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LearnTissue expression
Cell line expression
MCF2L
gene productARHGEF14, DBS, KIAA0362, OST
This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
- Description
- MCF.2 cell line derived transforming sequence like
- Tissue specificity
- Tissue enhanced (brain)
- Predicted location
- Intracellular
- Protein family
- Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
- Chromosome
- 13:q34 (112894378 - 113099742)
- Ensembl ID
- ENSG00000126217 (ver. 103.38)
- Orthologs
- Mouse Mcf2l: ENSMUSG00000031442
- UniProt
- O15068
- neXtProt
- NX_O15068
Human splice variants
Mouse splice variants
* nTPM: Normalized TPM levels represent consensus gene expression calculated using two data sets. Read more
RNA data sourced from Human Protein Atlas.
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