27684-1-AP

antibody from Proteintech Group

Targeting: SF3B1 Hsh155, Prp10, PRPF10, SAP155, SF3b155

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

27684-1-AP

Provider

Proteintech Group

Product name

SF3B1 antibody

Antibody type

Polyclonal

Description

KD/KO validated SF3B1 antibody (Cat. #27684-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human and has been validated for the following applications: WB,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria.

Behera AK, Kim JJ, Kordale S, Pekovic F, Damodaran AP, Kumari B, Vidak S, Dickson E, Xiao MS, Duncan G, Andresson T, Misteli T, Valkov E, Gonatopoulos-Pournatzis T
Molecular cell 2026 Jan 8;86(1):41-59.e15

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CUL5 E3 ubiquitin ligase regulates the evasion of bladder cancer cells to CD8+ T cell-mediated killing by inhibiting autophagy.

Gao X, Yu Y, Sun J, Zhao H, You Y, Shi X, Wang K, Hong S, Xiong X, Huang C, Zhang H, Jiang G
PLoS biology 2026 Feb;24(2):e3003647

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A novel spliceosomopathy caused by de novo SF3B3 variants.

Musante L, Janos P, Pianigiani G, Cappelli S, Longo A, Alves C, Schwaibold EM, Wagner M, Costain G, Fridriksdottir R, Stefansson K, Sulem P, Lichtenbelt KD, van Binsbergen E, van Jaarsveld RH, Brusco A, Pavinato L, Biamino E, Spano A, Hildebrandt CC, Chan YM, Groopman E, Berkenstadt M, Koboldt D, Williamson R, Brunner HG, Vissers LE, Torring PM, Hao Q, Gelb BD, Goldmuntz E, Reed K, Bedoukian EC, Vecchio D, Salzano E, Piccione M, Zanus C, Mio C, Eichler EE, Wang T, Patterson WG, Butler KM, Piotrowski M, Mercier S, Cogné B, Wentzensen IM, Buratti E, Magistrato A, Faletra F
Genome medicine 2026 Feb 19;18(1)

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Pan-cancer oncogenic properties and therapeutic potential of SF3B4.

Shi Y, Pan Q, Chen W, Xie L, Tang S, Yang Z, Zhang M, Yin D, Lin L, Liao JY
Cancer gene therapy 2025 Jun;32(6):706-720

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SF3B1 thermostability as an assay for splicing inhibitor interactions.

Amorello AN, Chandrashekar Reddy G, Melillo B, Cravatt BF, Ghosh AK, Jurica MS
The Journal of biological chemistry 2025 Feb;301(2):108135

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RNA-coupled CRISPR Screens Reveal ZNF207 as a Regulator of LMNA Aberrant Splicing in Progeria.

Behera AK, Kim JJ, Kordale S, Damodaran AP, Kumari B, Vidak S, Dickson E, Xiao MS, Duncan G, Andresson T, Misteli T, Gonatopoulos-Pournatzis T
bioRxiv : the preprint server for biology 2025 Apr 26;

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Nuclear accumulation of YTHDF1 regulates mRNA splicing in the DNA damage response.

Hou J, Gao Y, Han B, Yan S, Wei S, Gao X
Science advances 2025 Apr 18;11(16):eado7660

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The PRMT6/STAT1/ACSL1 axis promotes ferroptosis in diabetic nephropathy.

Hong J, Li X, Hao Y, Xu H, Yu L, Meng Z, Zhang J, Zhu M
Cell death and differentiation 2024 Nov;31(11):1561-1575

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Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles.

Kamel W, Ruscica V, Embarc-Buh A, de Laurent ZR, Garcia-Moreno M, Demyanenko Y, Orton RJ, Noerenberg M, Madhusudhan M, Iselin L, Järvelin AI, Hannan M, Kitano E, Moore S, Merits A, Davis I, Mohammed S, Castello A
Molecular cell 2024 Dec 19;84(24):4896-4911.e7

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A transcription-independent mechanism determines rapid periodic fluctuations of BRCA1 expression.

Nie C, Zhou XA, Zhou J, Liu Z, Gu Y, Liu W, Zhan J, Li S, Xiong Y, Zhou M, Shen Q, Wang W, Yang E, Wang J
The EMBO journal 2023 Aug 1;42(15):e111951

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Splicing factor BUD31 promotes ovarian cancer progression through sustaining the expression of anti-apoptotic BCL2L12.

Wang Z, Wang S, Qin J, Zhang X, Lu G, Liu H, Guo H, Wu L, Shender VO, Shao C, Kong B, Liu Z
Nature communications 2022 Oct 21;13(1):6246

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Exploring the mechanistic link between SF3B1 mutation and ring sideroblast formation in myelodysplastic syndrome.

Ochi T, Fujiwara T, Ono K, Suzuki C, Nikaido M, Inoue D, Kato H, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Yokoyama H, Nakamura Y, Harigae H
Scientific reports 2022 Aug 26;12(1):14562

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Enterotoxigenic Bacteroidesfragilis Promotes Intestinal Inflammation and Malignancy by Inhibiting Exosome-Packaged miR-149-3p.

Cao Y, Wang Z, Yan Y, Ji L, He J, Xuan B, Shen C, Ma Y, Jiang S, Ma D, Tong T, Zhang X, Gao Z, Zhu X, Fang JY, Chen H, Hong J
Gastroenterology 2021 Nov;161(5):1552-1566.e12

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A splicing factor switch controls hematopoietic lineage specification of pluripotent stem cells.

Li Y, Wang D, Wang H, Huang X, Wen Y, Wang B, Xu C, Gao J, Liu J, Tong J, Wang M, Su P, Ren S, Ma F, Li HD, Bresnick EH, Zhou J, Shi L
EMBO reports 2021 Jan 7;22(1):e50535