cellulose nanocrystals/graphene oxide scaffolds as a potential pH-responsive wound dressing: Tuning physico-chemical, pro-regenerative and antimicrobial properties.
Dacrory S, D'Amora U, Longo A, Hasanin MS, Soriente A, Fasolino I, Kamel S, Al-Shemy MT, Ambrosio L, Scialla S
International journal of biological macromolecules 2024 Oct;278(Pt 1):134643
International journal of biological macromolecules 2024 Oct;278(Pt 1):134643
Protective effect and mechanism of lycium barbarum polysaccharide against UVB-induced skin photoaging.
Fan L, Luan X, Jia Y, Ma L, Wang Z, Yang Y, Chen Q, Cui X, Luo D
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2024 Oct;23(10):1931-1943
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2024 Oct;23(10):1931-1943
Nuclear receptor 4A1 ameliorates renal fibrosis by inhibiting vascular endothelial growth factor A induced angiogenesis in UUO rats.
Wang H, Fang F, Zhang M, Xu C, Liu J, Gao L, Zhao C, Wang Z, Zhong Y, Wang X
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119813
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119813
SLAMF8 regulates osteogenesis and adipogenesis of bone marrow mesenchymal stem cells via S100A6/Wnt/β-catenin signaling pathway.
Wang Y, Hang K, Wu X, Ying L, Wang Z, Ling Z, Hu H, Pan Z, Zou X
Stem cell research & therapy 2024 Oct 8;15(1):349
Stem cell research & therapy 2024 Oct 8;15(1):349
Co-Mn Complex Oxide Nanoparticles as Potential Reactive Oxygen Species Scavenging Agents for Pulmonary Fibrosis Treatment.
Yang W, Yuan H, Sun H, Hu T, Xu Y, Qiu Y, Li Y
Molecules (Basel, Switzerland) 2024 Oct 29;29(21)
Molecules (Basel, Switzerland) 2024 Oct 29;29(21)
The Functional Role of the Long Non-Coding RNA LINCMD1 in Leiomyoma Pathogenesis.
Chuang TD, Ton N, Rysling S, Khorram O
International journal of molecular sciences 2024 Oct 27;25(21)
International journal of molecular sciences 2024 Oct 27;25(21)
Astragaloside I Promotes Lipophagy and Mitochondrial Biogenesis to Improve Hyperlipidemia by Regulating Akt/mTOR/TFEB Pathway.
Zhao J, Gao G, Ding J, Liu W, Wang T, Zhao L, Xu J, Zhang Z, Zhang X, Xie Z
Journal of agricultural and food chemistry 2024 Oct 2;72(39):21548-21559
Journal of agricultural and food chemistry 2024 Oct 2;72(39):21548-21559
Construction of an interactome network among circRNA-miRNA-mRNA reveals new biomarkers in hBMSCs osteogenic differentiation.
Su K, Cui X, Zhou J, Yi Q, Liu O
Scientific reports 2024 Oct 18;14(1):24507
Scientific reports 2024 Oct 18;14(1):24507
NIR-II light based combinatorial management of hypertrophic scar by inducing autophagy in fibroblasts.
Dong Y, Wang H, Zhang Y, Wu Y, Lu L, Yu H, Zhou L, Zhao P, Ouyang S, Song Z, Hu Z, Lv D, Rong Y, Zhao Z, Tao J, Tang B, Luo S
Journal of nanobiotechnology 2024 Oct 15;22(1):625
Journal of nanobiotechnology 2024 Oct 15;22(1):625
Preliminary study of the role of histone deacetylase (HDAC) in steroid-induced avascular necrosis of the femoral head induced by BMSC adipogenic differentiation.
Yu YL, Duan P, Zheng L, Xu JM, Pan ZY
Journal of orthopaedic surgery and research 2024 Oct 12;19(1):645
Journal of orthopaedic surgery and research 2024 Oct 12;19(1):645
Biodegradable Piezoelectric-Conductive Integrated Hydrogel Scaffold for Repair of Osteochondral Defects.
Liu D, Wang X, Gao C, Zhang Z, Wang Q, Pei Y, Wang H, Tang Y, Li K, Yu Y, Cai Q, Zhang X
Advanced materials (Deerfield Beach, Fla.) 2024 Nov;36(45):e2409400
Advanced materials (Deerfield Beach, Fla.) 2024 Nov;36(45):e2409400
Nuclear translocation of SIRT4 mediates deacetylation of U2AF2 to modulate renal fibrosis through alternative splicing-mediated upregulation of CCN2.
Yang G, Xiang J, Yang X, Liu X, Li Y, Li L, Kang L, Liang Z, Yang S
eLife 2024 Nov 4;13
eLife 2024 Nov 4;13
Granzyme K(+)CD8(+) T cells interact with fibroblasts to promote neutrophilic inflammation in nasal polyps.
Guo CL, Wang CS, Wang ZC, Liu FF, Liu L, Yang Y, Li X, Guo B, Lu RY, Liao B, Liu JX, Wang H, Song J, Yao Y, Zhu LP, Yu D, Liu Z
Nature communications 2024 Nov 29;15(1):10413
Nature communications 2024 Nov 29;15(1):10413
Sele-targeted siRNA liposome nanoparticles inhibit pathological scars formation via blocking the cross-talk between monocyte and endothelial cells: a preclinical study based on a novel mice scar model.
Li L, Wang Y, Meng J, Wang X, Wu X, Wo Y, Shang Y, Zhang Z
Journal of nanobiotechnology 2024 Nov 27;22(1):733
Journal of nanobiotechnology 2024 Nov 27;22(1):733
Zfp260 choreographs the early stage osteo-lineage commitment of skeletal stem cells.
Weng Y, Feng Y, Li Z, Xu S, Wu D, Huang J, Wang H, Wang Z
Nature communications 2024 Nov 24;15(1):10186
Nature communications 2024 Nov 24;15(1):10186
Tumor microenvironment remodeling after neoadjuvant chemoradiotherapy in local advanced rectal cancer revealed by single-cell RNA sequencing.
Su W, Ling Y, Yang X, Wu Y, Xing C
Journal of translational medicine 2024 Nov 18;22(1):1037
Journal of translational medicine 2024 Nov 18;22(1):1037
Ulinastatin attenuates renal fibrosis by regulating AMPK/HIF-1α signaling pathway-mediated glycolysis.
Wei X, Long M, Fan Z, Hou Y, Yang L, Du Y
Scientific reports 2024 Nov 14;14(1):28032
Scientific reports 2024 Nov 14;14(1):28032
Alarmin-loaded extracellular lipid droplets induce airway neutrophil infiltration during type 2 inflammation.
Rao Z, Liu S, Li Z, Wang Q, Gao F, Peng H, Ren D, Zang Y, Li H, Li Y, Hu Q, He D, Xu H
Immunity 2024 Nov 12;57(11):2514-2529.e7
Immunity 2024 Nov 12;57(11):2514-2529.e7
Uniaxial static strain enhances osteogenic and angiogenic potential under hypoxic conditions in distraction osteogenesis.
Zhang L, Peng Y, Guo T, Fang W, Li Z, Yang X
Journal of orthopaedic surgery and research 2024 Nov 1;19(1):711
Journal of orthopaedic surgery and research 2024 Nov 1;19(1):711
Identification of ROS and KEAP1-related genes and verified targets of α-hederin induce cell death for CRC.
Wang G, Zhu ZM, Wang K
Drug development research 2024 May;85(3):e22200
Drug development research 2024 May;85(3):e22200
Effects of Nanoparticle-Mediated Dihydromyricetin to Diabetic Wounds: An In Vivo Study.
Wang ZN, Ma JC, Xi MF, Yin D, Jiang LF, Qi J
Journal of burn care & research : official publication of the American Burn Association 2024 May 6;45(3):644-654
Journal of burn care & research : official publication of the American Burn Association 2024 May 6;45(3):644-654
Human amnion mesenchymal stem cells promote endometrial repair via paracrine, preferentially than transdifferentiation.
Huang X, Yang X, Huang J, Wei L, Mao Y, Li C, Zhang Y, Chen Q, Wu S, Xie L, Sun C, Zhang W, Wang J
Cell communication and signaling : CCS 2024 May 31;22(1):301
Cell communication and signaling : CCS 2024 May 31;22(1):301
The Bioactive Compounds of Epimedium and Their Potential Mechanism of Action in Treating Osteoporosis: A Network Pharmacology and Experimental Validation Study.
Dong H, Tang F, Zhao Z, Huang W, Wan X, Hong Z, Liu Y, Dong X, Chen S
Pharmaceuticals (Basel, Switzerland) 2024 May 29;17(6)
Pharmaceuticals (Basel, Switzerland) 2024 May 29;17(6)
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
Wang L, Li C, Zhan H, Li S, Zeng K, Xu C, Zou Y, Xie Y, Zhan Z, Yin S, Zeng Y, Chen X, Lv G, Han Z, Zhou D, Zhou D, Yang Y, Zhou A
Cell reports. Medicine 2024 May 21;5(5):101533
Cell reports. Medicine 2024 May 21;5(5):101533
Lactate facilitated mitochondrial fission-derived ROS to promote pulmonary fibrosis via ERK/DRP-1 signaling.
