Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- FAB386P - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal CTLA-4 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human CTLA-4 in direct ELISAs and Western blots. In Western blots, approximately 25% cross-reactivity with recombinant mouse CTLA-4 is observed.
- Reactivity
- Human
- Host
- Goat
- Isotype
- IgG
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Submitted references CD26 expression and adenosine deaminase activity in regulatory T cells (Treg) and CD4(+) T effector cells in patients with head and neck squamous cell carcinoma.
Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells.
Mandapathil M, Szczepanski M, Harasymczuk M, Ren J, Cheng D, Jackson EK, Gorelik E, Johnson J, Lang S, Whiteside TL
Oncoimmunology 2012 Aug 1;1(5):659-669
Oncoimmunology 2012 Aug 1;1(5):659-669
Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells.
Mandapathil M, Hilldorfer B, Szczepanski MJ, Czystowska M, Szajnik M, Ren J, Lang S, Jackson EK, Gorelik E, Whiteside TL
The Journal of biological chemistry 2010 Mar 5;285(10):7176-86
The Journal of biological chemistry 2010 Mar 5;285(10):7176-86
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
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- Experimental details
- Detection of CTLA-4 in NS0 Mouse Cell Line Transfected with Human CTLA-4 and eGFP by Flow Cytometry. NS0 mouse myeloma cell line transfected with human CTLA-4 and eGFP was stained with (A) Goat Anti-Human CTLA-4 PE-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB386P) and (B) Normal Goat IgG Phycoerythrin Control (Catalog # IC108P). View our protocol for Staining Membrane-associated Proteins.