MAB811

antibody from R&D Systems

Targeting: BMPR2 BMPR-II, BMPR3, BRK-3, PPH1, T-ALK

Western blot (Recommended by provider)

Antibody Data

Product number

MAB811

Provider

R&D Systems

Product name

Anti-Human BMPR-II Monoclonal Antibody (Clone 73805)

Antibody type

Monoclonal

Antigen

Mouse myeloma cell line NS0-derived recombinant human BMPR-II, Ala26-Ile151

Description

Protein A or G purified from hybridoma culture supernatant

Reactivity

Human

Host

Mouse

Antigen sequence

Q13873


Isotype

IgG

Vial size

500 µg

References

Submitted references

TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling.

Hurst LA, Dunmore BJ, Long L, Crosby A, Al-Lamki R, Deighton J, Southwood M, Yang X, Nikolic MZ, Herrera B, Inman GJ, Bradley JR, Rana AA, Upton PD, Morrell NW
Nature communications 2017 Jan 13;8:14079

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Casein kinase II contributes to the synergistic effects of BMP7 and BDNF on Smad 1/5/8 phosphorylation in septal neurons under hypoglycemic stress.

Chaverneff F, Barrett J
Journal of neurochemistry 2009 May;109(3):733-43

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A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7.

Sengle G, Ono RN, Lyons KM, Bächinger HP, Sakai LY
Journal of molecular biology 2008 Sep 12;381(4):1025-39

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Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism.

Dai J, Keller J, Zhang J, Lu Y, Yao Z, Keller ET
Cancer research 2005 Sep 15;65(18):8274-85