Sun Z, Ji Z, Meng H, He W, Li B, Pan X, Zhou Y, Yu G
Journal of translational medicine 2024 May 21;22(1):479
Journal of translational medicine 2024 May 21;22(1):479
Neferine mitigates angiotensin II-induced atrial fibrillation and fibrosis via upregulation of Nrf2/HO-1 and inhibition of TGF-β/p-Smad2/3 pathways.
Jiang XX, Zhang R, Wang HS
Aging 2024 May 21;16(10):8630-8644
Aging 2024 May 21;16(10):8630-8644
Multi-omics integration highlights the role of ubiquitination in endometriosis fibrosis.
Yang M, Jiang H, Ding X, Zhang L, Zhang H, Chen J, Li L, He X, Huang Z, Chen Q
Journal of translational medicine 2024 May 12;22(1):445
Journal of translational medicine 2024 May 12;22(1):445
3D Printed Porous Zirconia Biomaterials based on Triply Periodic Minimal Surfaces Promote Osseointegration In Vitro by Regulating Osteoimmunomodulation and Osteo/Angiogenesis.
Jiang C, Ding M, Zhang J, Zhu C, Qin W, Zhao Z, Jiao T
ACS applied materials & interfaces 2024 Mar 27;16(12):14548-14560
ACS applied materials & interfaces 2024 Mar 27;16(12):14548-14560
An immune cell map of human lung adenocarcinoma development reveals an anti-tumoral role of the Tfh-dependent tertiary lymphoid structure.
Liu W, You W, Lan Z, Ren Y, Gao S, Li S, Chen WW, Huang C, Zeng Y, Xiao N, Wang Z, Xie H, Ma H, Chen Y, Wang G, Chen C, Li H
Cell reports. Medicine 2024 Mar 19;5(3):101448
Cell reports. Medicine 2024 Mar 19;5(3):101448
Revealing PPP1R12B and COL1A1 as piRNA pathway genes contributing to abdominal aortic aneurysm through integrated analysis and experimental validation.
Jia D, Wang K, Huang L, Zhou Z, Zhang Y, Chen N, Yang Q, Wen Z, Jiang H, Yao C, Wu R
Gene 2024 Mar 1;897:148068
Gene 2024 Mar 1;897:148068
Bicyclol Alleviates Streptozotocin-induced Diabetic Cardiomyopathy By Inhibiting Chronic Inflammation And Oxidative Stress.
Zhang L, Hu C, Jin B, Bai B, Liao J, Jin L, Wang M, Zhu W, Wu X, Zheng L, Xu X, Jiang Y, Wang Y, He Y
Cardiovascular drugs and therapy 2024 Jun;38(3):555-568
Cardiovascular drugs and therapy 2024 Jun;38(3):555-568
CircZfp644-205 inhibits osteoblast differentiation and induces apoptosis of pre-osteoblasts via sponging miR-455-3p and promoting SMAD2 expression.
Zhang P, Liu J, Chai Z, Fu J, Li S, Yang Z
European journal of medical research 2024 Jun 8;29(1):315
European journal of medical research 2024 Jun 8;29(1):315
Bioactive compound schaftoside from Clinacanthus nutans attenuates acute liver injury by inhibiting ferroptosis through activation the Nrf2/GPX4 pathway.
Yu Y, Liang J, Yuan Z, Wang A, Liu X, Chen Y, Zhang M, Gao Y, Zhang H, Liu Y
Journal of ethnopharmacology 2024 Jun 28;328:118135
Journal of ethnopharmacology 2024 Jun 28;328:118135
Multiomic analysis of monocyte-derived alveolar macrophages in idiopathic pulmonary fibrosis.
Zhang M, Zhang J, Hu H, Zhou Y, Lin Z, Jing H, Sun B
Journal of translational medicine 2024 Jun 27;22(1):598
Journal of translational medicine 2024 Jun 27;22(1):598
Exosomal miR-17-5p derived from epithelial cells is involved in aberrant epithelium-fibroblast crosstalk and induces the development of oral submucosal fibrosis.
Xie C, Zhong L, Feng H, Wang R, Shi Y, Lv Y, Hu Y, Li J, Xiao D, Liu S, Chen Q, Tao Y
International journal of oral science 2024 Jun 20;16(1):48
International journal of oral science 2024 Jun 20;16(1):48
Silibinin attenuates TGF-β2-induced fibrogenic changes in human trabecular meshwork cells by targeting JAK2/STAT3 and PI3K/AKT signaling pathways.
Wu X, Liang J, Liu J, Huang Y, Zhang L, Liu X, Guo J, Zhang M, Chen Y, Wang J
Experimental eye research 2024 Jul;244:109939
Experimental eye research 2024 Jul;244:109939
The EPRS-ATF4-COLI pathway axis is a potential target for anaplastic thyroid carcinoma therapy.
Mi L, Liu J, Zhang Y, Su A, Tang M, Xing Z, He T, Wei T, Li Z, Wu W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155670
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155670
Adiponectin inhibits ROS/NLRP3 inflammatory pathway through FOXO3A to ameliorate oral submucosal fibrosis.
Zeng Y, Luo M, Yao Z, Xiao X
Odontology 2024 Jul;112(3):811-825
Odontology 2024 Jul;112(3):811-825
Dendrobine Ameliorates Glucocorticoid-Induced Osteoporosis by Promoting Osteogenesis through JNK/p38 MAPK Pathway Activation and GR Nuclear Translocation Inhibition.
Li X, Gao C, Zhou K, Gan K, Ye T, Zhao J, Li J, Ma C
Journal of agricultural and food chemistry 2024 Jul 31;72(30):16739-16748
Journal of agricultural and food chemistry 2024 Jul 31;72(30):16739-16748
Varied cellular abnormalities in thin vs. normal endometrium in recurrent implantation failure by single-cell transcriptomics.
Fu X, Guo X, Xu H, Li Y, Jin B, Zhang X, Shu C, Fan Y, Yu Y, Tian Y, Tian J, Shu J
Reproductive biology and endocrinology : RB&E 2024 Jul 31;22(1):90
Reproductive biology and endocrinology : RB&E 2024 Jul 31;22(1):90
The miR-15b-5p/miR-379-3p-FOXO axis regulates cell cycle and apoptosis in scleral remodeling during experimental myopia.
Zhang R, Wen Y, Liu J, Hao J, Peng Y, Zhang M, Xie Y, Yang Z, Yin X, Shi Y, Bi H, Guo D
Journal of translational medicine 2024 Jul 30;22(1):710
Journal of translational medicine 2024 Jul 30;22(1):710
Zhen-wu-tang protects against myocardial fibrosis by inhibiting M1 macrophage polarization via the TLR4/NF-κB pathway.
Fang R, Zhou R, Ju D, Li M, Wang H, Pan L, Wang X, Han M, Yu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155719
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155719
The ANGPTL4-HIF-1α loop: a critical regulator of renal interstitial fibrosis.
Li Y, Chen S, Yang Q, Liu X, Zhou W, Kang T, Wu W, Ou S
Journal of translational medicine 2024 Jul 11;22(1):649
Journal of translational medicine 2024 Jul 11;22(1):649
Single-Cell RNA Transcriptome of the Human Endometrium Reveals Epithelial Characterizations Associated with Recurrent Implantation Failure.
Zhang H, Zhang C, Zhang S
Advanced biology 2024 Jan;8(1):e2300110
Advanced biology 2024 Jan;8(1):e2300110
Uric acid promotes interleukin-17 expression to cause kidney injury.
Yang L, He T, Yu Y
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23550
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23550
Metabolic reprogramming driven by EZH2 inhibition depends on cell-matrix interactions.
W-M Fan T, Islam JMM, Higashi RM, Lin P, Brainson CF, Lane AN
The Journal of biological chemistry 2024 Jan;300(1):105485
The Journal of biological chemistry 2024 Jan;300(1):105485
Lactate accumulation induced by Akt2-PDK1 signaling promotes pulmonary fibrosis.
Sun Z, Ji Z, He W, Duan R, Qu J, Yu G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23426
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23426
Biomimetic cryogel promotes the repair of osteoporotic bone defects through altering the ROS niche via down-regulating the ROMO1.
Liu H, Pan W, Liu H, Xie D, Liao L
International journal of biological macromolecules 2024 Feb;257(Pt 1):128481
International journal of biological macromolecules 2024 Feb;257(Pt 1):128481
Role of IFITM2 in osteogenic differentiation of C3H10T1/2 mesenchymal stem cells.
Zhang Y, Li X, Zhang S, Li J, Liu M, Lu Y, Han J
Intractable & rare diseases research 2024 Feb;13(1):42-50
Intractable & rare diseases research 2024 Feb;13(1):42-50
Single-Nucleus RNA Sequencing Unravels Early Mechanisms of Human Becker Muscular Dystrophy.
