Tissue expression
Cell line expression
Protein structure

CTLA4

Cytotoxic T-lymphocyte associated protein 4
CD, CD152, CELIAC3, CTLA-4, GSE, IDDM12 
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
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2137 antibodies from 50 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
R&D Systems
52 antibodies
Invitrogen Antibodies
124 antibodies
Novus Biologicals
218 antibodies
Abnova Corporation
13 antibodies
GeneTex
20 antibodies
antibodies-online
316 antibodies
OriGene
81 antibodies
Boster Biological Technology
2 antibodies
Biorbyt
118 antibodies
Antibodies.com
3 antibodies
ProSci
12 antibodies
NovoPro Bioscience Inc.
6 antibodies
NSJ Bioreagents
3 antibodies
Cusabio Biotech Co., Ltd
8 antibodies
Aviva Systems Biology
12 antibodies
FabGennix
3 antibodies
Affinity Biosciences
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
St John's Laboratory
13 antibodies
Abgent
3 antibodies
Acris Antibodies GmbH
18 antibodies
Bioworld Technology, Inc
1 antibody
Cambridge Research Biochemicals
4 antibodies
Cell Signaling Technology, Inc
4 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
Arigo
7 antibodies
BioLegend
55 antibodies
Creative Diagnostics
29 antibodies
Creative Biolabs
598 antibodies
MyBioSource
15 antibodies
Miltenyi Biotec
25 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
Abbexa
26 antibodies
RabMAbs
2 antibodies
Abbiotec
1 antibody
Abiocode, Inc.
1 antibody
EMD Millipore
1 antibody
MS Validated Antibodies GmbH
1 antibody
Proteintech Group
1 antibody
United States Biological
64 antibodies
GenWay
14 antibodies
eBioscience, An Affymetrix Company
8 antibodies
Leading Biology
2 antibodies
Sino Biological Inc.
8 antibodies
CPTAC
1 antibody
MedChemExpress LLC
1 antibody