Antibody data
- Antibody Data
- Antigen structure
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- Product number
- TAB-067 - Provider product page
- Provider
- Creative Biolabs
- Product name
- Anti-Human CTLA4 Recombinant Antibody (Ipilimumab)
- Antibody type
- Monoclonal
- Description
- Recombinant monoclonal antibody to CTLA4. Ipilimumab (known as MDX-010 and MDX-101), marketed as Yervoy, is a drug used for the treatment of melanoma, a type of skin cancer. It is a U.S. Food and Drug Administration (FDA) approved human monoclonal antibody, and works by activating the immune system by targeting CTLA-4.Cytotoxic T lymphocytes (CTLs) can recognize and destroy cancer cells. However, there is also an inhibitory mechanism that interrupts this destruction. Ipilimumab turns off this inhibitory mechanism and allows CTLs to continue to destroy cancer cells.
- Reactivity
- Human
- Host
- Human
- Storage
- 4¡ãC. For long term storage, aliquot and store at -20¡ãC. Repeated thawing and freezing must be avoided.
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