Xie Z, Liu C, Sun C, Liu Y, Peng J, Meng L, Deng J, Wang Z, Yang C, Yuan Y, Xie Z
Annals of neurology 2024 Dec;96(6):1070-1085
Annals of neurology 2024 Dec;96(6):1070-1085
Scaffold loaded LPS-hUCMSC-sEVs promote Osteo/odontogenic differentiation and angiogenic potential of hDPSCs.
Zeng J, Deng H, Li Q, Kang J, Wu Y
Tissue & cell 2024 Dec;91:102549
Tissue & cell 2024 Dec;91:102549
Geniposide alleviates heart failure with preserved ejection fraction in mice by regulating cardiac oxidative stress via MMP2/SIRT1/GSK3β pathway.
Han YL, Yan TT, Li HX, Chen SS, Zhang ZZ, Wang MY, Chen MJ, Chen YL, Yang XX, Wei LL, Duan YJ, Zhang S
Acta pharmacologica Sinica 2024 Dec;45(12):2567-2578
Acta pharmacologica Sinica 2024 Dec;45(12):2567-2578
Calpain-1 Up-Regulation Promotes Bleomycin-Induced Pulmonary Fibrosis by Activating Ferroptosis.
Wei S, Liu Y, Ran C, Li Y, Tang B, Lu M, Wang H
The American journal of pathology 2024 Dec;194(12):2272-2289
The American journal of pathology 2024 Dec;194(12):2272-2289
Single-cell RNA transcriptomics reveals Du-Zhong-Wan promotes osteoporotic fracture healing via YAP/β-catenin/VEGF axis in BMSCs.
Dong R, Wei J, Tian S, Wang J, Ma Y, Li Y, Liu RX, Liu YQ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:155572
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:155572
A 0.2 T-0.4 T Static Magnetic Field Improves the Bone Quality of Mice Subjected to Hindlimb Unloading and Reloading Through the Dual Regulation of BMSCs via Iron Metabolism.
Wang J, Zhen C, Zhang G, Yang Z, Shang P
International journal of molecular sciences 2024 Dec 6;25(23)
International journal of molecular sciences 2024 Dec 6;25(23)
SPDEF ameliorates UUO-induced renal fibrosis by transcriptional activation of NR4A1.
Wang H, Wei Z, Xu C, Fang F, Wang Z, Zhong Y, Wang X
Molecular medicine (Cambridge, Mass.) 2024 Dec 30;30(1):282
Molecular medicine (Cambridge, Mass.) 2024 Dec 30;30(1):282
Tubuloside A alleviates postmyocardial infarction cardiac fibrosis by inhibiting TGM2: Involvement of inflammation and mitochondrial pathway apoptosis.
Sun R, Li H, Chen Y, Hu M, Wang J
International immunopharmacology 2024 Dec 25;143(Pt 1):113324
International immunopharmacology 2024 Dec 25;143(Pt 1):113324
Myricetin Alleviates Silica-Mediated Lung Fibrosis via PPARγ-PGC-1α Loop and Suppressing Mitochondrial Senescence in Epithelial Cells.
Xie W, Deng L, Zhang X, Huang X, Ding J, Liu W, Tang SY
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27737-27749
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27737-27749
Magnetically Induced Anisotropic Microstructures on Polyethylene Glycol Hydrogel Facilitate BMSC Alignment and Osteogenic Differentiation.
Zhang H, Luo Y, Xu R, Cao X, Li G, Chen S
Gels (Basel, Switzerland) 2024 Dec 11;10(12)
Gels (Basel, Switzerland) 2024 Dec 11;10(12)
Exome-wide association study identifies KDELR3 mutations in extreme myopia.
Yuan J, Zhuang YY, Liu X, Zhang Y, Li K, Chen ZJ, Li D, Chen H, Liang J, Yao Y, Yu X, Zhuo R, Zhao F, Zhou X, Myopia Associated Genetics and Intervention Consortium, Yu X, Qu J, Su J
Nature communications 2024 Aug 7;15(1):6703
Nature communications 2024 Aug 7;15(1):6703
Expression of insulin-like growth factor binding protein 5 in the vaginal wall tissues of older women with pelvic organ prolapse.
Duan Y, Chen Y, He Y, Gong R, Xia Z
Scientific reports 2024 Aug 7;14(1):18353
Scientific reports 2024 Aug 7;14(1):18353
ENG is a Biomarker of Prognosis and Angiogenesis in Liver Cancer, and Promotes the Differentiation of Tumor Cells into Vascular ECs.
Shi S, Zhu C, Hu Y, Jiang P, Zhao J, Xu Q
Frontiers in bioscience (Landmark edition) 2024 Aug 30;29(9):315
Frontiers in bioscience (Landmark edition) 2024 Aug 30;29(9):315
Cryptotanshinone alleviates liver fibrosis via inhibiting STAT3/CPT1A-dependent fatty acid oxidation in hepatic stellate cells.
Li Z, Zheng Y, Zhang L, Xu E
Chemico-biological interactions 2024 Aug 25;399:111119
Chemico-biological interactions 2024 Aug 25;399:111119
Phosphodiesterase type 5 inhibitor tadalafil reduces prostatic fibrosis via MiR-3126-3p/FGF9 axis in benign prostatic hyperplasia.
Li T, Zhang Y, Zhou Z, Guan L, Zhang Y, Zhou Z, Wang W, Zhou X, Cui D, Jiang C, Ruan Y
Biology direct 2024 Aug 2;19(1):61
Biology direct 2024 Aug 2;19(1):61
System analysis based on weighted gene co-expression analysis identifies SOX7 as a novel regulator of hepatic stellate cell activation and liver fibrosis.
Liu Y, Wang X, Wang Z, Gao X, Xu H, Gao Y, Niu J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 15;38(15):e23495
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 15;38(15):e23495
Suppression of NUPR1 in fibroblast-like synoviocytes reduces synovial fibrosis via the Smad3 pathway.
Liao T, Shi L, He C, Liu D, Wei Y, Ma Z, Wang P, Mao J, Wu P
Journal of translational medicine 2024 Aug 1;22(1):715
Journal of translational medicine 2024 Aug 1;22(1):715
Chronic exposure to BDE-47 aggravates acute pancreatitis and chronic pancreatitis by promoting acinar cell apoptosis and inflammation.
Qi X, Liu Q, Wei Z, Hou X, Jiang Y, Sun Y, Xu S, Yang L, He J, Liu K
Toxicological sciences : an official journal of the Society of Toxicology 2024 Apr 29;199(1):120-131
Toxicological sciences : an official journal of the Society of Toxicology 2024 Apr 29;199(1):120-131
Identification of a circulating three-miRNA panel for the diagnosis of primary open angle glaucoma.
Qin B, Li LP, Xu QD, Lei Y, Chen YH
International ophthalmology 2024 Apr 15;44(1):176
International ophthalmology 2024 Apr 15;44(1):176
PM2.5 exposure-induced senescence-associated secretory phenotype in airway smooth muscle cells contributes to airway remodeling.
Cheng PP, Yu F, Chen SJ, Feng X, Jia ZH, Hu SH, Cui XL, Zhou YY, Niu Q, Liang LM, Wang M, Song LJ, He XL, Xiong L, Xiang F, Wang X, Ma WL, Ye H
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123674
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123674
Cellular senescence and metabolic reprogramming model based on bulk/single-cell RNA sequencing reveals PTGER4 as a therapeutic target for ccRCC.
Zhou L, Zeng Y, Liu Y, Du K, Luo Y, Dai Y, Pan W, Zhang L, Zhang L, Tian F, Gu C
BMC cancer 2024 Apr 11;24(1):451
BMC cancer 2024 Apr 11;24(1):451
Comparison studies identify mesenchymal stromal cells with potent regenerative activity in osteoarthritis treatment.
Chu H, Zhang S, Zhang Z, Yue H, Liu H, Li B, Yin F
NPJ Regenerative medicine 2024 Apr 1;9(1):14
NPJ Regenerative medicine 2024 Apr 1;9(1):14
Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS.
Luo J, Liu J, Mou Y, Luo F, Liao Q, Liao Y
The Journal of toxicological sciences 2023;48(6):345-354
The Journal of toxicological sciences 2023;48(6):345-354
Downregulation of KIAA1199 alleviated the activation, proliferation, and migration of hepatic stellate cells by the inhibition of epithelial-mesenchymal transition.
Liu J, Xia S, Han P, Zhang M, Wu J, Liao J
Open medicine (Warsaw, Poland) 2023;18(1):20230689
Open medicine (Warsaw, Poland) 2023;18(1):20230689
GLIS2 Prevents Hepatic Fibrosis by Competitively Binding HDAC3 to Inhibit Hepatic Stellate Cell Activation.
