AF476

antibody from R&D Systems

Targeting: CTLA4 CD, CD152, CELIAC3, CTLA-4, GSE, IDDM12

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

AF476

Provider

R&D Systems

Product name

Mouse CTLA-4 Antibody

Antibody type

Polyclonal

Description

Antigen Affinity-purified. Detects mouse CTLA-4 in ELISAs and Western blots. In sandwich immunoassays, less than 1% cross-reactivity with recombinant human CTLA-4, recombinant mouse (rm) CD28, rmICOS, and rmPD-1 is observed.

Reactivity

Mouse

Host

Goat

Conjugate

Unconjugated

Antigen sequence

Q6GTR6


Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

The Circadian Clock Controls Immune Checkpoint Pathway in Sepsis.

Deng W, Zhu S, Zeng L, Liu J, Kang R, Yang M, Cao L, Wang H, Billiar TR, Jiang J, Xie M, Tang D
Cell reports 2018 Jul 10;24(2):366-378

---

Marked prolongation of cardiac allograft survival by dendritic cells genetically engineered with NF-kappa B oligodeoxyribonucleotide decoys and adenoviral vectors encoding CTLA4-Ig.

Bonham CA, Peng L, Liang X, Chen Z, Wang L, Ma L, Hackstein H, Robbins PD, Thomson AW, Fung JJ, Qian S, Lu L
Journal of immunology (Baltimore, Md. : 1950) 2002 Sep 15;169(6):3382-91

---

Marked prolongation of cardiac allograft survival by dendritic cells genetically engineered with NF-kappa B oligodeoxyribonucleotide decoys and adenoviral vectors encoding CTLA4-Ig.

Bonham CA, Peng L, Liang X, Chen Z, Wang L, Ma L, Hackstein H, Robbins PD, Thomson AW, Fung JJ, Qian S, Lu L
Journal of immunology (Baltimore, Md. : 1950) 2002 Sep 15;169(6):3382-91