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BMPR2
Bone morphogenetic protein receptor type 2BMPR-II, BMPR3, BRK-3, PPH1, T-ALK
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, May 2020]
Top validated antibodies |
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| Invitrogen Antibodies |  MA5-15827 |
7 references | Monoclonal |
WB
ICC
IHC
FC
OA
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| antibodies-online | ABIN1105549 |
2 references | Monoclonal |
WB
EL
ICC
IHC
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| Abnova Corporation | PAB1907 |
2 references | Polyclonal |
WB
ICC
IHC
FC
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| GeneTex | GTX60415 |
1 references | Monoclonal |
WB
EL
ICC
IHC
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| Proteintech Group | 19087-1-AP |
Polyclonal |
WB
EL
IP
IHC
FC
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