Zhang H, Zhou P, Xing W, Chen L, Zhou Y, Yang H, Fu K, Liu Z
Cellular and molecular gastroenterology and hepatology 2023;15(2):355-372
Cellular and molecular gastroenterology and hepatology 2023;15(2):355-372
Chrysin ameliorates synovitis and fibrosis of osteoarthritic fibroblast-like synoviocytes in rats through PERK/TXNIP/NLRP3 signaling.
Ding L, Liao T, Yang N, Wei Y, Xing R, Wu P, Li X, Mao J, Wang P
Frontiers in pharmacology 2023;14:1170243
Frontiers in pharmacology 2023;14:1170243
Thymoquinone affects the gemcitabine sensitivity of pancreatic cancer by regulating collagen via hypoxia inducible factor-1α.
Zhao Z, Liu L, Chen H, Li S, Guo Y, Hou X, Yang J
Frontiers in pharmacology 2023;14:1138265
Frontiers in pharmacology 2023;14:1138265
A novel signature of aging-related genes associated with lymphatic metastasis for survival prediction in patients with bladder cancer.
Zhu Z, Li X, Liu D, Li Z
Frontiers in oncology 2023;13:1140891
Frontiers in oncology 2023;13:1140891
Extracellular ATP-induced calcium oscillations regulating the differentiation of osteoblasts through aerobic oxidation metabolism pathways.
Gao X, Di X, Li J, Kang Y, Xie W, Sun L, Zhang J
Journal of bone and mineral metabolism 2023 Sep;41(5):606-620
Journal of bone and mineral metabolism 2023 Sep;41(5):606-620
α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure.
Zhang N, Zhang Y, Xu J, Wang P, Wu B, Lu S, Lu X, You S, Huang X, Li M, Zou Y, Liu M, Zhao Y, Sun G, Wang W, Geng D, Liu J, Cao L, Sun Y
Cell research 2023 Sep;33(9):679-698
Cell research 2023 Sep;33(9):679-698
Photobiomodulation at 660 nm promotes collagen synthesis via downregulation of HIF-1α expression without photodamage in human scleral fibroblasts in vitro in a hypoxic environment.
Zhang P, Zhang X, Zhu H
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2023 Sep;261(9):2535-2545
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2023 Sep;261(9):2535-2545
SIRT3 regulates mitophagy in liver fibrosis through deacetylation of PINK1/NIPSNAP1.
Li R, Wang Z, Wang Y, Sun R, Zou B, Tian X, Liu D, Zhao X, Zhou J, Zhao Y, Yao J
Journal of cellular physiology 2023 Sep;238(9):2090-2102
Journal of cellular physiology 2023 Sep;238(9):2090-2102
A multifunctional polydopamine/genipin/alendronate nanoparticle licences fibrin hydrogels osteoinductive and immunomodulatory potencies for repairing bone defects.
Shi W, Gao Y, Wu Y, Sun J, Xu B, Lu X, Wang Q
International journal of biological macromolecules 2023 Sep 30;249:126072
International journal of biological macromolecules 2023 Sep 30;249:126072
PDK4 facilitates fibroblast functions and diabetic wound healing through regulation of HIF-1α protein stability and gene expression.
Ma Z, Mo R, Yang P, Ding Y, Zhang H, Dong Z, Chen Y, Tan Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23215
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23215
Fu-Zheng-Tong-Luo formula promotes autophagy and alleviates idiopathic pulmonary fibrosis by controlling the Janus kinase 2/signal transducer and activator of transcription 3 pathway.
Zhang X, Su J, Lin J, Liu L, Wu J, Yuan W, Zhang Y, Chen Q, Su ZJ, Xu G, Sun M, Zhang Y, Chen X, Zhang W
Journal of ethnopharmacology 2023 Oct 5;314:116633
Journal of ethnopharmacology 2023 Oct 5;314:116633
The Dual-Mode Transition of Myofibroblasts Derived from Hepatic Stellate Cells in Liver Fibrosis.
Yan M, Xie Y, Yao J, Li X
International journal of molecular sciences 2023 Oct 23;24(20)
International journal of molecular sciences 2023 Oct 23;24(20)
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
Song K, Sun H, Tu B, Zhou Y, Lin LC, Liu ZY, Li R, Yang JJ, Zhang Y, Zhao JY, Tao H
iScience 2023 Oct 20;26(10):107931
iScience 2023 Oct 20;26(10):107931
Dihydroartemisinin inhibits the activation and proliferation of hepatic stellate cells by regulating miR‑29b‑3p.
Huan S, Sun S, Song S, Dai J, Zhu G, Zhong Y, Ji Y, Zheng S, Yin G
International journal of molecular medicine 2023 May;51(5)
International journal of molecular medicine 2023 May;51(5)
Schistosome egg antigen stimulates the secretion of miR-33-carrying extracellular vesicles from macrophages to promote hepatic stellate cell activation and liver fibrosis in schistosomiasis.
Qi X, Pu Y, Chen F, Dong L, Ma Y, Wang J, Yin G, Lu D, Chen X, Zhu J, Li Y, Zhou S, Su C
PLoS neglected tropical diseases 2023 May;17(5):e0011385
PLoS neglected tropical diseases 2023 May;17(5):e0011385
GATA6 triggers fibroblast activation and tracheal fibrosis through the Wnt/β-catenin pathway.
Li A, Gu L, Mu J, Li Y, Wang X, Jiang J, Bai Y, Yang M, He C, Xiao R, Liao J, Jin X, Xiao M, Xiao Y, Zhang X, Tan T, Peng M, Xu L, Guo S
Cellular signalling 2023 May;105:110593
Cellular signalling 2023 May;105:110593
Yishen Tongluo formula alleviates diabetic kidney disease through regulating Sirt6/TGF-β1/Smad2/3 pathway and promoting degradation of TGF-β1.
Zhang X, Zhao L, Xiang S, Sun Y, Wang P, Chen JJ, Teo BS, Xie Z, Zhang Z, Xu J
Journal of ethnopharmacology 2023 May 10;307:116243
Journal of ethnopharmacology 2023 May 10;307:116243
Taohong Siwu Decoction enhances human bone marrow mesenchymal stem cells proliferation, migration and osteogenic differentiation via VEGF-FAK signaling in vitro.
Lu X, Li J, Zhou B, Lu X, Li W, Ouyang J
Journal of ethnopharmacology 2023 May 10;307:116203
Journal of ethnopharmacology 2023 May 10;307:116203
Hypoxia-Induced Kidney Injury in Newborn Rats.
Chu YT, Chen BH, Chen HH, Lee JC, Kuo TJ, Chiu HC, Lu WH
Toxics 2023 Mar 11;11(3)
Toxics 2023 Mar 11;11(3)
Tabersonine attenuates obesity-induced renal injury via inhibiting NF-κB-mediated inflammation.
Qian C, Wang J, Lin W, Chen Y, Yang J, Liu M, Sun X, Wu H, Zhang M, Wang Y, Cao S
Phytotherapy research : PTR 2023 Jun;37(6):2353-2363
Phytotherapy research : PTR 2023 Jun;37(6):2353-2363
Ellagic acid inhibits CDK12 to increase osteoblast differentiation and alleviate osteoporosis in hindlimb-unloaded and ovariectomized mice.
Wu Z, Hu L, Ru K, Zhang W, Xu X, Liu S, Liu H, Jia Y, Liang S, Chen Z, Qian A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154745
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154745
Silencing of NOTCH3 Signaling in Meniscus Smooth Muscle Cells Inhibits Fibrosis and Exacerbates Degeneration in a HEYL-Dependent Manner.
Sun H, Liu F, Lin Z, Jiang Z, Wen X, Xu J, Zhang Z, Ma R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(16):e2207020
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(16):e2207020
Macrophage Dectin-1 mediates Ang II renal injury through neutrophil migration and TGF-β1 secretion.
Ye S, Huang H, Xiao Y, Han X, Shi F, Luo W, Chen J, Ye Y, Zhao X, Huang W, Wang Y, Lai D, Liang G, Fu G
Cellular and molecular life sciences : CMLS 2023 Jun 20;80(7):184
Cellular and molecular life sciences : CMLS 2023 Jun 20;80(7):184
Total flavonoid extract from Dracocephalum moldavica L. improves pulmonary fibrosis by reducing inflammation and inhibiting the hedgehog signaling pathway.
He CH, Lv JM, Khan GJ, Duan H, Wang W, Zhai KF, Zou GA, Aisa HA
Phytotherapy research : PTR 2023 Jul;37(7):2745-2758
Phytotherapy research : PTR 2023 Jul;37(7):2745-2758
Fibroblast growth factor 10 delays the progression of osteoarthritis by attenuating synovial fibrosis via inhibition of IL-6/JAK2/STAT3 signaling in vivo and in vitro.
Su W, Zheng X, Zhou H, Yang S, Zhu X
Molecular immunology 2023 Jul;159:46-57
Molecular immunology 2023 Jul;159:46-57
LAMP2A regulates the balance of mesenchymal stem cell adipo-osteogenesis via the Wnt/β-catenin/GSK3β signaling pathway.
Wang Y, Hang K, Ying L, Wu J, Wu X, Zhang W, Li L, Wang Z, Bai J, Gao X, Xue D, Pan Z
Journal of molecular medicine (Berlin, Germany) 2023 Jul;101(7):783-799
Journal of molecular medicine (Berlin, Germany) 2023 Jul;101(7):783-799
Identification of Immune Infiltration in Odontogenic Keratocyst by Integrated Bioinformatics Analysis.
Zhong NN, Li SR, Man QW, Liu B
BMC oral health 2023 Jul 6;23(1):454
BMC oral health 2023 Jul 6;23(1):454
Metformin suppressed tendon injury-induced adhesion via hydrogel-nanoparticle sustained-release system.
Jie Li Z, Bing Luo C, Liang Wang H, Sun J, Qian Yang Q, Lang Zhou Y
International journal of pharmaceutics 2023 Jul 25;642:123190
International journal of pharmaceutics 2023 Jul 25;642:123190
Atractylenolide III Ameliorates Bile Duct Ligation-Induced Liver Fibrosis by Inhibiting the PI3K/AKT Pathway and Regulating Glutamine Metabolism.
Wang Y, Shi K, Tu J, Ke C, Chen N, Wang B, Liu Y, Zhou Z
Molecules (Basel, Switzerland) 2023 Jul 19;28(14)
Molecules (Basel, Switzerland) 2023 Jul 19;28(14)
Sodium houttuyfonate against cardiac fibrosis attenuates isoproterenol-induced heart failure by binding to MMP2 and p38.
Tan R, You Q, Cui J, Wang M, Song N, An K, Lin L, Adu-Amankwaah J, Yuan J, Sun H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154590
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154590
Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression.
Wei P, Lin D, Zhang M, Luo C, Wu X, Deng B, Cui K, Chen Z
European journal of pharmacology 2023 Jan 5;938:175434
European journal of pharmacology 2023 Jan 5;938:175434
20-Hydroxytetraenoic acid induces hepatic fibrosis via the TGF-β1/Smad3 signaling pathway.
Li B, Ma Y, Tan L, Ren H, Wu L, Su Q, Song J, Chen W, Gong P, Jin Y
Toxicology letters 2023 Jan 15;373:1-12
Toxicology letters 2023 Jan 15;373:1-12
The m6A demethylase FTO promotes keloid formation by up-regulating COL1A1.
Ren S, Ji Y, Wang M, Ye M, Huang L, Cai X
Annals of translational medicine 2023 Jan 15;11(1):15
Annals of translational medicine 2023 Jan 15;11(1):15
Alamandine/MrgD axis prevents TGF-β1-mediated fibroblast activation via regulation of aerobic glycolysis and mitophagy.
Wang W, Zhang Y, Huang W, Yuan Y, Hong Q, Xie Z, Li L, Chen Y, Li X, Meng Y
Journal of translational medicine 2023 Jan 13;21(1):24
Journal of translational medicine 2023 Jan 13;21(1):24
Effect of stretch frequency on osteogenesis of periodontium during periodontal ligament distraction.
Wang W, Li N, Zhao Y, Wu H, Wang M, Chen X
Orthodontics & craniofacial research 2023 Feb;26(1):53-61
Orthodontics & craniofacial research 2023 Feb;26(1):53-61
Autophagy loss impedes cancer-associated fibroblast activation via downregulating proline biosynthesis.
Bai J, Liu T, Tu B, Yuan M, Shu Z, Fan M, Huo S, Guo Y, Wang L, Wang H, Zhao Y
Autophagy 2023 Feb;19(2):632-643
Autophagy 2023 Feb;19(2):632-643
LncRNA H19-EZH2 interaction promotes liver fibrosis via reprogramming H3K27me3 profiles.
Li XJ, Zhou F, Li YJ, Xue XY, Qu JR, Fan GF, Liu J, Sun R, Wu JZ, Zheng Q, Liu RP
Acta pharmacologica Sinica 2023 Dec;44(12):2479-2491
Acta pharmacologica Sinica 2023 Dec;44(12):2479-2491
Obstructive sleep apnea promotes the progression of lung cancer by modulating cancer cell invasion and cancer-associated fibroblast activation via TGFβ signaling.
Cui Z, Ruan Z, Li M, Ren R, Ma Y, Zeng J, Sun J, Ye W, Xu W, Guo X, Xu D, Zhang L
Redox report : communications in free radical research 2023 Dec;28(1):2279813
Redox report : communications in free radical research 2023 Dec;28(1):2279813
Degradation Adaptability Assessment of Semisolid Powder Molded Mg-Zn-Mn Alloys for Orthopedic Applications.
Luo X, Li M, Cai H, Yang S, Hao L, Ebel T, Helmholz H, Huang B, Wang X
ACS applied bio materials 2023 Dec 18;6(12):5515-5530
ACS applied bio materials 2023 Dec 18;6(12):5515-5530
Neuropilin 1 promotes unilateral ureteral obstruction-induced renal fibrosis via RACK1 in renal tubular epithelial cells.
Hou L, Du Y
American journal of physiology. Renal physiology 2023 Dec 1;325(6):F870-F884
American journal of physiology. Renal physiology 2023 Dec 1;325(6):F870-F884
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
Sun J, Ju F, Jin J, Wang HL, Li ZJ, Sun YC, Chen QZ, Yang QQ, Tan J, Zhou YL
Small (Weinheim an der Bergstrasse, Germany) 2023 Aug;19(33):e2300326
Small (Weinheim an der Bergstrasse, Germany) 2023 Aug;19(33):e2300326
Dectin-1 deficiency alleviates diabetic cardiomyopathy by attenuating macrophage-mediated inflammatory response.
Yang N, Wang M, Lin K, Wang M, Xu D, Han X, Zhao X, Wang Y, Wu G, Luo W, Liang G, Shan P
Biochimica et biophysica acta. Molecular basis of disease 2023 Aug;1869(6):166710
Biochimica et biophysica acta. Molecular basis of disease 2023 Aug;1869(6):166710
LncRNA DGCR5-encoded polypeptide RIP aggravates SONFH by repressing nuclear localization of β-catenin in BMSCs.
Jiang W, Chen Y, Sun M, Huang X, Zhang H, Fu Z, Wang J, Zhang S, Lian C, Tang B, Xiang D, Wang Y, Zhang Y, Jian C, Yang C, Zhang J, Zhang D, Chen T, Zhang J
Cell reports 2023 Aug 29;42(8):112969
Cell reports 2023 Aug 29;42(8):112969
Knockdown of FBLN2 suppresses TGF-β1-induced MRC-5 cell migration and fibrosis by downregulating VTN.
Zhang Y, Zhang W, Zhang R, Xia Y
Tissue & cell 2023 Apr;81:102005
Tissue & cell 2023 Apr;81:102005
P4HA1, transcriptionally activated by STAT1, promotes esophageal cancer progression.
Gou W, Yang Y, Shan Q, Xia S, Ma Y
Pathology international 2023 Apr;73(4):147-158
Pathology international 2023 Apr;73(4):147-158
Activation of NRF2 Signaling Pathway Delays the Progression of Hyperuricemic Nephropathy by Reducing Oxidative Stress.
Qiao P, Sun Y, Wang Y, Lin S, An Y, Wang L, Liu J, Huang Y, Yang B, Zhou H
Antioxidants (Basel, Switzerland) 2023 Apr 28;12(5)
Antioxidants (Basel, Switzerland) 2023 Apr 28;12(5)
Single-Cell RNA-Sequencing Reveals the Cellular and Genetic Heterogeneity of Skin Scar to Verify the Therapeutic Effects and Mechanism of Action of Dispel-Scar Ointment in Hypertrophic Scar Inhibition.
Li Z, Yin L, Li Y, Cao Y, Zeng H
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7331164
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7331164
Cigarette Smoke Exposure Increases Glucose-6-phosphate Dehydrogenase, Autophagy, Fibrosis, and Senescence in Kidney Cells In Vitro and In Vivo.
Liu WC, Chuang HC, Chou CL, Lee YH, Chiu YJ, Wang YL, Chiu HW
Oxidative medicine and cellular longevity 2022;2022:5696686
Oxidative medicine and cellular longevity 2022;2022:5696686
Mechanism of Action of Zhi Gan Cao Decoction for Atrial Fibrillation and Myocardial Fibrosis in a Mouse Model of Atrial Fibrillation: A Network Pharmacology-Based Study.
Gao L, Kan C, Chen X, Xu S, Shi K
Computational and mathematical methods in medicine 2022;2022:4525873
Computational and mathematical methods in medicine 2022;2022:4525873
miR-486-5p Restrains Extracellular Matrix Production and Oxidative Damage in Human Trabecular Meshwork Cells by Targeting TGF-β/SMAD2 Pathway.
Xu L, Zhang Y, Long H, Zhou B, Jiang H
Journal of ophthalmology 2022;2022:3584192
Journal of ophthalmology 2022;2022:3584192
Ganfule capsule alleviates bile duct ligation-induced liver fibrosis in mice by inhibiting glutamine metabolism.
Ke C, Gao J, Tu J, Wang Y, Xiao Y, Wu Y, Liu Y, Zhou Z
Frontiers in pharmacology 2022;13:930785
Frontiers in pharmacology 2022;13:930785
QiShenYiQi Pill Ameliorates Cardiac Fibrosis After Pressure Overload-Induced Cardiac Hypertrophy by Regulating FHL2 and the Macrophage RP S19/TGF-β1 Signaling Pathway.
Anwaier G, Xie TT, Pan CS, Li AQ, Yan L, Wang D, Chen FK, Weng DZ, Sun K, Chang X, Fan JY, Han JY, Liu J
Frontiers in pharmacology 2022;13:918335
Frontiers in pharmacology 2022;13:918335
Beneficial Effect of Edoxaban on Preventing Atrial Fibrillation and Coagulation by Reducing Inflammation via HBG1/HBD Biomarkers.
Yang C, Wang X, Guo Y, Meng X, Li Y, Xia C, Meng L, Dong M, Wang F
Frontiers in pharmacology 2022;13:904317
Frontiers in pharmacology 2022;13:904317
Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway.
Li Z, Geng J, Xie B, He J, Wang J, Peng L, Hu Y, Dai H, Wang C
Frontiers in pharmacology 2022;13:834604
Frontiers in pharmacology 2022;13:834604
Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics.
Lin X, Wei Y, Li Y, Xiong Y, Fang B, Li C, Huang Q, Huang R, Wei J
Frontiers in pharmacology 2022;13:801982
Frontiers in pharmacology 2022;13:801982
Blockade of phosphotyrosine pathways suggesting SH2 superbinder as a novel therapy for pulmonary fibrosis.
Wang M, Liu AD, Niu Q, Feng X, Zheng YY, Chen SJ, Xu H, Li Q, Hou GQ, Bi XY, Lu YZ, Cheng PP, Liang LM, Jiang YH, Zhao LQ, Liu F, Song LJ, Zhou LL, Xiao LY, Chen F, Li SS, Ma WL, Cao X, Ye H
Theranostics 2022;12(10):4513-4535
Theranostics 2022;12(10):4513-4535
LARP6 Regulates Keloid Fibroblast Proliferation, Invasion, and Ability to Synthesize Collagen.
Chen L, Su Y, Yin B, Li S, Cheng X, He Y, Jia C
The Journal of investigative dermatology 2022 Sep;142(9):2395-2405.e7
The Journal of investigative dermatology 2022 Sep;142(9):2395-2405.e7
Knockdown of FOXA1 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the ERK1/2 signalling pathway.
Li L, Wang Y, Wang Z, Xue D, Dai C, Gao X, Ma J, Hang K, Pan Z
Stem cell research & therapy 2022 Sep 5;13(1):456
Stem cell research & therapy 2022 Sep 5;13(1):456
Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury.
Yao F, Luo Y, Liu YC, Chen YH, Li YT, Hu XY, You XY, Yu SS, Li ZY, Chen L, Tian DS, Zheng MG, Cheng L, Jing JH
Inflammation and regeneration 2022 Sep 26;42(1):44
Inflammation and regeneration 2022 Sep 26;42(1):44
miR-182-5p attenuates Schistosoma japonicum-induced hepatic fibrosis by targeting tristetraprolin.
Zhao X, Xia Z, Wang Z, Zhou M, Qiu X, Wang C, Xu T, Fang Q, Ming Z, Dong H
Acta biochimica et biophysica Sinica 2022 Sep 25;54(10):1421-1430
Acta biochimica et biophysica Sinica 2022 Sep 25;54(10):1421-1430
Carbon tetrachloride exposure induces ovarian damage through oxidative stress and inflammatory mediated ovarian fibrosis.
Xue L, Li X, Zhu X, Zhang J, Zhou S, Tang W, Chen D, Chen Y, Dai J, Wu M, Wu M, Wang S
Ecotoxicology and environmental safety 2022 Sep 1;242:113859
Ecotoxicology and environmental safety 2022 Sep 1;242:113859
Si-Wu-Tang ameliorates bile duct ligation-induced liver fibrosis via modulating immune environment.
Ma Z, Xue X, Bai J, Cai Y, Jin X, Jia K, Ding M, Lyu X, Li X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113834
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113834
Proteogenomic insights into the biology and treatment of pancreatic ductal adenocarcinoma.
Tong Y, Sun M, Chen L, Wang Y, Li Y, Li L, Zhang X, Cai Y, Qie J, Pang Y, Xu Z, Zhao J, Zhang X, Liu Y, Tian S, Qin Z, Feng J, Zhang F, Zhu J, Xu Y, Lou W, Ji Y, Zhao J, He F, Hou Y, Ding C
Journal of hematology & oncology 2022 Nov 25;15(1):168
Journal of hematology & oncology 2022 Nov 25;15(1):168
Macrophage-targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis.
Mou Y, Wu GR, Wang Q, Pan T, Zhang L, Xu Y, Xiong W, Zhou Q, Wang Y
Bioengineering & translational medicine 2022 May;7(2):e10280
Bioengineering & translational medicine 2022 May;7(2):e10280
Intracellular hydroxyproline imprinting following resolution of bleomycin-induced pulmonary fibrosis.
Song S, Fu Z, Guan R, Zhao J, Yang P, Li Y, Yin H, Lai Y, Gong G, Zhao S, Yu J, Peng X, He Y, Luo Y, Zhong N, Su J
The European respiratory journal 2022 May;59(5)
The European respiratory journal 2022 May;59(5)
ALKBH5 ameliorated liver fibrosis and suppressed HSCs activation via triggering PTCH1 activation in an m(6)A dependent manner.
Yang JJ, Wang J, Yang Y, Yang Y, Li J, Lu D, Lu C
European journal of pharmacology 2022 May 5;922:174900
European journal of pharmacology 2022 May 5;922:174900
Host liver-derived extracellular vesicles deliver miR-142a-3p induces neutrophil extracellular traps via targeting WASL to block the development of Schistosoma japonicum.
Wang L, Zhu Z, Liao Y, Zhang L, Yu Z, Yang R, Wu J, Wu Z, Sun X
Molecular therapy : the journal of the American Society of Gene Therapy 2022 May 4;30(5):2092-2107
Molecular therapy : the journal of the American Society of Gene Therapy 2022 May 4;30(5):2092-2107
Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis.
Qi W, Li X, Ren Y, Liu X, Fu H, Wang X, Li X, Xiong J, Zheng Q, Cai D, Liang F
Chinese medicine 2022 May 17;17(1):57
Chinese medicine 2022 May 17;17(1):57
Masquelet technique: Effects of vancomycin concentration on quality of the induced membrane.
Xie J, Wang W, Fan X, Li H, Wang H, Liao R, Hu Y, Zeng M
Injury 2022 Mar;53(3):868-877
Injury 2022 Mar;53(3):868-877
Overexpression of G Protein-Coupled Receptor 40 Protects Obesity-Induced Cardiomyopathy Through the SIRT1/LKB1/AMPK Pathway.
Li SN, Yu YL, Wang BY, Qiao SY, Hu MM, Wang H, Fu CN, Dong B
Human gene therapy 2022 Jun;33(11-12):598-613
Human gene therapy 2022 Jun;33(11-12):598-613
Suppression of the Inhibitory Effect of circ_0036176-Translated Myo9a-208 on Cardiac Fibroblast Proliferation by miR-218-5p.
Guo J, Chen LW, Huang ZQ, Guo JS, Li H, Shan Y, Chen ZR, Yan YM, Zhu JN, Guo HM, Fang XH, Shan ZX
Journal of cardiovascular translational research 2022 Jun;15(3):548-559
Journal of cardiovascular translational research 2022 Jun;15(3):548-559
ZIC5 promotes human hepatocellular carcinoma cell proliferation through upregulating COL1A1.
Song W, Yu W, Li D, Cheng C, Wu X, Chen J, Zhang W
Journal of gastrointestinal oncology 2022 Jun;13(3):1237-1247
Journal of gastrointestinal oncology 2022 Jun;13(3):1237-1247
Patient-derived microphysiological model identifies the therapeutic potential of metformin for thoracic aortic aneurysm.
Ma W, Zhang J, Liu S, Yan S, Xu K, Zhang YS, Abudupataer M, Ming Y, Zhu S, Xiang B, Zhou X, Luo S, Huang H, Tang Y, Zhang S, Xie Z, Chen N, Sun X, Li J, Lai H, Wang C, Zhu K, Zhang W
EBioMedicine 2022 Jul;81:104080
EBioMedicine 2022 Jul;81:104080
Hypoxia-Induced Scleral HIF-2α Upregulation Contributes to Rises in MMP-2 Expression and Myopia Development in Mice.
Wu W, Su Y, Hu C, Tao H, Jiang Y, Zhu G, Zhu J, Zhai Y, Qu J, Zhou X, Zhao F
Investigative ophthalmology & visual science 2022 Jul 8;63(8):2
Investigative ophthalmology & visual science 2022 Jul 8;63(8):2
Sustained release of naringin from silk-fibroin-nanohydroxyapatite scaffold for the enhancement of bone regeneration.
Zhao ZH, Ma XL, Ma JX, Kang JY, Zhang Y, Guo Y
Materials today. Bio 2022 Jan;13:100206
Materials today. Bio 2022 Jan;13:100206
Tartrate-resistant acid phosphatase 5 promotes pulmonary fibrosis by modulating β-catenin signaling.
Hu Y, Wang Q, Yu J, Zhou Q, Deng Y, Liu J, Zhang L, Xu Y, Xiong W, Wang Y
Nature communications 2022 Jan 10;13(1):114
Nature communications 2022 Jan 10;13(1):114
Bmal1 inhibits phenotypic transformation of hepatic stellate cells in liver fibrosis via IDH1/α-KG-mediated glycolysis.
Xu L, Yang TY, Zhou YW, Wu MF, Shen J, Cheng JL, Liu QX, Cao SY, Wang JQ, Zhang L
Acta pharmacologica Sinica 2022 Feb;43(2):316-329
Acta pharmacologica Sinica 2022 Feb;43(2):316-329
Multi-omics analyses reveal the mechanisms of Arsenic-induced male reproductive toxicity in mice.
Peng Z, Yang Q, Yeerken R, Chen J, Liu X, Li X
Journal of hazardous materials 2022 Feb 15;424(Pt C):127548
Journal of hazardous materials 2022 Feb 15;424(Pt C):127548
Acacetin alleviates myocardial ischaemia/reperfusion injury by inhibiting oxidative stress and apoptosis via the Nrf-2/HO-1 pathway.
Wu C, Chen RL, Wang Y, Wu WY, Li G
Pharmaceutical biology 2022 Dec;60(1):553-561
Pharmaceutical biology 2022 Dec;60(1):553-561
Heat shock protein Hspa13 regulates endoplasmic reticulum and cytosolic proteostasis through modulation of protein translocation.
Espinoza MF, Nguyen KK, Sycks MM, Lyu Z, Quanrud GM, Montoya MR, Genereux JC
The Journal of biological chemistry 2022 Dec;298(12):102597
The Journal of biological chemistry 2022 Dec;298(12):102597
A silk fibroin/chitosan/nanohydroxyapatite biomimetic bone scaffold combined with autologous concentrated growth factor promotes the proliferation and osteogenic differentiation of BMSCs and repair of critical bone defects.
Zhou Y, Liu X, She H, Wang R, Bai F, Xiang B
Regenerative therapy 2022 Dec;21:307-321
Regenerative therapy 2022 Dec;21:307-321
IL-22 inhibits bleomycin-induced pulmonary fibrosis in association with inhibition of IL-17A in mice.
Qu Z, Dou W, Zhang K, Duan L, Zhou D, Yin S
Arthritis research & therapy 2022 Dec 24;24(1):280
Arthritis research & therapy 2022 Dec 24;24(1):280
Investigation of the Therapeutic Effect of Total Alkaloids of Corydalis saxicola Bunting on CCl(4)-Induced Liver Fibrosis in Rats by LC/MS-Based Metabolomics Analysis and Network Pharmacology.
Wang Q, Luo Z, Li D, Qin J, Pan Z, Guo B, Deng L, Nong Y, Huang Z, He Y, Guo H, Zhu D, Liang Y, Su Z
Metabolites 2022 Dec 21;13(1)
Metabolites 2022 Dec 21;13(1)
Inhibition of BRD4 decreases fibrous scarring after ischemic stroke in rats by inhibiting the phosphorylation of Smad2/3.
Li X, Zhu H, Wen J, Huang J, Chen Y, Tian M, Ren J, Zhou L, Yang Q
Brain research 2022 Dec 15;1797:148126
Brain research 2022 Dec 15;1797:148126
Long noncoding RNA GAS5 inhibits LX-2 cells activation by suppressing NF-κB signalling through regulation of the miR-433-3p/TLR10 axis.
Su SB, Tao L, Liang XL, Chen W
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2022 Aug;54(8):1066-1075
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2022 Aug;54(8):1066-1075
CeO(2) nanoparticles induce pulmonary fibrosis via activating S1P pathway as revealed by metabolomics.
Cui L, Wang X, Zhao X, Sun B, Xia T, Hu S
Nano today 2022 Aug;45
Nano today 2022 Aug;45
18beta-glycyrrhetinic acid induces ROS-mediated apoptosis to ameliorate hepatic fibrosis by targeting PRDX1/2 in activated HSCs.
Zhang Q, Luo P, Zheng L, Chen J, Zhang J, Tang H, Liu D, He X, Shi Q, Gu L, Li J, Guo Q, Yang C, Wong YK, Xia F, Wang J
Journal of pharmaceutical analysis 2022 Aug;12(4):570-582
Journal of pharmaceutical analysis 2022 Aug;12(4):570-582
Circ_0047339 promotes the activation of fibroblasts and affects the development of urethral stricture by targeting the miR-4691-5p/TSP-1 axis.
Ding K, Li D, Zhang R, Zuo M
Scientific reports 2022 Aug 30;12(1):14746
Scientific reports 2022 Aug 30;12(1):14746
Evaluation of HZX-960, a novel DCN1-UBC12 interaction inhibitor, as a potential antifibrotic compound for liver fibrosis.
Zhou W, Dong G, Gao G, He Z, Xu J, Aziz S, Ma L, Zhao W
Biochemistry and cell biology = Biochimie et biologie cellulaire 2022 Aug 1;100(4):309-324
Biochemistry and cell biology = Biochimie et biologie cellulaire 2022 Aug 1;100(4):309-324
Strontium doped mesoporous silica nanoparticles accelerate osteogenesis and angiogenesis in distraction osteogenesis by activation of Wnt pathway.
Liu X, Sun Y, Shen J, Min HS, Xu J, Chai Y
Nanomedicine : nanotechnology, biology, and medicine 2022 Apr;41:102496
Nanomedicine : nanotechnology, biology, and medicine 2022 Apr;41:102496
Weighted correlation network analysis identifies FN1, COL1A1 and SERPINE1 associated with the progression and prognosis of gastric cancer.
Zhao Q, Xie J, Xie J, Zhao R, Song C, Wang H, Rong J, Yan L, Song Y, Wang F, Xie Y
Cancer biomarkers : section A of Disease markers 2021;31(1):59-75
Cancer biomarkers : section A of Disease markers 2021;31(1):59-75
Chinese Herbal Medicine Suyin Detoxification Granule Inhibits Pyroptosis and Epithelial-Mesenchymal Transition by Downregulating MAVS/NLRP3 to Alleviate Renal Injury.
Zhu Y, Huang G, Yang Y, Yong C, Yu X, Wang G, Yi L, Gao K, Tian F, Qian S, Zhou E, Zou Y
Journal of inflammation research 2021;14:6601-6618
Journal of inflammation research 2021;14:6601-6618
Costunolide Loaded in pH-Responsive Mesoporous Silica Nanoparticles for Increased Stability and an Enhanced Anti-Fibrotic Effect.
Niu X, Wang X, Niu B, Meng Y, He H, Wang Y, Li G
Pharmaceuticals (Basel, Switzerland) 2021 Sep 23;14(10)
Pharmaceuticals (Basel, Switzerland) 2021 Sep 23;14(10)
Macrophage exosomes transfer angiotensin II type 1 receptor to lung fibroblasts mediating bleomycin-induced pulmonary fibrosis.
Sun NN, Zhang Y, Huang WH, Zheng BJ, Jin SY, Li X, Meng Y
Chinese medical journal 2021 Sep 2;134(18):2175-2185
Chinese medical journal 2021 Sep 2;134(18):2175-2185
Ppic modulates CCl(4)-induced liver fibrosis and TGF-β-caused mouse hepatic stellate cell activation and regulated by miR-137-3p.
Yang X, Shu B, Zhou Y, Li Z, He C
Toxicology letters 2021 Oct 10;350:52-61
Toxicology letters 2021 Oct 10;350:52-61
Identification of collagen genes related to immune infiltration and epithelial-mesenchymal transition in glioma.
Yin W, Zhu H, Tan J, Xin Z, Zhou Q, Cao Y, Wu Z, Wang L, Zhao M, Jiang X, Ren C, Tang G
Cancer cell international 2021 May 25;21(1):276
Cancer cell international 2021 May 25;21(1):276
Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-βRI/Smad Signaling.
Luo X, Deng Q, Xue Y, Zhang T, Wu Z, Peng H, Xuan L, Pan G
Molecules (Basel, Switzerland) 2021 Mar 19;26(6)
Molecules (Basel, Switzerland) 2021 Mar 19;26(6)
Apigenin protects mice against 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced cholestasis.
Zheng S, Cao P, Yin Z, Wang X, Chen Y, Yu M, Xu B, Liao C, Duan Y, Zhang S, Han J, Yang X
Food & function 2021 Mar 15;12(5):2323-2334
Food & function 2021 Mar 15;12(5):2323-2334
Phgdh serves a protective role in Il‑1β induced chondrocyte inflammation and oxidative‑stress damage.
Huang H, Liu K, Ou H, Qian X, Wan J
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats.
Zhao Q, Hao C, Wei J, Huang R, Li C, Yao W
Ecotoxicology and environmental safety 2021 Jun 15;216:112181
Ecotoxicology and environmental safety 2021 Jun 15;216:112181
Nicotinamide mononucleotide attenuates isoproterenol-induced cardiac fibrosis by regulating oxidative stress and Smad3 acetylation.
Wu K, Li B, Lin Q, Xu W, Zuo W, Li J, Liu N, Tu T, Zhang B, Xiao Y, Liu Q
Life sciences 2021 Jun 1;274:119299
Life sciences 2021 Jun 1;274:119299
Quercetin prevents isoprenaline-induced myocardial fibrosis by promoting autophagy via regulating miR-223-3p/FOXO3.
Hu J, Wang X, Cui X, Kuang W, Li D, Wang J
Cell cycle (Georgetown, Tex.) 2021 Jul;20(13):1253-1269
Cell cycle (Georgetown, Tex.) 2021 Jul;20(13):1253-1269
Radiation‑induced dysfunction of energy metabolism in the heart results in the fibrosis of cardiac tissues.
Xu P, Yi Y, Luo Y, Liu Z, Xu Y, Cai J, Zeng Z, Liu A
Molecular medicine reports 2021 Dec;24(6)
Molecular medicine reports 2021 Dec;24(6)
DNMT1-Induced miR-152-3p Suppression Facilitates Cardiac Fibroblast Activation in Cardiac Fibrosis.
Xu SS, Ding JF, Shi P, Shi KH, Tao H
Cardiovascular toxicology 2021 Dec;21(12):984-999
Cardiovascular toxicology 2021 Dec;21(12):984-999
Kaposi's sarcoma-associated herpesvirus vFLIP promotes MEndT to generate hybrid M/E state for tumorigenesis.
Chen W, Ding Y, Liu D, Lu Z, Wang Y, Yuan Y
PLoS pathogens 2021 Dec;17(12):e1009600
PLoS pathogens 2021 Dec;17(12):e1009600
Dickkopf 3: a Novel Target Gene of miR-25-3p in Promoting Fibrosis-Related Gene Expression in Myocardial Fibrosis.
Zeng N, Wen YH, Pan R, Yang J, Yan YM, Zhao AZ, Zhu JN, Fang XH, Shan ZX
Journal of cardiovascular translational research 2021 Dec;14(6):1051-1062
Journal of cardiovascular translational research 2021 Dec;14(6):1051-1062
Diverging targets mediate the pathological roleof miR-199a-5p and miR-199a-3p by promoting cardiac hypertrophy and fibrosis.
Zeng N, Huang YQ, Yan YM, Hu ZQ, Zhang Z, Feng JX, Guo JS, Zhu JN, Fu YH, Wang XP, Zhang MZ, Duan JZ, Zheng XL, Xu JD, Shan ZX
Molecular therapy. Nucleic acids 2021 Dec 3;26:1035-1050
Molecular therapy. Nucleic acids 2021 Dec 3;26:1035-1050
Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.
Peng YF, Lin H, Liu DC, Zhu XY, Huang N, Wei YX, Li L
Cellular signalling 2021 Aug;84:110001
Cellular signalling 2021 Aug;84:110001
Expression of collagen type 1 alpha 1 indicates lymph node metastasis and poor outcomes in squamous cell carcinomas of the lung.
Dong S, Zhu P, Zhang S
PeerJ 2020;8:e10089
PeerJ 2020;8:e10089
Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.
Miao K, Pan T, Mou Y, Zhang L, Xiong W, Xu Y, Yu J, Wang Y
Therapeutic advances in chronic disease 2020;11:2040622320940185
Therapeutic advances in chronic disease 2020;11:2040622320940185
Low-magnitude vibration induces osteogenic differentiation of bone marrow mesenchymal stem cells via miR-378a-3p/Grb2 pathway to promote bone formation in a rat model of age-related bone loss.
Yu X, Zeng Y, Bao M, Wen J, Zhu G, Cao C, He X, Li L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):11754-11771
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):11754-11771
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl(4)-induced liver injury mouse model.
Ma X, Zhou Y, Qiao B, Jiang S, Shen Q, Han Y, Liu A, Chen X, Wei L, Zhou L, Zhao J
American journal of physiology. Endocrinology and metabolism 2020 May 1;318(5):E817-E829
American journal of physiology. Endocrinology and metabolism 2020 May 1;318(5):E817-E829
Sustained delivery of PlGF-2(123-144*)-fused BMP2-related peptide P28 from small intestinal submucosa/polylactic acid scaffold material for bone tissue regeneration.
Xiong Z, Cui W, Sun T, Teng Y, Qu Y, Yang L, Zhou J, Chen K, Yao S, Shao Z, Guo X
RSC advances 2020 Feb 13;10(12):7289-7300
RSC advances 2020 Feb 13;10(12):7289-7300
Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis.
Kobayashi Y, Tata A, Konkimalla A, Katsura H, Lee RF, Ou J, Banovich NE, Kropski JA, Tata PR
Nature cell biology 2020 Aug;22(8):934-946
Nature cell biology 2020 Aug;22(8):934-946
Novel role of the clustered miR-23b-3p and miR-27b-3p in enhanced expression of fibrosis-associated genes by targeting TGFBR3 in atrial fibroblasts.
Yang Z, Xiao Z, Guo H, Fang X, Liang J, Zhu J, Yang J, Li H, Pan R, Yuan S, Dong W, Zheng XL, Wu S, Shan Z
Journal of cellular and molecular medicine 2019 May;23(5):3246-3256
Journal of cellular and molecular medicine 2019 May;23(5):3246-3256
Autophagy Attenuates Angiotensin II-Induced Pulmonary Fibrosis by Inhibiting Redox Imbalance-Mediated NOD-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation.
Meng Y, Pan M, Zheng B, Chen Y, Li W, Yang Q, Zheng Z, Sun N, Zhang Y, Li X
Antioxidants & redox signaling 2019 Feb 1;30(4):520-541
Antioxidants & redox signaling 2019 Feb 1;30(4):520-541
Involvement of Smad3 pathway in atrial fibrosis induced by elevated hydrostatic pressure.
Wei W, Rao F, Liu F, Xue Y, Deng C, Wang Z, Zhu J, Yang H, Li X, Zhang M, Fu Y, Zhu W, Shan Z, Wu S
Journal of cellular physiology 2018 Jun;233(6):4981-4989
Journal of cellular physiology 2018 Jun;233(6):4981-4989
The effect of different hydroxyapatite microparticles on the osteogenic differentiation of MC3T3-E1 preosteoblasts.
Xu W, Xu C, Yi J, Dai H
Journal of materials chemistry. B 2018 Aug 28;6(32):5234-5242
Journal of materials chemistry. B 2018 Aug 28;6(32):5234-5242
LncRNA-ATB/microRNA-200a/β-catenin regulatory axis involved in the progression of HCV-related hepatic fibrosis.
Fu N, Zhao SX, Kong LB, Du JH, Ren WG, Han F, Zhang QS, Li WC, Cui P, Wang RQ, Zhang YG, Nan YM
Gene 2017 Jun 30;618:1-7
Gene 2017 Jun 30;618:1-7
Crucial Role of miR-433 in Regulating Cardiac Fibrosis.
Tao L, Bei Y, Chen P, Lei Z, Fu S, Zhang H, Xu J, Che L, Chen X, Sluijter JP, Das S, Cretoiu D, Xu B, Zhong J, Xiao J, Li X
Theranostics 2016;6(12):2068-2083
Theranostics 2016;6(12):2068-2083
Angiotensin(1-7) attenuated Angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H2O2-activated NLRP3 inflammasome/IL-1β/Smad circuit.
Zhang LL, Huang S, Ma XX, Zhang WY, Wang D, Jin SY, Zhang YP, Li Y, Li X
Free radical biology & medicine 2016 Aug;97:531-543
Free radical biology & medicine 2016 Aug;97:531-543
MicroRNA-130a and -130b enhance activation of hepatic stellate cells by suppressing PPARγ expression: A rat fibrosis model study.
Lu L, Wang J, Lu H, Zhang G, Liu Y, Wang J, Zhang Y, Shang H, Ji H, Chen X, Duan Y, Li Y
Biochemical and biophysical research communications 2015 Sep 25;465(3):387-93
Biochemical and biophysical research communications 2015 Sep 25;465(3):387-93
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